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A statistical model of homopolymer DNA, coupling internal base pair states (unbroken or broken) and external thermal chain fluctuations, is exactly solved using transfer kernel techniques. The dependence on temperature and DNA length of the…

软凝聚态物质 · 物理学 2007-08-29 J. Palmeri , M. Manghi , N. Destainville

The role of thermal pressure fluctuations in the ejection of tightly packaged DNA from protein capsid shells is discussed in a model calculation. At equilibrium before ejection we assume the DNA is folded many times into a bundle of…

介观与纳米尺度物理 · 物理学 2010-09-20 Michael J. Harrison

DNA denaturation has long been a subject of intense study due to its relationship to DNA transcription and its fundamental importance as a nonlinear, structural transition. Many aspects of this phenomenon, however, remain poorly understood.…

介观与纳米尺度物理 · 物理学 2011-06-16 Kirill A. Velizhanin , Chih-Chun Chien , Yonatan Dubi , Michael Zwolak

The role of thermal pressure fluctuation excited within tightly packaged DNA prior to ejection from protein capsid shells is discussed in a model calculation. At equilibrium before ejection we assume the DNA is folded many times into a…

生物物理 · 物理学 2010-12-22 Michael J. Harrison

We use the "magnetic tweezers" technique to reveal the structural transitions that DNA undergoes in the force-torsion space. In particular, we focus on regions corresponding to negative supercoiling. These regions are characterized by the…

生物物理 · 物理学 2013-05-30 D. Salerno , A. Tempestini , I. Mai , D. Brogioli , R. Ziano , V. Cassina , F. Mantegazza

Energy decay plays a central role in a wide range of phenomena, such as optical emission, nuclear fission, and dissipation in quantum systems. Energy decay is usually described as a system leaking energy irreversibly into an environmental…

介观与纳米尺度物理 · 物理学 2016-12-14 J. Guettinger , A. Noury , P. Weber , A. M. Eriksson , C. Lagoin , J. Moser , C. Eichler , A. Wallraff , A. Isacsson , A. Bachtold

We predict a novel temperature-driven phase transition of DNA below the melting transition. The additional, intermediate phase exists for repetitive sequences, when the two strands have different lengths. In this phase, the excess bases of…

生物大分子 · 定量生物学 2007-05-23 Richard A. Neher , Ulrich Gerland

The exploration of the rich dynamics of electrons is a frontier in fundamental nano-physics. The dynamical behavior of electrons is dominated by random and chaotic thermal motion with ultrafast ($\approx$ ps) and nanoscale scatterings. This…

介观与纳米尺度物理 · 物理学 2021-08-11 Ruijie Qian , S. T. Chui , Zhenghua An , y Hongtao Xu , Zhifang Lin , Zian Ji , Wei Lu

Nanomechanical resonators promise diverse applications ranging from mass spectrometry to quantum information processing, requiring long phonon lifetimes and frequency stability. Although two-level system (TLS) defects govern dissipation at…

介观与纳米尺度物理 · 物理学 2025-01-15 M. P. Maksymowych , M. Yuksel , O. A. Hitchcock , N. R. Lee , F. M. Mayor , W. Jiang , M. L. Roukes , A. H. Safavi-Naeini

We study the size fluctuations of a local denaturation zone in a DNA molecule in the presence of proteins that selectively bind to single-stranded DNA, based on a (2+1)-dimensional master equation. By tuning the physical parameters we can…

生物大分子 · 定量生物学 2007-05-23 Tobias Ambjornsson , Ralf Metzler

We propose a nonlinear model derived from first principles, to describe bubble dynamics of DNA. Our model equations include a term derived from the dissipative effect of intermolecular vibrational modes. Such modes are excited by the…

软凝聚态物质 · 物理学 2007-05-23 Natalia Komarova , Avy Soffer

Fluctuation theorems are a generalization of thermodynamics on small scales and provide the tools to characterize the fluctuations of thermodynamic quantities in non-equilibrium nanoscale systems. They are particularly important for…

统计力学 · 物理学 2014-04-03 Jan Gieseler , Romain Quidant , Christoph Dellago , Lukas Novotny

The paper deals with the two-state (opening-closing of base pairs) model used to describe the fluctuation dynamics of a single bubble formation. We present an exact solution for the discrete and finite size version of the model that…

软凝聚态物质 · 物理学 2009-11-10 D. J. Bicout , E. Kats

We report on experiments addressing the non-linear interaction between a nano-mechanical mode and position fluctuations. The Duffing non-linearity transduces the Brownian motion of the mode, and of other non-linearly coupled ones, into…

介观与纳米尺度物理 · 物理学 2017-10-23 Olivier Maillet , Xin Zhou , Rasul Gazizulin , Ana Maldonado Cid , Martial Defoort , Olivier Bourgeois , Eddy Collin

The issue of the nucleation and slow closure mechanisms of non superhelical stress-induced denaturation bubbles in DNA is tackled using coarse-grained MetaDynamics and Brownian simulations. A minimal mesoscopic model is used where the…

软凝聚态物质 · 物理学 2015-04-13 François Sicard , Nicolas Destainville , Manoel Manghi

Statistical DNA models available in the literature are often effective models where the base-pair state only (unbroken or broken) is considered. Because of a decrease by a factor of 30 of the effective bending rigidity of a sequence of…

软凝聚态物质 · 物理学 2008-01-28 John Palmeri , Manoel Manghi , Nicolas Destainville

The thermodynamical stability of DNA minicircles is investigated by means of path integral techniques. Hydrogen bonds between base pairs on complementary strands can be broken by thermal fluctuations and temporary fluctuational openings…

软凝聚态物质 · 物理学 2015-03-30 Marco Zoli

Fluctuations of energy and heat are investigated during the relaxation following the instantaneous temperature quench of an extended system. Results are obtained analytically for the Gaussian model and for the large $N$ model quenched below…

统计力学 · 物理学 2015-06-22 M. Zannetti , F. Corberi , G. Gonnella , A. Piscitelli

The onset of intermediate states (denaturation bubbles) and their role during the melting transition of DNA are studied using the Peyrard-Bishop-Daxuois model by Monte Carlo simulations with no adjustable parameters. Comparison is made with…

统计力学 · 物理学 2009-11-10 S. Ares , N. K. Voulgarakis , K. O. Rasmussen , A. R. Bishop

In this paper we report direct measurement of large low frequency temperature fluctuations in double stranded (ds) DNA when it undergoes thermal denaturation transition. The fluctuation, which occurs only in the temperature range where the…

统计力学 · 物理学 2007-05-23 K. S. Nagapriya , A. K. Raychaudhuri , Dipankar Chatterji
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