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相关论文: A Survey of the State-of-the-Art Parallel Multiple…

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Analyzing the relation between a set of biological sequences can help to identify and understand the evolutionary history of these sequences and the functional relations among them. Multiple Sequence Alignment (MSA) is the main obstacle to…

定量方法 · 定量生物学 2017-08-07 Sara Shehab , Sameh Shohdy , Arabi E. Keshk

Multiple sequence alignment (MSA) has been one of the most important problems in bioinformatics for more decades and it is still heavily examined by many mathematicians and biologists. However, mostly because of the practical motivation of…

定量方法 · 定量生物学 2015-11-17 Kristóf Takács

Multiple sequence alignment (MSA) is a fundamental and ubiquitous technique in bioinformatics used to infer related residues among biological sequences. Thus alignment accuracy is crucial to a vast range of analyses, often in ways difficult…

定量方法 · 定量生物学 2015-01-09 Stefano Iantorno , Kevin Gori , Nick Goldman , Manuel Gil , Christophe Dessimoz

Multiple Sequence Alignment (MSA) is one of the most computationally intensive tasks in Computational Biology. Existing best known solutions for multiple sequence alignment take several hours (in some cases days) of computation time to…

分布式、并行与集群计算 · 计算机科学 2009-01-20 Fahad Saeed , Ashfaq Khokhar

Multiple Sequences Alignment (MSA) of biological sequences is a fundamental problem in computational biology due to its critical significance in wide ranging applications including haplotype reconstruction, sequence homology, phylogenetic…

分布式、并行与集群计算 · 计算机科学 2009-05-13 Fahad Saeed , Ashfaq Khokhar

Sequence alignment supports numerous tasks in bioinformatics, natural language processing, pattern recognition, social sciences, and others fields. While the alignment of two sequences may be performed swiftly in many applications, the…

数据结构与算法 · 计算机科学 2021-12-06 Eloi Araujo , Luiz Rozante , Diego P. Rubert , Fabio V. Martinez

The translation of comparative genomics into clinical decision support tools often depends on the quality of sequence alignments. However, currently used methods of multiple sequence alignments suffer from significant biases and problems…

基因组学 · 定量生物学 2023-11-30 Manal Helal , Vitali Sintchenko

Time Series Alignment is a critical task in signal processing with numerous real-world applications. In practice, signals often exhibit temporal shifts and scaling, making classification on raw data prone to errors. This paper introduces a…

机器学习 · 计算机科学 2025-02-27 Alireza Nourbakhsh , Hoda Mohammadzade

Sequence alignment is common nowadays as it is used in many fields to determine how closely two sequences are related and at times to see how little they differ. In computational biology / Bioinformatics, there are many algorithms developed…

信息论 · 计算机科学 2023-05-02 Bharath Reddy , Richard Fields

We propose an approach for multiple sequence alignment (MSA) derived from the dynamic time warping viewpoint and recent techniques of curve synchronization developed in the context of functional data analysis. Starting from pairwise…

应用统计 · 统计学 2017-01-09 Ana Arribas-Gil , Catherine Matias

Motivation: The multiple sequence alignment (MSA) problem has been extensively studied, with numerous approaches developed over recent years. With the rapid growth of sequence data, there is an increasing need for fast and accurate MSA…

计算工程、金融与科学 · 计算机科学 2026-01-23 Emily G. Light , Morgan Prior , Noah M. Daniels , Najib Ishaq

Data mining, particularly the analysis of multivariate time series data, plays a crucial role in extracting insights from complex systems and supporting informed decision-making across diverse domains. However, assessing the similarity of…

The alignment of biological sequences such as DNA, RNA, and proteins, is one of the basic tools that allow to detect evolutionary patterns, as well as functional/structural characterizations between homologous sequences in different…

定量方法 · 定量生物学 2023-05-01 Louise Budzynski , Andrea Pagnani

An overview of current multiple alignment systems to date are described.The useful algorithms, the procedures adopted and their limitations are presented.We also present the quality of the alignments obtained and in which cases(kind of…

数据结构与算法 · 计算机科学 2009-01-20 Fahad Saeed , Ashfaq Khokhar

Multiple sequence alignment (MSA) plays a key role in biological sequence analyses, especially in phylogenetic tree construction. Extreme increase in next-generation sequencing results in shortage of efficient ultra-large biological…

分布式、并行与集群计算 · 计算机科学 2017-04-05 Shixiang Wan , Quan Zou

Multiple sequence alignment is a basic procedure in molecular biology, and it is often treated as being essentially a solved computational problem. However, this is not so, and here I review the evidence for this claim, and outline the…

种群与进化 · 定量生物学 2018-08-24 David A. Morrison

The Multiple Sequence Alignment (MSA) is a computational abstraction that represents a partial summary either of indel history, or of structural similarity. Taking the former view (indel history), it is possible to use formal automata…

种群与进化 · 定量生物学 2015-06-04 Oscar Westesson , Gerton Lunter , Benedict Paten , Ian Holmes

Rapid development of modern sequencing platforms enabled an unprecedented growth of protein families databases. The abundance of sets composed of hundreds of thousands sequences is a great challenge for multiple sequence alignment…

基因组学 · 定量生物学 2017-03-03 Sebastin Deorowicz , Agnieszka Debudaj-Grabysz , Adam Gudys

In last decades optimization and control of complex systems that possessed various conflicted objectives simultaneously attracted an incremental interest of scientists. This is because of the vast applications of these systems in various…

神经与进化计算 · 计算机科学 2013-12-17 Ahmad Mozaffari , Alireza Fathi

Multimodal multi-objective problems (MMOPs) commonly arise in real-world problems where distant solutions in decision space correspond to very similar objective values. To obtain all solutions for MMOPs, many multimodal multi-objective…

神经与进化计算 · 计算机科学 2023-01-31 Wenhua Li , Tao Zhang , Rui Wang , Jing Liang
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