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A fundamental question in neuroscience is how the brain creates an internal model of the world to guide actions using sequences of ambiguous sensory information. This is naturally formulated as a reinforcement learning problem under partial…

机器学习 · 计算机科学 2020-11-02 Minhae Kwon , Saurabh Daptardar , Paul Schrater , Xaq Pitkow

The human brain copes with sensory uncertainty in accordance with Bayes' rule. However, it is unknown how the brain makes predictions in the presence of parameter uncertainty. Here, we tested whether and how humans take parameter…

神经元与认知 · 定量生物学 2020-07-01 Jannes Jegminat , Maya Jastrzebowska , Matt Pachai , Michael Herzog , Jean-Pascal Pfister

Real-world autonomous systems operate under uncertainty about both their pose and dynamics. Autonomous control systems must simultaneously perform estimation and control tasks to maintain robustness to changing dynamics or modeling errors.…

系统与控制 · 计算机科学 2018-08-03 Patrick Slade , Zachary N. Sunberg , Mykel J. Kochenderfer

Inverse optimization (IO) is used to estimate unknown parameters of an optimization model from observed decisions. In the data-driven context, the estimated parameters are inherently uncertain, yet quantifying this uncertainty has received…

最优化与控制 · 数学 2026-05-26 Timothy C. Y. Chan , Nathan Sandholtz , Nasrin Yousefi

Cerebral aneurysms and arteriovenous malformations are life-threatening hemodynamic pathologies of the brain. While surgical intervention is often essential to prevent fatal outcomes, it carries significant risks both during the procedure…

In safety-critical systems that interface with the real world, the role of uncertainty in decision-making is pivotal, particularly in the context of machine learning models. For the secure functioning of Cyber-Physical Systems (CPS), it is…

机器学习 · 计算机科学 2024-04-29 Neha Kumari , Sumit Kumar. Sneha Priya , Ayush Kumar , Akash Fogla

We present a Bayesian approach to estimate the parameters of mathematical models of cardiac electrophysiology with quantified uncertainty. Such models capture the dynamics of the electrical signal that coordinates the muscle cell…

数值分析 · 数学 2026-04-02 Maarten Volkaerts , Marie Cloet , Hans Dierckx , Piet Claus , Giovanni Samaey

We propose a general approach to the question of how biological rhythms spontaneously self-regulate, based on the concept of ``stochastic feedback''. We illustrate this approach by considering the neuroautonomic regulation of the heart…

统计力学 · 物理学 2009-10-30 Plamen Ch. Ivanov , Luis A. N. Amaral , Ary Goldberger , H. Eugene Stanley

Handling uncertainty is critical for ensuring reliable decision-making in intelligent systems. Modern neural networks are known to be poorly calibrated, resulting in predicted confidence scores that are difficult to use. This article…

机器学习 · 计算机科学 2026-05-18 Gabriele Sanguin , Arjun Pakrashi , Marco Viola , Francesco Rinaldi

Atrial Fibrillation (AF) is among one of the most common types of heart arrhythmia afflicting more than 3 million people in the U.S. alone. AF is estimated to be the cause of death of 1 in 4 individuals. Recent advancements in Artificial…

信号处理 · 电气工程与系统科学 2020-11-03 James Belen , Sajad Mousavi , Alireza Shamsoshoara , Fatemeh Afghah

Bayesian analysis is a framework for parameter estimation that applies even in uncertainty regimes where the commonly used local (frequentist) analysis based on the Cram\'er-Rao bound is not well defined. In particular, it applies when no…

量子物理 · 物理学 2021-03-17 Simon Morelli , Ayaka Usui , Elizabeth Agudelo , Nicolai Friis

A brain stroke occurs when blood flow to a part of the brain is disrupted, leading to cell death. Traditional stroke diagnosis methods, such as CT scans and MRIs, are costly and time-consuming. This study proposes a weighted voting ensemble…

机器学习 · 计算机科学 2025-04-22 Yao Zhiwan , Reza Zarrab , Jean Dubois

Electrocardiogram (ECG) is one of the non-invasive and low-risk methods to monitor the condition of the human heart. Any abnormal pattern(s) in the ECG signal is an indicative measure of malfunctioning of the heart, termed as arrhythmia.…

信号处理 · 电气工程与系统科学 2018-10-10 Sai Manoj Pudukotai Dinakarrao , Matthias Wess

Deep learning has shown promise in decoding brain signals, such as electroencephalogram (EEG), in the field of brain-computer interfaces (BCIs). However, the non-stationary characteristics of EEG signals pose challenges for training neural…

机器学习 · 计算机科学 2023-11-16 Byeong-Hoo Lee , Byoung-Hee Kwon , Seong-Whan Lee

Gaussian processes that can be decomposed into a smooth mean function and a stationary autocorrelated noise process are considered and a fully automatic nonparametric method to simultaneous estimation of mean and auto-covariance functions…

统计方法学 · 统计学 2021-08-19 Tatyana Krivobokova , Paulo Serra , Francisco Rosales , Karolina Klockmann

The cognitive mechanisms underlying subjects' self-regulation in Brain-Computer Interface (BCI) and neurofeedback (NF) training remain poorly understood. Yet, a mechanistic computational model of each individual learning trajectory is…

人机交互 · 计算机科学 2024-10-10 Côme Annicchiarico , Fabien Lotte , Jérémie Mattout

The idea that the brain is a probabilistic (Bayesian) inference machine, continuously trying to figure out the hidden causes of its inputs, has become very influential in cognitive (neuro)science over recent decades. Here I present a…

神经元与认知 · 定量生物学 2024-02-15 Eelke Spaak

Women are underdiagnosed and undertreated for cardiovascular disease. Automatic quantification of breast arterial calcification on screening mammography can identify women at risk for cardiovascular disease and enable earlier treatment and…

Extensive research has been performed on continuous, non-invasive, cuffless blood pressure (BP) measurement using artificial intelligence algorithms. This approach involves extracting certain features from physiological signals like ECG,…

医学物理 · 物理学 2023-04-03 Ali Farki , Reza Baradaran Kazemzadeh , Elham Akhondzadeh Noughabi

Recent research is revealing how cognitive processes are supported by a complex interplay between the brain and the rest of the body, which can be investigated by the analysis of physiological features such as breathing rhythms, heart rate,…

定量方法 · 定量生物学 2023-03-10 Fernando E. Rosas , Diego Candia-Rivera , Andrea I Luppi , Yike Guo , Pedro A. M. Mediano