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Recent advances in engineering technologies have enabled the collection of a large number of longitudinal features. This wealth of information presents unique opportunities for researchers to investigate the complex nature of diseases and…

统计方法学 · 统计学 2023-11-27 Zihang Lu , Noirrit Kiran Chandra

Joint latent class modelling has been developed considerably in the past two decades. In some instances, the models are linked by the latent class k (i.e. the number of subgroups), in others they are joined by shared random effects or a…

统计方法学 · 统计学 2023-03-02 Ruoyu Miao , Christiana Charalambous

In this paper, we propose a semiparametric, tree based joint latent class modeling approach (JLCT) to model the joint behavior of longitudinal and time-to-event data. Existing joint latent class modeling approaches are parametric and can…

统计方法学 · 统计学 2020-10-09 Ningshan Zhang , Jeffrey S. Simonoff

Joint models of longitudinal and survival data have become an important tool for modeling associations between longitudinal biomarkers and event processes. The association between marker and log-hazard is assumed to be linear in existing…

统计方法学 · 统计学 2017-10-24 Meike Köhler , Nikolaus Umlauf , Sonja Greven

Objectives To investigate the use of a Bayesian joint modelling approach to predict overall survival (OS) from immature clinical trial data using an intermediate biomarker. To compare the results with a typical parametric approach of…

Finite mixture models have become a popular tool for clustering. Amongst other uses, they have been applied for clustering longitudinal data and clustering high-dimensional data. In the latter case, a latent Gaussian mixture model is…

统计方法学 · 统计学 2018-04-17 Vanessa S. E. Bierling , Paul D. McNicholas

In applications such as biomedical studies, epidemiology, and social sciences, recurrent events often co-occur with longitudinal measurements and a terminal event, such as death. Therefore, jointly modeling longitudinal measurements,…

机器学习 · 统计学 2024-04-08 Zhiyue Zhang , Yao Zhao , Yanxun Xu

A novel extrapolation method is proposed for longitudinal forecasting. A hierarchical Gaussian process model is used to combine nonlinear population change and individual memory of the past to make prediction. The prediction error is…

统计方法学 · 统计学 2014-08-25 Leo L. Duan , John P. Clancy , Rhonda D. Szczesniak

Temporal inhomogeneities observed in various natural and social phenomena have often been characterized in terms of scaling behaviors in the autocorrelation function with a decaying exponent $\gamma$, the interevent time distribution with a…

物理与社会 · 物理学 2018-08-20 Byoung-Hwa Lee , Woo-Sung Jung , Hang-Hyun Jo

Fitting spatio-temporal models for areal data is crucial in many fields such as cancer epidemiology. However, when data sets are very large, many issues arise. The main objective of this paper is to propose a general procedure to analyze…

统计方法学 · 统计学 2023-02-06 E. Orozco-Acosta , A. Adin , M. D. Ugarte

Joint models (JMs) for longitudinal and time-to-event data are an important class of biostatistical models in health and medical research. When the study population consists of heterogeneous subgroups, the standard JM may be inadequate and…

统计方法学 · 统计学 2024-10-31 Sida Chen , Danilo Alvares , Marco Palma , Jessica K. Barrett

In this review paper, some applications of the mixed effect modeling in medial image processing and longitudinal analysis is studied. For this purpose, a general structure is extracted from some of the researches in the literature. This…

医学物理 · 物理学 2018-03-13 Fatemeh Nasiri , Oscar Acosta-Tamayo

We consider a joint survival and mixed-effects model to explain the survival time from longitudinal data and high-dimensional covariates in a population. The longitudinal data is modeled using a non linear mixed-effects model to account for…

统计理论 · 数学 2025-08-06 Antoine Caillebotte , Estelle Kuhn , Sarah Lemler

Survival of living tumor cells underlies many influences such as nutrient saturation, oxygen level, drug concentrations or mechanical forces. Data-supported mathematical modeling can be a powerful tool to get a better understanding of cell…

Longitudinal biomarker data and health outcomes are routinely collected in many studies to assess how biomarker trajectories predict health outcomes. Existing methods primarily focus on mean biomarker profiles, treating variability as a…

This paper takes a quick look at Bayesian joint models (BJM) for longitudinal and survival data. A general formulation for BJM is examined in terms of the sampling distribution of the longitudinal and survival processes, the conditional…

统计方法学 · 统计学 2020-05-27 Carmen Armero

The task of clustering a set of objects based on multiple sources of data arises in several modern applications. We propose an integrative statistical model that permits a separate clustering of the objects for each data source. These…

机器学习 · 统计学 2015-12-01 Eric F. Lock , David B. Dunson

In the U.S., lung cancer is the second major cause of death. Early detection of suspicious lung nodules is crucial for patient treatment planning, management, and improving outcomes. Many approaches for lung nodule segmentation and…

图像与视频处理 · 电气工程与系统科学 2025-04-10 Tejas Sudharshan Mathai , Benjamin Hou , Ronald M. Summers

Dyadic data are common in the social and behavioral sciences, in which members of dyads are correlated due to the interdependence structure within dyads. The analysis of longitudinal dyadic data becomes complex when nonignorable dropouts…

应用统计 · 统计学 2012-06-29 Guangyu Zhang , Ying Yuan

Longitudinal and survival sub-models are two building blocks for joint modelling of longitudinal and time to event data. Extensive research indicates separate analysis of these two processes could result in biased outputs due to their…

统计方法学 · 统计学 2022-09-22 Zili Zhang , Christiana Charalambous , Peter Foster