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Neurons and networks in the cerebral cortex must operate reliably despite multiple sources of noise. To evaluate the impact of both input and output noise, we determine the robustness of single-neuron stimulus selective responses, as well…

神经元与认知 · 定量生物学 2018-01-24 Ran Rubin , L. F. Abbott , Haim Sompolinsky

Understanding how the complex connectivity structure of the brain shapes its information-processing capabilities is a long-standing question. By focusing on a paradigmatic architecture, we study how the neural activity of excitatory and…

统计力学 · 物理学 2024-10-18 Giacomo Barzon , Daniel Maria Busiello , Giorgio Nicoletti

Dynamical balance of excitation and inhibition is usually invoked to explain the irregular low firing activity observed in the cortex. We propose a robust nonlinear balancing mechanism for a random network of spiking neurons, which works…

无序系统与神经网络 · 物理学 2025-05-29 Antonio Politi , Alessandro Torcini

Inhibitory neurons play a crucial role in maintaining persistent neuronal activity. Although connected extensively through electrical synapses (gap-junctions), these neurons also exhibit interactions through chemical synapses in certain…

神经元与认知 · 定量生物学 2021-04-08 R. Janaki , A. S. Vytheeswaran

Maximum Entropy models can be inferred from large data-sets to uncover how collective dynamics emerge from local interactions. Here, such models are employed to investigate neurons recorded by multielectrode arrays in the human and monkey…

神经元与认知 · 定量生物学 2018-07-11 Trang-Anh Nghiem , Bartosz Telenczuk , Olivier Marre , Alain Destexhe , Ulisse Ferrari

Balance of excitation and inhibition is a fundamental feature of in vivo network activity and is important for its computations. However, its presence in the neocortex of higher mammals is not well established. We investigated the dynamics…

Understanding how network function constrains neural connectivity is a central challenge in neuroscience. An influential approach is to train neural networks with gradient descent on cognitive tasks and characterize the resulting…

神经元与认知 · 定量生物学 2026-05-26 Ludwig Hruza , Srdjan Ostojic

Complexity in the temporal organization of neural systems may be a reflection of the diversity of its neural constituents. These constituents, excitatory and inhibitory neurons, comprise an invariant ratio in vivo and form the substrate for…

神经元与认知 · 定量生物学 2015-05-18 Xin Chen , Rhonda Dzakpasu

In this work, we study the dynamic range of a neuronal network of excitable neurons with excitatory and inhibitory synapses. We obtain an analytical expression for the critical point as a function of the excitatory and inhibitory synaptic…

神经元与认知 · 定量生物学 2020-08-24 F S Borges , P R Protachevicz , V Santos , M S Santos , E C Gabrick , K C Iarosz , E L Lameu , M S Baptista , I L Caldas , A M Batista

Many experiments have evidenced that electrical and chemical synapses -- hybrid synapses -- coexist in most organisms and brain structures. The role of electrical and chemical synapse connection in diversity of neural activity generation…

神经元与认知 · 定量生物学 2021-08-11 Kesheng Xu , Jean Paul Maidana , Patricio Orio

Performing more tasks in parallel is a typical feature of complex brains. These are characterized by the coexistence of excitatory and inhibitory synapses, whose percentage in mammals is measured to have a typical value of 20-30\%. Here we…

神经元与认知 · 定量生物学 2015-08-25 Vittorio Capano , Hans J. Herrmann , Lucilla de Arcangelis

Spiking neural networks drawing inspiration from biological constraints of the brain promise an energy-efficient paradigm for artificial intelligence. However, challenges exist in identifying guiding principles to train these networks in a…

神经与进化计算 · 计算机科学 2024-04-25 Joseph A. Kilgore , Jeffrey D. Kopsick , Giorgio A. Ascoli , Gina C. Adam

How the information microscopically processed by individual neurons is integrated and used in organizing the behavior of an animal is a central question in neuroscience. The coherence of neuronal dynamics over different scales has been…

无序系统与神经网络 · 物理学 2020-03-11 Takashi Hayakawa , Tomoki Fukai

Large networks of sparsely coupled, excitatory and inhibitory cells occur throughout the brain. A striking feature of these networks is that they are chaotic. How does this chaos manifest in the neural code? Specifically, how variable are…

神经元与认知 · 定量生物学 2014-02-25 Guillaume Lajoie , Jean-Philippe Thivierge , Eric Shea-Brown

Many biological neuronal networks exhibit highly variable spiking activity. Balanced networks offer a parsimonious model of this variability. In balanced networks, strong excitatory synaptic inputs are canceled by strong inhibitory inputs…

神经元与认知 · 定量生物学 2016-05-04 Ryan Pyle , Robert Rosenbaum

The construction of biologically plausible models of neural circuits is crucial for understanding the computational properties of the nervous system. Constructing functional networks composed of separate excitatory and inhibitory neurons…

无序系统与神经网络 · 物理学 2020-07-01 Alessandro Ingrosso , L. F. Abbott

Using results from neurobiology on perceptual decision making and value-based decision making, the problem of decision making between lotteries is reformulated in an abstract space where uncertain prospects are mapped to corresponding…

神经元与认知 · 定量生物学 2020-01-03 Adnan Rebei

The mammalian brain could contain dense and sparse network connectivity structures, including both excitatory and inhibitory neurons, but is without any clearly defined output layer. The neurons have time constants, which mean that the…

神经元与认知 · 定量生物学 2021-06-04 Udaya B. Rongala , Henrik Jörntell

Networks of model neurons with balanced recurrent excitation and inhibition produce irregular and asynchronous spiking activity. We extend the analysis of balanced networks to include the known dependence of connection probability on the…

神经元与认知 · 定量生物学 2014-06-02 Robert Rosenbaum , Brent Doiron

The "edge of chaos" phase transition in artificial neural networks is of renewed interest in light of recent evidence for criticality in brain dynamics. Statistical mechanics traditionally studied this transition with connectivity $k$ as…

无序系统与神经网络 · 物理学 2019-07-17 Lorenz Baumgarten , Stefan Bornholdt
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