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Information is a key concept in evolutionary biology. Information is stored in biological organism's genomes, and used to generate the organism as well as to maintain and control it. Information is also "that which evolves". When a…

种群与进化 · 定量生物学 2012-07-25 Christoph Adami

For biological experiments aiming at calibrating models with unknown parameters, a good experimental design is crucial, especially for those subject to various constraints, such as financial limitations, time consumption and physical…

应用统计 · 统计学 2014-07-22 Xiao Lin , Gabriel Terejanu

Biological populations are subject to fluctuating environmental conditions. Different adaptive strategies can allow them to cope with these fluctuations: specialization to one particular environmental condition, adoption of a generalist…

种群与进化 · 定量生物学 2017-09-27 Andreas Mayer , Thierry Mora , Olivier Rivoire , Aleksandra M. Walczak

Biochemical signaling cascades transmit intracellular information while dissipating energy under nonequilibrium conditions. We model a cascade as a code string and apply information-entropy ideas to quantify an optimal transmission rate. A…

分子网络 · 定量生物学 2026-01-21 Tatsuaki Tsuruyama

Living systems are often described utilizing informational analogies. An important open question is whether information is merely a useful conceptual metaphor, or intrinsic to the operation of biological systems. To address this question,…

分子网络 · 定量生物学 2015-08-19 Hyunju Kim , Paul Davies , Sara Imari Walker

Molecular recognition, which is essential in processing information in biological systems, takes place in a crowded noisy biochemical environment and requires the recognition of a specific target within a background of various similar…

生物大分子 · 定量生物学 2010-07-27 Yonatan Savir , Tsvi Tlusty

Deviations from rational decision-making due to limited computational resources have been studied in the field of bounded rationality, originally proposed by Herbert Simon. There have been a number of different approaches to model bounded…

人工智能 · 计算机科学 2015-11-06 Jordi Grau-Moya , Daniel A. Braun

An important feature of many complex systems, both natural and artificial, is the structure and organization of their interaction networks with interesting properties. Here we present a theory of self-organization by evolutionary adaptation…

适应与自组织系统 · 物理学 2007-05-23 Venkat Venkatasubramanian , Santhoji Katare , Priyan R. Patkar , Fangping Mu

We study an interacting particle system whose dynamics depends on an interacting random environment. As the number of particles grows large, the transition rate of the particles slows down (perhaps because they share a common resource of…

概率论 · 数学 2009-02-16 Charles Bordenave , David McDonald , Alexandre Proutiere

In adaptive networks fragmentation transitions have been observed in which the network breaks into disconnected components. We present an analytical approach for calculating the transition point in general adaptive network models. Using the…

适应与自组织系统 · 物理学 2012-06-08 Gesa A. Böhme , Thilo Gross

The Independent Cascade Model (ICM) is a widely studied model that aims to capture the dynamics of the information diffusion in social networks and in general complex networks. In this model, we can distinguish between active nodes which…

数据结构与算法 · 计算机科学 2017-06-21 Gianlorenzo D'Angelo , Lorenzo Severini , Yllka Velaj

The energy cost of computation has emerged as a central challenge at the intersection of physics and computer science. Recent advances in statistical physics -- particularly in stochastic thermodynamics -- enable precise characterizations…

统计力学 · 物理学 2025-10-07 Jinghao Lyu , Kyle J. Ray , James P. Crutchfield

Sensory observations about the world are invariably ambiguous. Inference about the world's latent variables is thus an important computation for the brain. However, computational constraints limit the performance of these computations.…

神经元与认知 · 定量生物学 2022-10-13 Lokesh Boominathan , Xaq Pitkow

Cells must continuously sense and respond to time-varying environmental stimuli. These signals are transmitted and processed by biochemical signalling networks. However, the biochemical reactions making up these networks are intrinsically…

分子网络 · 定量生物学 2015-05-18 Filipe Tostevin , Pieter Rein ten Wolde

In an adaptive population which models financial markets and distributed control, we consider how the dynamics depends on the diversity of the agents' initial preferences of strategies. When the diversity decreases, more agents tend to…

物理与社会 · 物理学 2008-12-02 H. M. Yang , Y. S. Ting , K. Y. Michael Wong

Adaptation to environmental change is a common property of biological systems. Cells initially respond to external changes in the environment, but after some time, they regain their original state. By considering an element consisting of…

生物物理 · 物理学 2015-05-13 Masayo Inoue , Kunihiko Kaneko

In the ecological approach to perception and action, information that specifies affordances is available in the energy arrays surrounding organisms, and this information is detected by organisms in order to perceptually guide their actions.…

神经元与认知 · 定量生物学 2023-11-20 Vicente Raja , Matthieu M. de Wit

Real-world complex systems such as ecological communities and neuron networks are essential parts of our everyday lives. These systems are composed of units which interact through intricate networks. The ability to predict sudden changes in…

适应与自组织系统 · 物理学 2019-07-05 Deniz Eroglu , Matteo Tanzi , Sebastian van Strien , Tiago Pereira

Unlike many physical nonequilibrium systems, in biological systems, the coupling to external energy sources is not a fixed parameter but adaptively controlled by the system itself. We do not have theoretical frameworks that allow for such…

种群与进化 · 定量生物学 2025-06-30 Ankit Dhanuka , Avi I. Flamholz , Arvind Murugan , Akshit Goyal