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One major challenge in neuroscience is the identification of interrelations between signals reflecting neural activity and how information processing occurs in the neural circuits. At the cellular and molecular level, mechanisms of signal…

应用统计 · 统计学 2019-09-27 Giacomo Aletti , Davide Lonardoni , Giovanni Naldi , Thierry Nieus

The firing dynamics of biological neurons in mathematical models is often determined by the model's parameters, representing the neurons' underlying properties. The parameter estimation problem seeks to recover those parameters of a single…

神经元与认知 · 定量生物学 2022-10-05 Long Le , Yao Li

Collective rhythmic dynamics from neurons is vital for cognitive functions such as memory formation but how neurons self-organize to produce such activity is not well understood. Attractor-based models have been successfully implemented as…

神经元与认知 · 定量生物学 2013-03-22 Mark Niedringhaus , Xin Chen , Katherine Conant , Rhonda Dzakpasu

The mammalian brain could contain dense and sparse network connectivity structures, including both excitatory and inhibitory neurons, but is without any clearly defined output layer. The neurons have time constants, which mean that the…

神经元与认知 · 定量生物学 2021-06-04 Udaya B. Rongala , Henrik Jörntell

In this paper we address the question of statistical model selection for a class of stochastic models of biological neural nets. Models in this class are systems of interacting chains with memory of variable length. Each chain describes the…

统计理论 · 数学 2018-12-19 A. Duarte , A. Galves , E. Löcherbach , G. Ost

Third-generation neural networks, or Spiking Neural Networks (SNNs), aim at harnessing the energy efficiency of spike-domain processing by building on computing elements that operate on, and exchange, spikes. In this paper, the problem of…

机器学习 · 统计学 2018-02-23 Alireza Bagheri , Osvaldo Simeone , Bipin Rajendran

We present a simple Markov model of spiking neural dynamics that can be analytically solved to characterize the stochastic dynamics of a finite-size spiking neural network. We give closed-form estimates for the equilibrium distribution,…

神经元与认知 · 定量生物学 2007-05-23 H. Soula , C. C. Chow

Neuronal dynamics are fundamentally constrained by the underlying structural network architecture, yet much of the details of this synaptic connectivity are still unknown even in neuronal cultures in vitro. Here we extend a previous…

神经元与认知 · 定量生物学 2017-02-08 Javier G. Orlandi , Olav Stetter , Jordi Soriano , Theo Geisel , Demian Battaglia

Legged locomotion is a challenging task in the field of robotics but a rather simple one in nature. This motivates the use of biological methodologies as solutions to this problem. Central pattern generators are neural networks that are…

神经与进化计算 · 计算机科学 2020-03-18 Elie Aljalbout , Florian Walter , Florian Röhrbein , Alois Knoll

Neuronal dynamics is intrinsically unstable, producing activity fluctuations that are essentially scale-free. Here we show that while these scale-free fluctuations are independent of temporal input statistics, they can be entrained by input…

神经元与认知 · 定量生物学 2013-05-02 Asaf Gal , Shimon Marom

While spike timing has been shown to carry detailed stimulus information at the sensory periphery, its possible role in network computation is less clear. Most models of computation by neural networks are based on population firing rates.…

神经元与认知 · 定量生物学 2015-07-17 Michael A. Schwemmer , Adrienne L. Fairhall , Sophie Denéve , Eric T. Shea-Brown

Emerging technologies are revealing the spiking activity in ever larger neural ensembles. Frequently, this spiking is far from independent, with correlations in the spike times of different cells. Understanding how such correlations impact…

神经元与认知 · 定量生物学 2013-05-20 James Trousdale , Yu Hu , Eric Shea-Brown , Krešimir Josić

Understanding how the dynamics of neural networks is shaped by the computations they perform is a fundamental question in neuroscience. Recently, the framework of efficient coding proposed a theory of how spiking neural networks can compute…

神经元与认知 · 定量生物学 2022-10-25 Veronika Koren , Stefano Panzeri

Identification of patterns from discrete data time-series for statistical inference, threat detection, social opinion dynamics, brain activity prediction has received recent momentum. In addition to the huge data size, the associated…

机器学习 · 计算机科学 2019-02-22 Ruochen Yang , Gaurav Gupta , Paul Bogdan

Now that spike trains from many neurons can be recorded simultaneously, there is a need for methods to decode these data to learn about the networks that these neurons are part of. One approach to this problem is to adjust the parameters of…

定量方法 · 定量生物学 2011-06-10 John Hertz , Yasser Roudi , Joanna Tyrcha

Basic principles of statistical inference are commonly violated in network data analysis. Under the current approach, it is often impossible to identify a model that accommodates known empirical behaviors, possesses crucial inferential…

统计理论 · 数学 2017-01-02 Harry Crane , Walter Dempsey

One of the focus areas of modern scientific research is to reveal mysteries related to genes and their interactions. The dynamic interactions between genes can be encoded into a gene regulatory network (GRN), which can be used to gain…

最优化与控制 · 数学 2020-07-16 Atte Aalto , Lauri Viitasaari , Pauliina Ilmonen , Laurent Mombaerts , Jorge Goncalves

A semi-parametric, non-linear regression model in the presence of latent variables is applied towards learning network graph structure. These latent variables can correspond to unmodeled phenomena or unmeasured agents in a complex system of…

机器学习 · 统计学 2018-07-03 Jonathan Mei , José M. F. Moura

A pervasive challenge in neuroscience is testing whether neuronal connectivity changes over time due to specific causes, such as stimuli, events, or clinical interventions. Recent hardware innovations and falling data storage costs enable…

神经元与认知 · 定量生物学 2024-01-05 Johan Medrano , Karl J. Friston , Peter Zeidman

The principles of neural encoding and computations are inherently collective and usually involve large populations of interacting neurons with highly correlated activities. While theories of neural function have long recognized the…

神经元与认知 · 定量生物学 2019-05-14 Christophe Gardella , Olivier Marre , Thierry Mora