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Grid cells in the entorhinal cortex of mammalian brains exhibit striking hexagon grid firing patterns in their response maps as the animal (e.g., a rat) navigates in a 2D open environment. In this paper, we study the emergence of the…

神经元与认知 · 定量生物学 2024-02-21 Dehong Xu , Ruiqi Gao , Wen-Hao Zhang , Xue-Xin Wei , Ying Nian Wu

Grid cells in the medial entorhinal cortex and place cells in the hippocampus together support spatial navigation. The two regions are reciprocally connected, and there is a chicken-and-egg problem for how both arise and reinforce each…

神经元与认知 · 定量生物学 2026-05-21 Zhaoze Wang , Genela Morris , Dori Derdikman , Pratik Chaudhari , Vijay Balasubramanian

Grid cells in the medial entorhinal cortex (MEC) of the mammalian brain exhibit a strikingly regular hexagonal firing field over space. These cells are learned after birth and are thought to support spatial navigation but also more abstract…

神经元与认知 · 定量生物学 2024-10-07 Mufeng Tang , Helen Barron , Rafal Bogacz

Grid cells in the entorhinal cortex, together with head direction, place, speed and border cells, are major contributors to the organization of spatial representations in the brain. In this work we introduce a novel theoretical and…

神经元与认知 · 定量生物学 2019-07-25 Fabio Anselmi , Micah M. Murray , Benedetta Franceschiello

Grid cells are believed to play an important role in both spatial and non-spatial cognition tasks. A recent study observed the emergence of grid cells in an LSTM for path integration. The connection between biological and artificial neural…

神经元与认知 · 定量生物学 2020-09-10 Li Songlin , Deng Yangdong , Wang Zhihua

How does the mind organize thoughts? The hippocampal-entorhinal complex is thought to support domain-general representation and processing of structural knowledge of arbitrary state, feature and concept spaces. In particular, it enables the…

人工智能 · 计算机科学 2022-02-24 Paul Stoewer , Christian Schlieker , Achim Schilling , Claus Metzner , Andreas Maier , Patrick Krauss

The grid firing patterns are thought to provide an efficient intrinsic metric capable of supporting universal spatial metric for mammalian spatial navigation in all environments. However, whether spatial representations of grid cells in the…

神经元与认知 · 定量生物学 2019-10-14 Taiping Zeng , XiaoLi Li , Bailu Si

The spatial responses of many of the cells recorded in all layers of rodent medial entorhinal cortex (mEC) show a triangular grid pattern, and once established might be based in part on path-integration mechanisms. Grid axes are tightly…

神经元与认知 · 定量生物学 2012-03-20 Bailu Si , Emilio Kropff , Alessandro Treves

Can neural networks learn goal-directed behaviour using similar strategies to the brain, by combining the relationships between the current state of the organism and the consequences of future actions? Recent work has shown that recurrent…

神经元与认知 · 定量生物学 2021-01-21 Justin Jude , Matthias H. Hennig

The grid cells (GCs) of the medial entorhinal cortex (MEC) and place cells (PCs) of the hippocampus are key elements of the brain network for the metric representation of space. Currently, any of the existing theoretical models can explain…

神经元与认知 · 定量生物学 2015-07-01 Andrey Stepanyuk

The activity of the grid cell population in the medial entorhinal cortex (MEC) of the mammalian brain forms a vector representation of the self-position of the animal. Recurrent neural networks have been proposed to explain the properties…

神经元与认知 · 定量生物学 2022-11-08 Dehong Xu , Ruiqi Gao , Wen-Hao Zhang , Xue-Xin Wei , Ying Nian Wu

Artificial neural networks have realized incredible successes at image recognition, but the underlying mechanism of visual space representation remains a huge mystery. Grid cells (2014 Nobel Prize) in the entorhinal cortex support a…

计算机视觉与模式识别 · 计算机科学 2022-05-23 Xiuxiu Bai , Zhe Liu , Yao Gao , Bin Liu , Yongqiang Hao

Recent work suggests goal-driven training of neural networks can be used to model neural activity in the brain. While response properties of neurons in artificial neural networks bear similarities to those in the brain, the network…

神经元与认知 · 定量生物学 2020-05-19 Christopher J. Cueva , Peter Y. Wang , Matthew Chin , Xue-Xin Wei

High-dimensional neural activity often reside in a low-dimensional subspace, referred to as neural manifolds. Grid cells in the medial entorhinal cortex provide a periodic spatial code that are organized near a toroidal manifold,…

神经元与认知 · 定量生物学 2025-10-22 Yuxing Jared Yao , Iris H. R. Yoon

Learning in the space-time domain remains a very challenging problem in machine learning and computer vision. Current computational models for understanding spatio-temporal visual data are heavily rooted in the classical single-image based…

计算机视觉与模式识别 · 计算机科学 2020-05-26 Andrei Nicolicioiu , Iulia Duta , Marius Leordeanu

The discovery of place cells and other spatially modulated neurons in the hippocampal complex of rodents has been crucial to elucidating the neural basis of spatial cognition. More recently, the replay of neural sequences encoding…

神经元与认知 · 定量生物学 2023-01-18 Adedapo Alabi , Dieter Vanderelst , Ali Minai

Grid cells in the brain respond when an animal occupies a periodic lattice of "grid fields" during spatial navigation. The grid scale varies along the dorso-ventral axis of the entorhinal cortex. We propose that the grid system minimizes…

神经元与认知 · 定量生物学 2018-05-14 Xue-Xin Wei , Jason Prentice , Vijay Balasubramanian

Place cells in the hippocampus are active when an animal visits a certain location (referred to as a place field) within an environment. Grid cells in the medial entorhinal cortex (MEC) respond at multiple locations, with firing fields that…

神经元与认知 · 定量生物学 2018-05-17 David M. Schwartz , O. Ozan Koyluoglu

In this paper we explain the strikingly regular activity of the 'grid' cells in rodent dorsal medial entorhinal cortex (dMEC) and the spatially localized activity of the hippocampal place cells in CA3 and CA1 by assuming that the…

神经元与认知 · 定量生物学 2008-04-22 Andras Lorincz , Melinda Kiszlinger , Gabor Szirtes

Deep reinforcement learning agents are often fragile while humans remain adaptive and flexible to varying scenarios. To bridge this gap, we present EDEN, a biologically inspired navigation framework that integrates learned entorhinal-like…

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