相关论文: Prediction of Turbulent Shear Stresses through Dys…
Heart disease is one of leading causes of mortality worldwide. Healthy heart valves are key for proper heart function. When these valves dysfunction, a replacement is often necessary in severe cases. The current study presents an…
Mechanical heart valve replacement is the preferred alternative in younger patients with severe symptomatic aortic valve disease. However, thrombus and pannus formations are common complications associated with bileaflet mechanical heart…
Bileaflet mechanical heart valves have one of the most successful valve designs for more than 30 years. These valves are often used for aortic valve replacement, where the geometry of the aortic root sinuses may vary due to valvular disease…
An experimental study is reported which investigates the wall shear stress (WSS) distribution in a transparent model of the human aorta comparing a bileaflet mechanical heart valve (BMHV) with a trileaflet mechanical heart valve (TMHV) in…
Cardiac disease and clinical intervention may both lead to an increased risk for thrombosis events due to modified blood flow in the heart, and thereby a change in the mechanical stimuli of blood cells passing through the chambers of the…
Pulsatile flow through compressed or defective blood vessels is a topic of fundamental importance in hemodynamics, particularly in cardiovascular research. This study examines flow dynamics within a tube with a bipolar cross section,…
This study employs extensive three-dimensional direct numerical simulations (DNS) to investigate the influence of blood non-Newtonian behaviors on the hemodynamics around a bileaflet mechanical heart valve under both steady inflow and…
Pulsating flows through tubular geometries are laminar provided that velocities are moderate. This in particular is also believed to apply to cardiovascular flows where inertial forces are typically too low to sustain turbulence. On the…
Albeit the hemodynamics of artificial heart valves has been investigated for several decades, the local shear-induced activation potential and subsequent transport phenomena of activated platelets in different valve designs, which mediate…
We present a systematic numerical study of the effect of turbulent velocity fluctuations on the thermal pressure distribution in thermally bistable flows. The simulations employ a random turbulent driving generated in Fourier space rather…
We report computational results of blood flow through a model of the human aortic arch and a vessel of actual diameter and length. On the top of the aortic arch the branching of the %%three arteries are included: the subclavian and jugular.…
The aortic valve is a three-leaflet passive structure that, driven by pressure differences between the left ventricle and the aorta, opens and closes during the heartbeat to ensure the correct stream direction and flow rate. In elderly…
Purpose: The mechanics of the mitral valve leaflet as a nonlinear, inelastic and anisotropic soft tissue results from an integrated response of many mathematical/physical indexes' that illustrate the tissue. In the past decade, finite…
The objective of this paper is to unravel any relations that may exist between turbulent shear flows and statistical mechanics, through a detailed numerical investigation in the simplest case where both can be well defined. The shear flow…
We numerically investigate the influence of flow development on secondary flow patterns and subsequent wall shear stress distributions in a curved artery model, and we compute vascular metrics commonly used to assess variations in blood…
Valvular heart diseases are growing concern in impoverished parts of the world, such as Southern-Africa, claiming more than 31 % of total deaths related to cardiovascular diseases. The ability to model the effects of regurgitant and…
Existing hemolysis algorithms are often constructed for laminar flows that expose red blood cells to a constant rate of shear. It remains an open question whether such models are applicable to turbulent flows, where there is a significant…
A microfluidic approach to probing the first normal stress difference from single-point pressure measurements in transient shear flows is presented. Using an original experimental design, we examine the near-zero-mean pulsatile flow of…
Bicuspid aortic valve is the most common congenital heart defect, affecting 1-2% of the global population. Patients with bicuspid valves frequently develop dilation and aneurysms of the ascending aorta. Both hemodynamic and genetic factors…
In this study OpenFOAM 4.4.2 was used to investigate flow inside the coronary artery of the heart. This step is the first step of our future project, which is to include conjugate heat transfer of the heart with three main coronary…