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This paper reports on the use of a convolutional neural network (CNN) methodology to analyse fluorescence images of calcium-ion Coulomb crystals in the gas phase. A transfer-learning approach is adopted using the publicly available RESNET50…

Calcium imaging has become a fundamental neural imaging technique, aiming to recover the individual activity of hundreds of neurons in a cortical region. Current methods (mostly matrix factorization) are aimed at detecting neurons in the…

应用统计 · 统计学 2019-02-11 Gal Mishne , Adam S. Charles

Calcium imaging is one of the most important tools in neurophysiology as it enables the observation of neuronal activity for hundreds of cells in parallel and at single-cell resolution. In order to use the data gained with calcium imaging,…

神经元与认知 · 定量生物学 2020-04-07 Elke Kirschbaum , Alberto Bailoni , Fred A. Hamprecht

Neurons encode information about the environment through their activity. As animals explore the environment, neurons rapidly acquire selectivity for distinct features of the external world; characterizing how these selectivity patterns…

Calcium imaging allows for the parallel measurement of large neuronal populations in a spatially resolved and minimally invasive manner, and has become a gold-standard for neuronal functionality. While deep generative models have been…

神经元与认知 · 定量生物学 2025-10-02 Berta Ros , Mireia Olives-Verger , Caterina Fuses , Josep M Canals , Jordi Soriano , Jordi Abante

Visual saliency detection aims at identifying the most visually distinctive parts in an image, and serves as a pre-processing step for a variety of computer vision and image processing tasks. To this end, the saliency detection procedure…

计算机视觉与模式识别 · 计算机科学 2017-02-27 Xuanyang Xi , Yongkang Luo , Fengfu Li , Peng Wang , Hong Qiao

With the rapid growth of neuroimaging technologies, a great effort has been dedicated recently to investigate the dynamic changes in brain activity. Examples include time course calcium imaging and dynamic brain functional connectivity. In…

统计方法学 · 统计学 2020-08-31 Wei Hu , Tianyu Pan , Dehan Kong , Weining Shen

Creating datasets for Neuromorphic Vision is a challenging task. A lack of available recordings from Neuromorphic Vision sensors means that data must typically be recorded specifically for dataset creation rather than collecting and…

数据库 · 计算机科学 2015-10-20 Garrick Orchard , Ajinkya Jayawant , Gregory Cohen , Nitish Thakor

Neural recordings, returns from radars and sonars, images in astronomy and single-molecule microscopy can be modeled as a linear superposition of a small number of scaled and delayed copies of a band-limited or diffraction-limited point…

信息论 · 计算机科学 2016-05-25 Yuejie Chi

Deducing the structure of neural circuits is one of the central problems of modern neuroscience. Recently-introduced calcium fluorescent imaging methods permit experimentalists to observe network activity in large populations of neurons,…

应用统计 · 统计学 2011-07-22 Yuriy Mishchencko , Joshua T. Vogelstein , Liam Paninski

We study the question of extracting a sequence of functions $\{\boldsymbol{f}_i, \boldsymbol{g}_i\}_{i=1}^s$ from observing only the sum of their convolutions, i.e., from $\boldsymbol{y} = \sum_{i=1}^s \boldsymbol{f}_i\ast…

信息论 · 计算机科学 2017-11-29 Shuyang Ling , Thomas Strohmer

In this work, we propose a simple yet effective solution to the problem of connectome inference in calcium imaging data. The proposed algorithm consists of two steps. First, processing the raw signals to detect neural peak activities.…

We propose a deconvolution algorithm for images blurred and degraded by a Poisson noise. The algorithm uses a fast proximal backward-forward splitting iteration. This iteration minimizes an energy which combines a \textit{non-linear} data…

应用统计 · 统计学 2008-12-18 François-Xavier Dupé , Jalal Fadili , Jean Luc Starck

We study noisy calcium imaging data, with a focus on the classification of spike traces. As raw traces obscure the true temporal structure of neuron's activity, we performed a tuned filtering of the calcium concentration using two methods:…

神经元与认知 · 定量生物学 2024-09-17 Arianna Burzacchi , Nicoletta D'Angelo , David Payares-Garcia , Jorge Mateu

As the availability of imagery data continues to swell, so do the demands on transmission, storage and processing power. Processing requirements to handle this plethora of data is quickly outpacing the utility of conventional processing…

计算机视觉与模式识别 · 计算机科学 2022-11-01 Artyom M. Grigoryan , Sos S. Agaian , Karen Panetta

Ultra-low power local signal processing is a crucial aspect for edge applications on always-on devices. Neuromorphic processors emulating spiking neural networks show great computational power while fulfilling the limited power budget as…

机器学习 · 计算机科学 2021-11-03 Philipp Weidel , Sadique Sheik

Confocal laser-scanning microscopy (CLSM) is one of the most popular optical architectures for fluorescence imaging. In CLSM, a focused laser beam excites the fluorescence emission from a specific specimen position. Some actuators scan the…

图像与视频处理 · 电气工程与系统科学 2023-05-10 Alessandro Zunino , Marco Castello , Giuseppe Vicidomini

High-speed optical imaging of dynamic neuronal activity is essential yet challenging in neuroscience. While calcium imaging has been firmly established as a workhorse technique for monitoring neuronal activity, its limited temporal…

Blind deconvolution is a challenging problem, but in low-light it is even more difficult. Existing algorithms, both classical and deep-learning based, are not designed for this condition. When the photon shot noise is strong, conventional…

图像与视频处理 · 电气工程与系统科学 2022-11-21 Yash Sanghvi , Abhiram Gnanasambandam , Zhiyuan Mao , Stanley H. Chan

In this paper, we propose a novel design of image deblurring in the form of one-shot convolution filtering that can directly convolve with naturally blurred images for restoration. The problem of optical blurring is a common disadvantage to…

图像与视频处理 · 电气工程与系统科学 2019-07-22 Mahdi S. Hosseini , Konstantinos N. Plataniotis