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Advances in laser and optoelectronic technologies brought the general concept of optomechanical manipulation to the level of standard biophysical tools, paving ways towards controlled experiments and measurements of tiny mechanical forces.…

光学 · 物理学 2021-06-30 Ivan Shishkin , Hen Markovich , Yael Roichman , Pavel Ginzburg

Investigations of free-standing liquid films enjoy an increasing popularity due to their relevance for many fundamental and applied scientific problems. They constitute soap bubbles and foams, serve as membranes for gas transport or as…

Artificial Intelligence (AI) and Machine Learning (ML) are weaving their way into the fabric of society, where they are playing a crucial role in numerous facets of our lives. As we witness the increased deployment of AI and ML in various…

Visual Molecular Dynamics (VMD) is one of the most widely used molecular graphics software in the community of theoretical simulations. So far, however, it still lacks a graphical user interface (GUI) for molecular manipulations when doing…

生物大分子 · 定量生物学 2020-07-03 ChenChen Wu , Shengtang Liu , Shitong Zhang , Zaixing Yang

The human-associated microbiome is closely tied to human health and is of substantial clinical interest. Metagenomics-based tools are emerging for clinical diagnostics, tracking the spread of diseases, and surveillance of potential…

In electrophysiology, multielectrode array devices (MEA) are the gold standard for the study of large ensambles of electrogenic cells. In the last decades, thanks to the adoption of nanotechnologies, the study of physiological and…

生物物理 · 物理学 2023-01-24 Giulia Bruno

In this article, we show a novel approach to implementing valving action in a dynamically evolving capillary filling process, by exploiting alternating current electrothermal (ACET) mechanism. The surfaces of the top and bottom walls of the…

流体动力学 · 物理学 2018-04-19 Golak Kunti , Debabrata DasGupta , Anandaroop Bhattacharya , Suman Chakraborty

Dream of developing molecule-based logic and memory device is more than 70-year-old. Presently, molecule-based devices are also considered for quantum computation hardware. The recent studies have shown the molecule connected to metal leads…

材料科学 · 物理学 2019-12-04 Pawan Tyagi , Edwards Friebe , Collin Baker

This paper studies cooperative schemes for the inter-cell interference control in orthogonal-frequency-divisionmultiple- access (OFDMA) cellular systems. The downlink transmission in a simplified two-cell system is examined, where both…

信息论 · 计算机科学 2011-02-18 Bin Da , Rui Zhang

Significant progress has been made to increase access to droplet microfluidics for labs with limited microfluidics expertise or fabrication equipment. In particular, using off-the-shelf systems has been a valuable approach. However, the…

Portable electronic devices are already an indispensable part of our daily life; and their increasing number and demand for higher performance is becoming a challenge for the research community. In particular, a major concern is the way to…

应用物理 · 物理学 2017-12-06 Francesco Chiabrera , Iñigo Garbayo , Nerea Alayo , Albert Tarancón

Colloidal lithography [1] is how patterns are reproduced in a variety of natural systems and is used more and more as an efficient fabrication tool in bio-, opto-, and nano-technology. Nanoparticles in the colloid are made to form a mask on…

介观与纳米尺度物理 · 物理学 2013-11-27 A. Iovan , M. Fischer , R. Lo Conte , V. Korenivski

We give an explicit formula for the membrane potential of cells in terms of the intracellular and extracellular ionic concentrations, and derive equations for the ionic currents that flow through channels, exchangers and electrogenic pumps.…

生物物理 · 物理学 2007-05-23 L. P. Endresen , K. Hall , J. S. Hoye , J. Myrheim

Precise manipulation of fluids and objects on the micro scale is seldom a simple task, but nevertheless crucial for many applications in life sciences and chemical engineering. We present a microfluidic chip fabricated in silicon-glass,…

流体动力学 · 物理学 2023-02-22 Alen Pavlic , Cooper Lars Harshbarger , Luca Rosenthaler , Jess Gerrit Snedeker , Jürg Dual

The use of embedded software is advancing in modern medical devices, so does its capabilities and complexity. This paradigm shift brings many challenges such as an increased rate of medical device failures due to software faults. In this…

软件工程 · 计算机科学 2017-06-21 Atif Mashkoor , Miklos Biro

In processes such as embryo shaping, wound healing, and malignant cell invasion, epithelial cells transition between dispersed phases, where the cells move independently, and condensed phases, where they aggregate and deform to close gaps,…

软凝聚态物质 · 物理学 2024-09-25 Anshuman Pasupalak , Zeng Wu , Massimo Pica Ciamarra

The effects of cell size and deformability on the lateral migration and deformation of living cells flowing through a rectangular microchannel has been numerically investigated and compared with the inertial-microfluidics data on detection…

流体动力学 · 物理学 2013-06-21 Hongzhi Lan , Soojung Claire Hur , Dino Di Carlo , Damir B. Khismatullin

The turn of the millennium has seen a growing interest in the study of live cells by infrared (IR) spectroscopy, driven by the versatility, wealth of molecular information, and potential for high-throughput screening of the technique.…

定量方法 · 定量生物学 2025-11-11 Luca Quaroni

Recently developed technologies to generate single-cell genomic data have made a revolutionary impact in the field of biology. Multi-omics assays offer even greater opportunities to understand cellular states and biological processes.…

基因组学 · 定量生物学 2022-01-19 Stefan Stanojevic , Yijun Li , Lana X. Garmire

We describe and characterize a device for alkali vapor pressure modulation on the 100ms timescale in a single-cell cold atom experiment. Its mechanism is based on optimized heat conduction between a current-modulated alkali dispenser and a…

原子物理 · 物理学 2014-08-25 Vincent Dugrain , Peter Rosenbusch , Jakob Reichel
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