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In document-level event extraction (DEE) task, event arguments always scatter across sentences (across-sentence issue) and multiple events may lie in one document (multi-event issue). In this paper, we argue that the relation information of…

计算与语言 · 计算机科学 2022-06-08 Yuan Liang , Zhuoxuan Jiang , Di Yin , Bo Ren

Meta-analysis is a powerful tool for assessing drug safety by combining treatment-related toxicological findings across multiple studies, as clinical trials are typically underpowered for detecting adverse drug effects. However, incomplete…

统计方法学 · 统计学 2024-02-12 Xinyue Qi , Shouhao Zhou , Christine B. Peterson , Yucai Wang , Xinying Fang , Michael L. Wang , Chan Shen

Event extraction requires high-quality expert human annotations, which are usually expensive. Therefore, learning a data-efficient event extraction model that can be trained with only a few labeled examples has become a crucial challenge.…

计算与语言 · 计算机科学 2022-05-05 I-Hung Hsu , Kuan-Hao Huang , Elizabeth Boschee , Scott Miller , Prem Natarajan , Kai-Wei Chang , Nanyun Peng

When patients need to take medicine, particularly taking more than one kind of drug simultaneously, they should be alarmed that there possibly exists drug-drug interaction. Interaction between drugs may have a negative impact on patients or…

计算与语言 · 计算机科学 2020-08-31 Siliang Tang , Qi Zhang , Tianpeng Zheng , Mengdi Zhou , Zhan Chen , Lixing Shen , Xiang Ren , Yueting Zhuang , Shiliang Pu , Fei Wu

Joint entity and relation extraction is the fundamental task of information extraction, consisting of two subtasks: named entity recognition and relation extraction. However, most existing joint extraction methods suffer from issues of…

计算与语言 · 计算机科学 2024-03-28 Wenjun Kong , Yamei Xia

Adverse drug reaction (ADR) prediction plays a crucial role in both health care and drug discovery for reducing patient mortality and enhancing drug safety. Recently, many studies have been devoted to effectively predict the drug-ADRs…

信息检索 · 计算机科学 2023-08-08 Haoxuan Li , Taojun Hu , Zetong Xiong , Chunyuan Zheng , Fuli Feng , Xiangnan He , Xiao-Hua Zhou

Fully understanding narratives often requires identifying events in the context of whole documents and modeling the event relations. However, document-level event extraction is a challenging task as it requires the extraction of event and…

计算与语言 · 计算机科学 2021-05-11 Kung-Hsiang Huang , Nanyun Peng

Adversarial attacks are a type of attack on machine learning models where an attacker deliberately modifies the inputs to cause the model to make incorrect predictions. Adversarial attacks can have serious consequences, particularly in…

Adverse Drug Reaction (ADR) is a significant public health concern world-wide. Numerous graph-based methods have been applied to biomedical graphs for predicting ADRs in pre-marketing phases. ADR detection in post-market surveillance is no…

机器学习 · 计算机科学 2020-04-02 Heeyoung Kwak , Minwoo Lee , Seunghyun Yoon , Jooyoung Chang , Sangmin Park , Kyomin Jung

Definition Extraction (DE) is one of the well-known topics in Information Extraction that aims to identify terms and their corresponding definitions in unstructured texts. This task can be formalized either as a sentence classification task…

计算与语言 · 计算机科学 2020-05-01 Amir Pouran Ben Veyseh , Franck Dernoncourt , Dejing Dou , Thien Huu Nguyen

Complex or co-existing diseases are commonly treated using drug combinations, which can lead to higher risk of adverse side effects. The detection of polypharmacy side effects is usually done in Phase IV clinical trials, but there are still…

机器学习 · 统计学 2019-05-03 Andreea Deac , Yu-Hsiang Huang , Petar Veličković , Pietro Liò , Jian Tang

Adverse drug interactions are largely preventable causes of medical accidents, which frequently result in physician and emergency room encounters. The detection of drug interactions in a lab, prior to a drug's use in medical practice, is…

机器学习 · 计算机科学 2023-02-08 Bar Vered , Guy Shtar , Lior Rokach , Bracha Shapira

Medication adherence is a well-known problem for pharmaceutical treatment of chronic diseases. Understanding how nonadherence affects treatment efficacy is made difficult by the ethics of clinical trials that force patients to skip doses of…

定量方法 · 定量生物学 2021-12-30 Elijah D Counterman , Sean D Lawley

The primary goal of drug safety researchers and regulators is to promptly identify adverse drug reactions. Doing so may in turn prevent or reduce the harm to patients and ultimately improve public health. Evaluating and monitoring drug…

计算与语言 · 计算机科学 2022-10-25 Zhaoyue Sun , Jiazheng Li , Gabriele Pergola , Byron C. Wallace , Bino John , Nigel Greene , Joseph Kim , Yulan He

Biomedical Event Extraction (BEE) is a challenging task that involves modeling complex relationships between fine-grained entities in biomedical text. BEE has traditionally been formulated as a classification problem. With recent…

计算与语言 · 计算机科学 2025-02-24 Haohan Yuan , Siu Cheung Hui , Haopeng Zhang

In the realm of cancer treatment, summarizing adverse drug events (ADEs) reported by patients using prescribed drugs is crucial for enhancing pharmacovigilance practices and improving drug-related decision-making. While the volume and…

计算与语言 · 计算机科学 2025-05-08 Sofia Jamil , Aryan Dabad , Bollampalli Areen Reddy , Sriparna Saha , Rajiv Misra , Adil A. Shakur

Medical Relation Extraction (MRE) task aims to extract relations between entities in medical texts. Traditional relation extraction methods achieve impressive success by exploring the syntactic information, e.g., dependency tree. However,…

计算与语言 · 计算机科学 2022-08-30 Yifan Jin , Jiangmeng Li , Zheng Lian , Chengbo Jiao , Xiaohui Hu

Biomedical event extraction is critical in understanding biomolecular interactions described in scientific corpus. One of the main challenges is to identify nested structured events that are associated with non-indicative trigger words. We…

计算与语言 · 计算机科学 2020-10-13 Kung-Hsiang Huang , Mu Yang , Nanyun Peng

Event extraction is an important work of medical text processing. According to the complex characteristics of medical text annotation, we use the end-to-end event extraction model to enhance the output formatting information of events.…

计算与语言 · 计算机科学 2022-08-22 Wei Feng , Ruochen Huang , Yun Yu , Huiting Sun , Yun Liu

Adverse drug reactions considerably impact patient outcomes and healthcare costs in cancer therapy. Using artificial intelligence to predict adverse drug reactions in real time could revolutionize oncology treatment. This study aims to…

定量方法 · 定量生物学 2025-05-21 Fatma Zahra Abdeldjouad , Menaouer Brahami , Mohammed Sabri