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Dynamic treatment regimes are sequential decision rules that adapt treatment according to individual time-varying characteristics and outcomes to achieve optimal effects, with applications in precision medicine, personalized…

统计方法学 · 统计学 2025-10-24 Yuanshan Gao , Yang Bai , Yifan Cui

A common concern when a policymaker draws causal inferences from and makes decisions based on observational data is that the measured covariates are insufficiently rich to account for all sources of confounding, i.e., the standard no…

统计方法学 · 统计学 2023-10-25 Tao Shen , Yifan Cui

The traditional k nearest neighbor (kNN) approach uses a distance formula within a spherical region to determine the k closest training observations to a test sample point. However, this approach may not work well when test point is located…

机器学习 · 统计学 2024-02-19 Amjad Ali , Zardad Khan , Dost Muhammad Khan , Saeed Aldahmani

Algorithms often carry out equally many computations for "easy" and "hard" problem instances. In particular, algorithms for finding nearest neighbors typically have the same running time regardless of the particular problem instance. In…

数据结构与算法 · 计算机科学 2020-03-25 Daniel LeJeune , Richard G. Baraniuk , Reinhard Heckel

We develop a mathematical framework to define an optimal individualized treatment rule (ITR) within the context of prioritized outcomes in a randomized controlled trial. Our optimality criterion is based on the framework of generalized…

统计方法学 · 统计学 2025-06-17 François Petit , Gérard Biau , Raphaël Porcher

We study the consistency of the $k$-nearest neighbor regressor under complex survey designs. While consistency results for this algorithm are well established for independent and identically distributed data, corresponding results for…

机器学习 · 统计学 2026-03-19 Caren Hasler

Treatment effect estimation is of high-importance for both researchers and practitioners across many scientific and industrial domains. The abundance of observational data makes them increasingly used by researchers for the estimation of…

机器学习 · 统计学 2023-06-22 Niki Kiriakidou , Christos Diou

The $k$-nearest neighbor ($k$-NN) algorithm is one of the most popular methods for nonparametric classification. However, a relevant limitation concerns the definition of the number of neighbors $k$. This parameter exerts a direct impact on…

机器学习 · 计算机科学 2024-09-10 Alexandre Luís Magalhães Levada , Frank Nielsen , Michel Ferreira Cardia Haddad

Precision medicine is currently a topic of great interest in clinical and intervention science. One way to formalize precision medicine is through a treatment regime, which is a sequence of decision rules, one per stage of clinical…

统计方法学 · 统计学 2016-06-07 Yichi Zhang , Eric B. Laber , Anastasios Tsiatis , Marie Davidian

The weighted k-nearest neighbors algorithm is one of the most fundamental non-parametric methods in pattern recognition and machine learning. The question of setting the optimal number of neighbors as well as the optimal weights has…

机器学习 · 统计学 2017-01-26 Oren Anava , Kfir Y. Levy

Trustworthiness in model predictions is crucial for safety-critical applications in the real world. However, deep neural networks often suffer from the issues of uncertainty estimation, such as miscalibration. In this study, we propose…

计算与语言 · 计算机科学 2025-02-07 Wataru Hashimoto , Hidetaka Kamigaito , Taro Watanabe

A dynamic treatment regime is a sequence of treatment decision rules tailored to an individual's evolving status over time. In precision medicine, much focus has been placed on finding an optimal dynamic treatment regime which, if followed…

其他统计学 · 统计学 2025-10-13 Chunyu Wang , Brian DM Tom

Considerable recent work has focused on methods for analyzing experiments which exhibit treatment interference -- that is, when the treatment status of one unit may affect the response of another unit. Such settings are common in…

统计方法学 · 统计学 2023-07-31 Samirah Alzubaidi , Michael J. Higgins

The k-nearest-neighbor method performs classification tasks for a query sample based on the information contained in its neighborhood. Previous studies into the k-nearest-neighbor algorithm usually achieved the decision value for a class by…

机器学习 · 计算机科学 2018-12-10 Chengsheng Mao , Bin Hu , Lei Chen , Philip Moore , Xiaowei Zhang

Precision medicine involves developing individualized treatment regimes (ITRs) which allow for treatment decisions to be tailored to patient characteristics. Naturally, the identification of the optimal regime, that is, the rule which…

统计方法学 · 统计学 2025-09-30 Misha Dolmatov , Erica E. M. Moodie , David A. Stephens , Dipankar Bandyopadhyay

A treatment regime is a function that maps individual patient information to a recommended treatment, hence explicitly incorporating the heterogeneity in need for treatment across individuals. Patient responses are dichotomous and can be…

机器学习 · 统计学 2016-07-07 Yingfei Wang , Warren Powell

Nearest neighbor is a popular class of classification methods with many desirable properties. For a large data set which cannot be loaded into the memory of a single machine due to computation, communication, privacy, or ownership…

机器学习 · 统计学 2019-11-01 Xingye Qiao , Jiexin Duan , Guang Cheng

The k Nearest Neighbors (kNN) method has received much attention in the past decades, where some theoretical bounds on its performance were identified and where practical optimizations were proposed for making it work fairly well in high…

机器学习 · 计算机科学 2016-06-14 Aleksander Lodwich , Faisal Shafait , Thomas Breuel

k Nearest Neighbor (kNN) method is a simple and popular statistical method for classification and regression. For both classification and regression problems, existing works have shown that, if the distribution of the feature vector has…

统计理论 · 数学 2019-10-24 Puning Zhao , Lifeng Lai

Nearest neighbor methods are a popular class of nonparametric estimators with several desirable properties, such as adaptivity to different distance scales in different regions of space. Prior work on convergence rates for nearest neighbor…

机器学习 · 计算机科学 2014-07-03 Kamalika Chaudhuri , Sanjoy Dasgupta
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