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Contact-tracing is an essential tool in order to mitigate the impact of pandemic such as the COVID-19. In order to achieve efficient and scalable contact-tracing in real time, digital devices can play an important role. While a lot of…

Many real-world functions are defined over both categorical and category-specific continuous variables and thus cannot be optimized by traditional Bayesian optimization (BO) methods. To optimize such functions, we propose a new method that…

机器学习 · 计算机科学 2019-12-02 Dang Nguyen , Sunil Gupta , Santu Rana , Alistair Shilton , Svetha Venkatesh

We address the problem of best arm identification (BAI) with a fixed budget for two-armed Gaussian bandits. In BAI, given multiple arms, we aim to find the best arm, an arm with the highest expected reward, through an adaptive experiment.…

机器学习 · 计算机科学 2024-03-19 Masahiro Kato

Accurate and reliable predictions of infectious disease dynamics can be valuable to public health organizations that plan interventions to decrease or prevent disease transmission. A great variety of models have been developed for this…

机器学习 · 统计学 2018-07-04 Evan L. Ray , Nicholas G. Reich

Combating an epidemic entails finding a plan that describes when and how to apply different interventions, such as mask-wearing mandates, vaccinations, school or workplace closures. An optimal plan will curb an epidemic with minimal loss of…

机器学习 · 计算机科学 2023-06-08 Anh Mai , Nikunj Gupta , Azza Abouzied , Dennis Shasha

We aim to efficiently allocate a fixed simulation budget to identify the top-mc designs for each context among a finite number of contexts. The performance of each design under a context is measured by an identifiable statistical…

统计方法学 · 统计学 2023-07-03 Xinbo Shi , Yijie Peng , Gongbo Zhang

Recent pandemics have highlighted the critical role of infectious disease models in guiding public health decision-making, driving demand for realistic models that can provide timely answers under uncertainty. Compartmental models are…

统计方法学 · 统计学 2026-03-18 Xiahui Li , Fergus J. Chadwick , Ben Swallow

The threat of avian influenza and the 2004-2005 influenza vaccine supply shortage in the United States has sparked a debate about optimal vaccination strategies to reduce the burden of morbidity and mortality caused by the influenza virus.…

种群与进化 · 定量生物学 2010-02-10 Shweta Bansal , Babak Pourbohloul , Lauren Ancel Meyers

Thompson sampling is a popular algorithm for solving multi-armed bandit problems, and has been applied in a wide range of applications, from website design to portfolio optimization. In such applications, however, the number of choices (or…

统计方法学 · 统计学 2021-01-19 Simon Mak , Yuanshuo Zhou , Lavonne Hoang , C. F. Jeff Wu

Epidemic risk assessment poses inherent challenges, with traditional approaches often failing to balance health outcomes and economic constraints. This paper presents a data-driven decision support tool that models epidemiological dynamics…

应用统计 · 统计学 2025-11-24 Chang Zhai , Ping Chen , Zhuo Jin , David Pitt

Epidemics of infectious diseases are an important threat to public health and global economies. Yet, the development of prevention strategies remains a challenging process, as epidemics are non-linear and complex processes. For this reason,…

We study the problem of finding the optimal dosage in early stage clinical trials through the multi-armed bandit lens. We advocate the use of the Thompson Sampling principle, a flexible algorithm that can accommodate different types of…

机器学习 · 统计学 2020-04-09 Maryam Aziz , Emilie Kaufmann , Marie-Karelle Riviere

The computational costs of inference and planning have confined Bayesian model-based reinforcement learning to one of two dismal fates: powerful Bayes-adaptive planning but only for simplistic models, or powerful, Bayesian non-parametric…

人工智能 · 计算机科学 2014-02-11 Arthur Guez , David Silver , Peter Dayan

Accurate epidemic forecasting is critical for effective public health interventions. This study compares Bayesian and Frequentist estimation frameworks within deterministic compartmental epidemic models, focusing on nonlinear least squares…

定量方法 · 定量生物学 2025-09-09 Hamed Karami , Ruiyan Luo , Pejman Sanaei , Gerardo Chowell

Many epidemic models are naturally defined as individual-based models: where we track the state of each individual within a susceptible population. Inference for individual-based models is challenging due to the high-dimensional state-space…

统计方法学 · 统计学 2025-08-04 Lorenzo Rimella , Christopher Jewell , Paul Fearnhead

Best arm identification (BAI) aims to identify the highest-performance arm among a set of $K$ arms by collecting stochastic samples from each arm. In real-world problems, the best arm needs to satisfy additional feasibility constraints.…

机器学习 · 计算机科学 2026-01-26 Ting Cai , Kirthevasan Kandasamy

Understanding age-group dynamics of infectious diseases is a fundamental issue for both scientific study and policymaking. Age-structure epidemic models were developed in order to study and improve our understanding of these dynamics. By…

种群与进化 · 定量生物学 2019-11-22 Rami Yaari , Amit Huppert , Itai Dattner

Efficient testing and vaccination protocols are critical aspects of epidemic management. To study the optimal allocation of limited testing and vaccination resources in a heterogeneous contact network of interacting susceptible, recovered,…

种群与进化 · 定量生物学 2026-05-12 Mingtao Xia , Lucas Böttcher , Tom Chou

Public health surveillance systems often fail to detect emerging infectious diseases, particularly in resource limited settings. By integrating relevant clinical and internet-source data, we can close critical gaps in coverage and…

应用统计 · 统计学 2019-03-05 Kai Liu , Ravi Srinivasan , Lauren Ancel Meyers

Thompson Sampling algorithm is a well known Bayesian algorithm for solving stochastic multi-armed bandit. At each time step the algorithm chooses each arm with probability proportional to it being the current best arm. We modify the…

机器学习 · 计算机科学 2017-10-09 Qiang Ha