相关论文: Gene Ontology (GO) Prediction using Machine Learni…

The Gene Ontology (GO) provides biologists with a controlled terminology that describes how genes are associated with functions and how functional terms are related to each other. These term-term relationships encode how scientists conceive…

It is important to develop sustainable processes in materials science and manufacturing that are environmentally friendly. AI can play a significant role in decision support here as evident from our earlier research leading to tools…

Reinforcement Learning (RL) has demonstrated significant potential in certain real-world industrial applications, yet its broader deployment remains limited by inherent challenges such as sample inefficiency and unstable learning dynamics.…

Hyperparameter optimization is a challenging problem in developing deep neural networks. Decision of transfer layers and trainable layers is a major task for design of the transfer convolutional neural networks (CNN). Conventional transfer…

Convolutional Neural Networks (CNNs) have gained a significant attraction in the recent years due to their increasing real-world applications. Their performance is highly dependent to the network structure and the selected optimization…

Machine-learning models that learn from data to predict how protein sequence encodes function are emerging as a useful protein engineering tool. However, when using these models to suggest new protein designs, one must deal with the vast…

We introduce a novel reinforcement learning algorithm (AGRO, for Any-Generation Reward Optimization) for fine-tuning large-language models. AGRO leverages the concept of generation consistency, which states that the optimal policy satisfies…

All living organisms use the same genetic languages in their molecular biology machinery. They can be understood as the optimal solutions to the replication tasks involving DNA and proteins. These solutions perfectly fit the pattern…

Metal-organic frameworks (MOFs) have emerged as promising materials for various applications due to their unique structural properties and versatile functionalities. This study presents a comprehensive investigation of machine learning…

Genetic algorithm (GA) is typically used to solve nonlinear model predictive control's optimization problem. However, the size of the search space in which the GA searches for the optimal control inputs is crucial for its applicability to…

Genetic algorithms (GAs) have a long history of over four decades. GAs are adaptive heuristic search algorithms that provide solutions for optimization and search problems. The GA derives expression from the biological terminology of…

This paper describes a methodology for analyzing the evolutionary dynamics of genetic programming (GP) using genealogical information, diversity measures and information about the fitness variation from parent to offspring. We introduce a…

Next Generation Sequencing can sample the whole genome (WGS) or the 1-2% of the genome that codes for proteins called the whole exome (WES). Machine learning approaches to variant calling achieve high accuracy in WGS data, but the reduced…

In this dissertation, we present a generative model to capture the relation between facial image quality features (like pose, illumination direction, etc) and face recognition performance. Such a model can be used to predict the performance…

The impressive generalization performance of modern neural networks is attributed in part to their ability to implicitly memorize complex training patterns. Inspired by this, we explore a novel mechanism to improve model generalization via…

Background: Selecting feature genes to predict phenotypes is one of the typical tasks in analyzing genomics data. Though many general-purpose algorithms were developed for prediction, dealing with highly correlated genes in the prediction…

Here a genetic algorithm (GA) is presented that creates a teaching schedule for a university physics department by algorithmically assigning ${\sim}200$ classes to ${\sim}50$ professors for each of three academic terms per year. The…

A very active area of materials research is to devise methods that use machine learning to automatically extract predictive models from existing materials data. While prior examples have demonstrated successful models for some applications,…

Here, we use Machine Learning (ML) algorithms to update and improve the efficiencies of fitting GARCH model parameters to empirical data. We employ an Artificial Neural Network (ANN) to predict the parameters of these models. We present a…

We analyze algorithmic and computational aspects of biological phenomena, such as replication and programmed death, in the context of machine learning. We use two different measures of neuron efficiency to develop machine learning…