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Cells contain elaborate and interconnected networks of protein polymers which make up the cytoskeleton. The cytoskeleton governs the internal positioning and movement of vesicles and organelles, and controls dynamic changes in cell…

生物物理 · 物理学 2017-01-24 Lishibanya Mohapatra , Bruce L. Goode , Predrag Jelenkovic , Rob Phillips , Jane Kondev

The emergence of a body axis is a fundamental step in the development of multicellular organisms. In simple systems such as $\textit{Hydra}$, growing evidence suggests that mechanical forces generated by collective cellular activity play a…

软凝聚态物质 · 物理学 2026-01-09 Arthur Hernandez , Cuncheng Zhu , Luca Giomi

The mechanical behaviour and symmetry-breaking shape deformation of red blood cells subjected to shear flows is used to demonstrate that far from being random fluids, both the membrane and cytoplasm of every biological cell undergo…

综合物理 · 物理学 2007-05-23 Juanita Lofthouse

Ordered polarity alignment of a cell population plays a vital role in biology, such as in hair follicle alignment and asymmetric cell division. Here, we propose a theoretical framework for the understanding of generic dynamical properties…

斑图形成与孤子 · 物理学 2016-12-13 Kaori Sugimura , Hiroshi Kori

The structure, thermodynamics and slow activated dynamics of the equilibrated metastable regime of glass-forming fluids remains a poorly understood problem of high theoretical and experimental interest. We apply a highly accurate…

软凝聚态物质 · 物理学 2024-08-21 Subhashish Chaki , Baicheng Mei , Kenneth S. Schweizer

Recent work on particle-based models of tissues has suggested that any finite rate of cell division and cell death is sufficient to fluidize an epithelial tissue. At the same time, experimental evidence has indicated the existence of glassy…

软凝聚态物质 · 物理学 2019-05-07 Michael Czajkowski , Daniel M. Sussman , M. Cristina Marchetti , M. Lisa Manning

In order to describe two-dimensionally packed cells in epithelial tissues both mathematically and physically, there have been developed several sorts of geometrical models, such as the vertex model, the finite element model, the…

生物物理 · 物理学 2014-11-19 Yukitaka Ishimoto , Yoshihiro Morishita

Mechanical cues like the rigidity of the substrate are main determinants for the decision making of adherent cells. Here we use a mechano-chemical model to predict the cellular response to varying substrate stiffness. The model equations…

细胞行为 · 定量生物学 2010-07-08 A. Besser , U. S. Schwarz

Biological cells in soft materials can be modeled as anisotropic force contraction dipoles. The corresponding elastic interaction potentials are long-ranged ($\sim 1/r^3$ with distance $r$) and depend sensitively on elastic constants,…

软凝聚态物质 · 物理学 2009-11-07 U. S. Schwarz , S. A. Safran

Synchronization of actively oscillating organelles such as cilia and flagella facilitates self-propulsion of cells and pumping fluid in low Reynolds number environments. To understand the key mechanism behind synchronization induced by…

软凝聚态物质 · 物理学 2015-05-20 Nariya Uchida , Ramin Golestanian

Chemotaxis and haptotaxis have been a main theme in the macroscopic study of bacterial and cellular motility. In this work we investigate the influence these processes have on the shape and motility of fast migrating cells. We note that…

细胞行为 · 定量生物学 2016-12-08 Aaron Brunk , Niklas Kolbe , Nikolaos Sfakianakis

Cells swimming in confined environments are attracted by surfaces. We measure the steady-state distribution of smooth-swimming bacteria (Escherichia coli) between two glass plates. In agreement with earlier studies, we find a strong…

软凝聚态物质 · 物理学 2008-10-02 Allison P. Berke , Linda Turner , Howard C. Berg , Eric Lauga

Motile biological cells in tissue often display the phenomenon of durotaxis, i.e. they tend to move towards stiffer parts of substrate tissue. The mechanism for this behavior is not completely understood. We consider simplified models for…

生物物理 · 物理学 2019-01-03 Charles R. Doering , Xiaoming Mao , Leonard M. Sander

An adequate control of cell response in tissue engineering applications is of utmost importance to obtain products suitable to clinical practice. This paper is the first part of a series of two connected publications in which we study via…

组织与器官 · 定量生物学 2015-12-08 Chiara Lelli , Riccardo Sacco , Paola Causin , Manuela T. Raimondi

Self-propelled bacteria are marvels of nature with a potential to power dynamic materials and microsystems of the future. The challenge is in commanding their chaotic behavior. By dispersing swimming Bacillus subtilis in a…

软凝聚态物质 · 物理学 2016-12-21 Chenhui Peng , Taras Turiv , Yubing Guo , Qi-Huo Wei , Oleg D. Lavrentovich

We study the properties and symmetries governing the hydrodynamic interaction between two identical, arbitrarily shaped objects, driven through a viscous fluid. We treat analytically the leading (dipolar) terms of the pair-mobility matrix,…

流体动力学 · 物理学 2016-05-03 Tomer Goldfriend , Haim Diamant , Thomas A. Witten

Motility is a fundamental survival strategy of bacteria to navigate porous environments. Swimming cells thrive in quiescent wetlands and sediments at the bottom of the marine water column, where they mediate many essential biogeochemical…

软凝聚态物质 · 物理学 2022-01-11 Amin Dehkharghani , Nicolas Waisbord , Jeffrey S. Guasto

The macroscopic behaviour of active matter arises from nonequilibrium microscopic processes. In soft materials, active stresses typically drive macroscopic shape changes, which in turn alter the geometry constraining the microscopic…

软凝聚态物质 · 物理学 2024-11-26 Tim Dullweber , Roman Belousov , Anna Erzberger

The conditions under which biological cells switch from a static to a motile state are fundamental to the understanding of many healthy and pathological processes. In this paper, we show that even in the presence of a fully symmetric…

生物物理 · 物理学 2024-01-12 Jocelyn Étienne , Pierre Recho

Elastic channels are an important component of many soft matter systems, in which hydrodynamic interactions with confining membranes determine the behavior of particles in flow. In this work, we derive analytical expressions for the Green's…

流体动力学 · 物理学 2017-12-06 Abdallah Daddi-Moussa-Ider , Maciej Lisicki , Stephan Gekle