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Uncovering the rules governing the nonequilibrium dynamics of the membranes that define biological cells is of central importance to understanding the physics of living systems. We theoretically and computationally investigate the behavior…

Cell spreading and motility on an adhesive substrate are driven by the active physical forces generated by the actin cytoskeleton. We have recently shown that coupling curved membrane complexes to protrusive forces, exerted by the actin…

软凝聚态物质 · 物理学 2023-04-04 Shubhadeep Sadhukhan , Samo Penič , Aleš Iglič , Nir Gov

A continuum model of epithelial tissue mechanics was formulated using cellular-level mechanical ingredients and cell morphogenetic processes, including cellular shape changes and cellular rearrangements. This model can include finite…

组织与器官 · 定量生物学 2017-09-06 Shuji Ishihara , Philippe Marcq , Kaoru Sugimura

Cell migration is important in many biological processes, including embryonic development, cancer metastasis, and wound healing. In these tissues, a cell's motion is often strongly constrained by its neighbors, leading to glassy dynamics.…

生物物理 · 物理学 2016-01-20 Dapeng Bi , J. H. Lopez , J. M. Schwarz , M. Lisa Manning

The symmetry breaking of the actin network from radial to longitudinal symmetry has been identified as the major mechanism for keratocytes (fish cells) motility on solid substrate. For strong friction coefficient, the two dimensional actin…

软凝聚态物质 · 物理学 2011-02-16 M. Ben Amar , O. V. Manyuhina , G. Napoli

This study proposes and explores a linear hydrodynamic thermo-elasticity system within mixture models, comprising fluid and solid phases, with a focus on biological tissues, particularly tumor-related phenomena. Although tumor growth is not…

偏微分方程分析 · 数学 2025-02-11 Michael Eden , Meraj Alam , Prakash Kumar , G P Raja Sekhar

Migratory and tissue resident cells exhibit highly branched morphologies to perform their function and to adapt to the microenvironment. Immune cells, for example, display transient branched shapes while exploring the surrounding tissues.…

生物物理 · 物理学 2024-04-02 Jiayi Liu , Javier Boix-Campos , Jonathan E. Ron , Johan M. Kux , Nir S. Gov , Pablo J. Sáez

Cell-cell adhesion is one the most fundamental mechanisms regulating collective cell migration during tissue development, homeostasis and repair, allowing cell populations to self-organize and eventually form and maintain complex tissue…

细胞行为 · 定量生物学 2022-11-16 Carles Falcó , Ruth E. Baker , José A. Carrillo

Wood, due to its biological origin, has the capacity to interact with water. Sorption/desorption of moisture is accompanied with swelling/shrinkage and softening/hardening of its stiffness. The correct prediction of the behavior of wood…

Recent experimental investigations into Hydra regeneration revealed a remarkable phenomenon: the morphological transformation of a tissue fragment from the incipient spherical configuration to a tube-like structure - the hallmark of a…

生物物理 · 物理学 2024-05-07 Oded Agam , Erez Braun

We present a principled data-driven strategy for learning deterministic hydrodynamic models directly from stochastic non-equilibrium active particle trajectories. We apply our method to learning a hydrodynamic model for the propagating…

软凝聚态物质 · 物理学 2022-01-24 Suryanarayana Maddu , Quentin Vagne , Ivo F. Sbalzarini

Active systems, from bacterial suspensions to cellular monolayers, are continuously driven out of equilibrium by local injection of energy from their constituent elements and exhibit turbulent-like and chaotic patterns. Here we demonstrate…

软凝聚态物质 · 物理学 2016-02-04 Amin Doostmohammadi , Michael F. Adamer , Sumesh P. Thampi , Julia M. Yeomans

We study the kinematics and dynamics of a highly compliant membrane disk placed head-on in a uniform flow. With increasing flow velocity, the membrane deforms nonlinearly into increasingly parachute-like shapes. These aerodynamically…

流体动力学 · 物理学 2023-09-11 Varghese Mathai , Asimanshu Das , Dante L. Naylor , Kenneth S. Breuer

Turbulence is most commonly associated with high Reynolds number flow, however the framework of turbulent dynamics has been conceptually extended to many other fields, such as magnetohydrodynamic turbulence, elastic wave turbulence in…

软凝聚态物质 · 物理学 2026-03-05 Wilhelm Sunde Lie , Ingve Simonsen , Paul Gunnar Dommersnes

This paper deals with flow-induced shape transitions of elastic capsules. The state of the art concerning both theory and experiments is briefly reviewed starting with dynamically induced small deformation of initially spherical capsules…

软凝聚态物质 · 物理学 2011-04-25 Reimar Finken , Steffen Kessler , Udo Seifert

Chiral fluids - such as fluids under rotation or a magnetic field as well as synthetic and biological active fluids - flow in a different way than ordinary ones. Due to symmetries broken at the microscopic level, chiral fluids may have…

软凝聚态物质 · 物理学 2024-09-04 Tali Khain , Michel Fruchart , Colin Scheibner , Thomas A. Witten , Vincenzo Vitelli

The dynamics of cellular aggregates is driven by the interplay of mechanochemical processes and cellular activity. Although deterministic models may capture mechanical features, local chemical fluctuations trigger random cell responses,…

软凝聚态物质 · 物理学 2024-01-17 Ana Carpio , Elena Cebrian

Continuum hydrodynamic models of active liquid crystals have been used to describe dynamic self-organising systems such as bacterial swarms and cytoskeletal gels. A key prediction of such models is the existence of self-stabilising kink…

软凝聚态物质 · 物理学 2009-11-13 S. A. Edwards , J. M. Yeomans

The dynamics of a membrane coupled to an active fluid on top of a substrate is considered theoretically. It is assumed that the director field of the active fluid has rotational symmetry in the membrane plane. This situation is likely to be…

软凝聚态物质 · 物理学 2020-04-08 Chia-Chun Liang , Kento Yasuda , Shigeyuki Komura , Kuo-An Wu , Hsuan-Yi Chen

Plastic rearrangements play a crucial role in the characterization of soft-glassy materials, such as emulsions and foams. Based on numerical simulations of soft-glassy systems, we study the dynamics of plastic rearrangements at the…

软凝聚态物质 · 物理学 2014-10-27 R. Benzi , M. Sbragaglia , A. Scagliarini , P. Perlekar , M. Bernaschi , S. Succi , F. Toschi