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We describe a new method for evaluating Bayes factors. The key idea is to introduce a hypermodel in which the competing models are components of a mixture distribution. Inference for the mixing probabilities then yields estimates of the…

统计方法学 · 统计学 2016-02-16 Philip D. O'Neill , Theodore Kypraios

The vast majority of models for the spread of communicable diseases are parametric in nature and involve underlying assumptions about how the disease spreads through a population. In this article we consider the use of Bayesian…

统计方法学 · 统计学 2017-06-12 Theodore Kypraios , Philip D. O'Neill

Stochastic kinetic models are often used to describe complex biological processes. Typically these models are analytically intractable and have unknown parameters which need to be estimated from observed data. Ideally we would have…

统计计算 · 统计学 2018-03-13 Richard J. Boys , Holly F. Ainsworth , Colin S. Gillespie

Deterministic compartmental models are predominantly used in the modeling of infectious diseases, though stochastic models are considered more realistic, yet are complicated to estimate due to missing data. In this paper we present a novel…

统计计算 · 统计学 2022-06-22 Shuying Wang , Stephen G. Walker

In order to model an epidemic, different approaches can be adopted. Mainly, the deterministic approach and the stochastic one. Recently, a large amount of literature has been published using the two approaches. The aim of this paper is to…

种群与进化 · 定量生物学 2023-01-30 Mohamed Mehdaoui

The acute phase of the Covid-19 pandemic has made apparent the need for decision support based upon accurate epidemic modeling. This process is substantially hampered by under-reporting of cases and related data incompleteness issues. In…

应用统计 · 统计学 2026-03-10 Anastasios Apsemidis , Nikolaos Demiris

This paper focuses on the estimation of partially observed branching processes. First, the estimators from a frequentist perspective proposed in the literature are reviewed. The main objective of this paper is to present computational tools…

统计计算 · 统计学 2026-05-21 Miguel González , Inés M. del Puerto , Manuel Serrano-Pastor

Some scientific research questions ask to guide decisions and others do not. By their nature frequentist hypothesis-tests yield a dichotomous test decision as result, rendering them rather inappropriate for latter types of research…

统计方法学 · 统计学 2021-10-20 Patrick Schwaferts , Thomas Augustin

Mathematical models of epidemics often use compartmental models dividing the population into several compartments. Based on a microscopic setting describing the temporal evolution of the subpopulation sizes in the compartments by stochastic…

种群与进化 · 定量生物学 2025-03-11 Florent Ouabo Kamkumo , Ibrahim Mbouandi Njiasse , Ralf Wunderlich

Epidemic models are always simplifications of real world epidemics. Which real world features to include, and which simplifications to make, depend both on the disease of interest and on the purpose of the modelling. In the present paper we…

概率论 · 数学 2008-12-19 Tom Britton , David Lindenstrand

In this paper we first introduce the general stochastic epidemic model for the spread of infectious diseases. Then we give methods for inferring model parameters such as the basic reproduction number $R_0$ and vaccination coverage $v_c$…

统计方法学 · 统计学 2014-11-14 Tom Britton , Federica Giardina

The study of epidemic models plays an important role in mathematical epidemiology. There are many researches on epidemic models using ordinary differential equations, partial differential equations or stochastic differential equations. In…

概率论 · 数学 2023-03-10 Yuqi Li , Lihua Zhang

Epidemics are inherently stochastic, and stochastic models provide an appropriate way to describe and analyse such phenomena. Given temporal incidence data consisting of, for example, the number of new infections or removals in a given time…

统计方法学 · 统计学 2024-05-24 Sam A. Whitaker , Andrew Golightly , Colin S. Gillespie , Theodore Kypraios

Epidemics are often modelled using non-linear dynamical systems observed through partial and noisy data. In this paper, we consider stochastic extensions in order to capture unknown influences (changing behaviors, public interventions,…

应用统计 · 统计学 2012-11-06 Joseph Dureau , Konstantinos Kalogeropoulos , Marc Baguelin

Tracking the spread of infectious disease during a pandemic has posed a great challenge to the governments and health sectors on a global scale. To facilitate informed public health decision-making, the concerned parties usually rely on…

统计方法学 · 统计学 2023-06-05 Tejasv Bedi , Yanxun Xu , Qiwei Li

The paper presents an algorithm for syndromic surveillance of an epidemic outbreak formulated in the context of stochastic nonlinear filtering. The dynamics of the epidemic is modeled using a generalized compartmental epidemiological model…

定量方法 · 定量生物学 2011-10-24 Alex Skvortsov , Branko Ristic

The effect of public health interventions on an epidemic are often estimated by adding the intervention to epidemic models. During the Covid-19 epidemic, numerous papers used such methods for making scenario predictions. The majority of…

统计方法学 · 统计学 2024-10-16 Heejong Bong , Valérie Ventura , Larry Wasserman

Bayesian methods are useful for statistical inference. However, real-world problems can be challenging using Bayesian methods when the data analyst has only limited prior knowledge. In this paper we consider a class of problems, called…

统计方法学 · 统计学 2019-11-20 Yixuan Qiu , Lingsong Zhang , Chuanhai Liu

This article investigates stochastic epidemic models with partial information and addresses the estimation of current values of not directly observable states. The latter is also called nowcasting and related to the so-called "dark figure"…

种群与进化 · 定量生物学 2025-06-03 Florent Ouabo Kamkumo , Ibrahim Mbouandi Njiasse , Ralf Wunderlich

The problem of model selection in the context of a system of stochastic differential equations (SDEs) has not been touched upon in the literature. Indeed, properties of Bayes factors have not been studied even in single SDE based model…

统计理论 · 数学 2018-04-18 Trisha Maitra , Sourabh Bhattacharya
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