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A major challenge in neuroscience is posed by the need for relating the emerging dynamical features of brain activity with the underlying modular structure of neural connections, hierarchically organized throughout several scales. The…

神经元与认知 · 定量生物学 2016-06-03 Pablo Villegas , Jorge Hidalgo , Paolo Moretti , Miguel A. Muñoz

The characterisation of the brain as a "connectome", in which the connections are represented by correlational values across timeseries and as summary measures derived from graph theory analyses, has been very popular in the last years.…

机器学习 · 计算机科学 2020-03-13 Tiago Azevedo , Luca Passamonti , Pietro Liò , Nicola Toschi

In this study we adopt predictive modelling to identify simultaneously commonalities and differences in multi-modal brain networks acquired within subjects. Typically, predictive modelling of functional connectomes from structural…

神经元与认知 · 定量生物学 2019-11-06 Fani Deligianni , Jonathan D. Clayden , Guang-Zhong Yang

Gaining insights into the structural and functional mechanisms of the brain has been a longstanding focus in neuroscience research, particularly in the context of understanding and treating neuropsychiatric disorders such as Schizophrenia…

计算机视觉与模式识别 · 计算机科学 2026-01-27 Badhan Mazumder , Lei Wu , Vince D. Calhoun , Dong Hye Ye

Brain structural networks are often represented as discrete adjacency matrices with elements summarizing the connectivity between pairs of regions of interest (ROIs). These ROIs are typically determined a-priori using a brain atlas. The…

统计计算 · 统计学 2023-08-11 William Consagra , Martin Cole , Xing Qiu , Zhengwu Zhang

The human connectome has become the very frequent subject of study of brain-scientists, psychologists, and imaging experts in the last decade. With diffusion magnetic resonance imaging techniques, unified with advanced data processing…

神经元与认知 · 定量生物学 2019-07-24 Mate Fellner , Balint Varga , Vince Grolmusz

Our understanding of the structure of the brain and its relationships with human traits is largely determined by how we represent the structural connectome. Standard practice divides the brain into regions of interest (ROIs) and represents…

应用统计 · 统计学 2023-06-13 Rongjie Liu , Meng Li , David B. Dunson

Functional connectivity, as estimated using resting state fMRI, has shown potential in bridging the gap between pathophysiology and cognition. However, clinical use of functional connectivity biomarkers is impeded by unreliable estimates of…

The brain's intricate connectome, a blueprint for its function, presents immense complexity, yet it arises from a compact genetic code, hinting at underlying low-dimensional organizational principles. This work bridges connectomics and…

人工智能 · 计算机科学 2025-05-28 Yubin Li , Xingyu Liu , Guozhang Chen

It has become increasingly popular to study the brain as a network due to the realization that functionality cannot be explained exclusively by independent activation of specialized regions. Instead, across a large spectrum of behaviors,…

神经元与认知 · 定量生物学 2014-07-22 Petko Bogdanov , Nazli Dereli , Danielle S. Bassett , Scott T. Grafton , Ambuj K. Singh

Individual differences in human intelligence can be modeled and predicted from in vivo neurobiological connectivity. Many established modeling frameworks for predicting intelligence, however, discard higher-order information about…

Brain network analysis is a useful approach to studying human brain disorders because it can distinguish patients from healthy people by detecting abnormal connections. Due to the complementary information from multiple modal neuroimages,…

图像与视频处理 · 电气工程与系统科学 2023-08-22 Qiankun Zuo , Yanfei Zhu , Libin Lu , Zhi Yang , Yuhui Li , Ning Zhang

The relationship between brain structure and function has been probed using a variety of approaches, but how the underlying structural connectivity of the human brain drives behavior is far from understood. To investigate the effect of…

神经元与认知 · 定量生物学 2018-11-15 Kanika Bansal , John D. Medaglia , Danielle S. Bassett , Jean M. Vettel , Sarah F. Muldoon

A key question in modern neuroscience is how cognitive changes in a human brain can be quantified and captured by functional connectomes (FC) . A systematic approach to measure pairwise functional distance at different brain states is…

神经元与认知 · 定量生物学 2018-09-26 Enrico Amico , Alex Arenas , Joaquin Goni

Brain function emerges from coordinated activity across anatomically connected regions, where structural connectivity (SC) -- the network of white matter pathways - provides the physical substrate for functional connectivity (FC) -- the…

神经元与认知 · 定量生物学 2025-07-09 Sam Frank Kelemen , Joaquín Gõni , Sérgio Pequito , Arian Ashourvan

We propose the Financial Connectome, a new scientific discipline that models financial markets through the lens of brain functional architecture. Inspired by the foundational work of group independent component analysis (groupICA) in…

计算金融 · 定量金融 2026-03-24 Yuda Bi , Vince D Calhoun

Multi-site studies are becoming important to increase statistical power, enhance generalizability, and to improve the likelihood of pooling relevant subgroups together activities. Even with harmonized imaging sequences, site-dependent…

神经元与认知 · 定量生物学 2019-09-11 Sumra Bari , Enrico Amico , Nicole Vike , Thomas M. Talavage , Joaquín Goñi

One of the central objectives of contemporary neuroimaging research is to create predictive models that can disentangle the connection between patterns of functional connectivity across the entire brain and various behavioral traits.…

Substantial evidence indicates that major psychiatric disorders are associated with distributed neural dysconnectivity, leading to strong interest in using neuroimaging methods to accurately predict disorder status. In this work, we are…

机器学习 · 统计学 2014-03-26 Takanori Watanabe , Daniel Kessler , Clayton Scott , Michael Angstadt , Chandra Sripada

Cognition is supported by neurophysiological processes that occur both in local anatomical neighborhoods and in distributed large-scale circuits. Recent evidence from network control theory suggests that white matter pathways linking…

神经元与认知 · 定量生物学 2016-06-30 John D. Medaglia , Shi Gu , Fabio Pasqualetti , Rebecca L. Ashare , Caryn Lerman , Joseph Kable , Danielle S. Bassett