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This work considers a continuous framework to characterize the population-level variability of structural connectivity. Our framework assumes the observed white matter fiber tract endpoints are driven by a latent random function defined…

统计计算 · 统计学 2022-07-19 William Consagra , Martin Cole , Zhengwu Zhang

In recent years, new and important perspectives were introduced in the field of neuroimaging with the emergence of the connectionist approach. In this new context, it is important to know not only which brain areas are activated by a…

神经元与认知 · 定量生物学 2019-04-17 Jean Faber , Priscila C. Antoneli , Guillem Via , Noemi S. Araújo , Daniel J. L. L. Pinheiro , Esper Cavalheiro

Brain connectomics is a developing field in neurosciences which strives to understand cognitive processes and psychiatric diseases through the analysis of interactions between brain regions. However, in the high-dimensional, low-sample, and…

应用统计 · 统计学 2019-11-15 Claire Donnat , Leonardo Tozzi , Susan Holmes

Non-invasive measurements of the human brain using magnetic resonance imaging (MRI) have significantly improved our understanding the brain's network organization by enabling measurement of anatomical connections between brain regions…

应用统计 · 统计学 2025-12-10 Keshav Motwani , Ali Shojaie , Ariel Rokem , Eardi Lila

The brain's structural connectome supports signal propagation between neuronal elements, shaping diverse coactivation patterns that can be captured as functional connectivity. While the link between structure and function remains an ongoing…

神经元与认知 · 定量生物学 2022-07-11 Yaqian Yang , Zhiming Zheng , Longzhao Liu , Hongwei Zheng , Yi Zhen , Yi Zheng , Xin Wang , Shaoting Tang

We present a statistical framework that jointly models brain shape and functional connectivity, which are two complex aspects of the brain that have been classically studied independently. We adopt a Riemannian modeling approach to account…

统计方法学 · 统计学 2024-04-26 Eardi Lila , John A. D. Aston

There has been huge interest in studying human brain connectomes inferred from different imaging modalities and exploring their relationship with human traits, such as cognition. Brain connectomes are usually represented as networks, with…

机器学习 · 统计学 2021-09-14 Meimei Liu , Zhengwu Zhang , David B. Dunson

Mapping of human brain structural connectomes via diffusion MRI offers a unique opportunity to understand brain structural connectivity and relate it to various human traits, such as cognition. However, head displacement during image…

神经元与认知 · 定量生物学 2024-09-13 Yizi Zhang , Meimei Liu , Zhengwu Zhang , David Dunson

Modeling the behavior of coupled networks is challenging due to their intricate dynamics. For example in neuroscience, it is of critical importance to understand the relationship between the functional neural processes and anatomical…

机器学习 · 计算机科学 2021-04-20 Hongyuan You , Sikun Lin , Ambuj K. Singh

Early brain development is characterized by the formation of a highly organized structural connectome. The interconnected nature of this connectome underlies the brain's cognitive abilities and influences its response to diseases and…

神经元与认知 · 定量生物学 2023-08-24 Yihan Wu , Lana Vasung , Camilo Calixto , Ali Gholipour , Davood Karimi

Mapping the brain imaging data to networks, where each node represents a specific area of the brain, has enabled an objective graph-theoretic analysis of human connectome. However, the latent structure on higher-order connections remains…

神经元与认知 · 定量生物学 2019-04-09 Bosiljka Tadic , Miroslav Andjelkovic , Roderick Melnik

Synchronization of brain activity fluctuations is believed to represent communication between spatially distant neural processes. These inter-areal functional interactions develop in the background of a complex network of axonal connections…

神经元与认知 · 定量生物学 2016-11-10 Ariel Haimovici , Pablo Balenzuela , Enzo Tagliazucchi

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

In this article, we study association between the structural connectome and cognitive profiles using a multi-response nonparametric regression model.The cognitive profiles are measured in terms of seven age-adjusted cognitive test scores.…

统计方法学 · 统计学 2022-12-06 Arkaprava Roy

Human brain structural networks contain sets of centrally embedded hub regions that enable efficient information communication. However, it remains largely unknown about categories of structural brain hubs and their microstructural,…

神经元与认知 · 定量生物学 2016-09-13 Xindi Wang , Qixiang Lin , Mingrui Xia , Yong He

The study of functional brain connectivity (FC) is important for understanding the underlying mechanisms of many psychiatric disorders. Many recent analyses adopt graph convolutional networks, to study non-linear interactions between…

神经元与认知 · 定量生物学 2021-09-08 Simon Dahan , Logan Z. J. Williams , Daniel Rueckert , Emma C. Robinson

The human structural connectome has a complex internal community organization, characterized by a high degree of overlap and related to functional and cognitive phenomena. We explored connectivity properties in connectome networks and…

无序系统与神经网络 · 物理学 2025-02-24 V. Tiselko , O. Dogonasheva , A. Myshkin , O. Valba

Human brain connectome studies aim at extracting and analyzing relevant features associated to pathologies of interest. Usually this consists in modeling the brain connectome as a graph and in using graph metrics as features. A fine brain…

Recent advances in neuroimaging along with algorithmic innovations in statistical learning from network data offer a unique pathway to integrate brain structure and function, and thus facilitate revealing some of the brain's organizing…

信号处理 · 电气工程与系统科学 2021-12-21 Yang Li , Gonzalo Mateos , Zhengwu Zhang

Advances in data analysis and machine learning have revolutionized the study of brain signatures using fMRI, enabling non-invasive exploration of cognition and behavior through individual neural patterns. Functional connectivity (FC), which…

图像与视频处理 · 电气工程与系统科学 2025-10-31 Yashaswini , Sanjay Ghosh