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High failure rates in cardiac drug development necessitate virtual clinical trials via electrocardiogram (ECG) generation to reduce risks and costs. However, existing ECG generation models struggle to balance morphological realism with…

机器学习 · 计算机科学 2026-03-31 Qian Shao , Bang Du , Zepeng Li , Qiyuan Chen , Jiahe Chen , Hongxia Xu , Jimeng Sun , Jian Wu , Jintai Chen

We consider a problem of diagnostic pattern recognition/classification from neuroimaging data. We propose a common data analysis pipeline for neuroimaging-based diagnostic classification problems using various ML algorithms and processing…

Improving the future of healthcare starts by better understanding the current actual practices in hospital settings. This motivates the objective of discovering typical care pathways from patient data. Revealing typical care pathways can be…

机器学习 · 计算机科学 2024-12-20 Thomas Guyet , Pierre Pinson , Enoal Gesny

The progression of chronic diseases often follows highly variable trajectories, and the underlying factors remain poorly understood. Standard mixed-effects models typically represent inter-patient differences as random deviations around a…

This paper presents TimelinePTC, a web-based tool developed to improve the collection and analysis of Pathways to Care (PTC) data in first episode psychosis (FEP) research. Accurately measuring the duration of untreated psychosis (DUP) is…

人机交互 · 计算机科学 2024-04-22 Walter S. Mathis , Maria Ferrara , John Cahill , Sneha Karmani , Sümeyra N. Tayfur , Vinod Srihari

The wealth of computerised medical information becoming readily available presents the opportunity to examine patterns of illnesses, therapies and responses. These patterns may be able to predict illnesses that a patient is likely to…

机器学习 · 计算机科学 2013-07-05 Jenna Reps , Jonathan M. Garibaldi , Uwe Aickelin , Daniele Soria , Jack E. Gibson , Richard B. Hubbard

A meaningful understanding of clinical protocols and patient pathways helps improve healthcare outcomes. Electronic health records (EHR) reflect real-world treatment behaviours that are used to enhance healthcare management but present…

机器学习 · 计算机科学 2021-10-05 Adrian Caruana , Madhushi Bandara , Daniel Catchpoole , Paul J Kennedy

Discrete- and continuous-time approaches are frequently used to model the role of heterogeneity on dynamical interacting agents on the top of complex networks. While, on the one hand, one does not expect drastic differences between these…

物理与社会 · 物理学 2024-02-16 Diogo H. Silva , Francisco A. Rodrigues , Silvio C. Ferreira

Predicting the patient's clinical outcome from the historical electronic medical records (EMR) is a fundamental research problem in medical informatics. Most deep learning-based solutions for EMR analysis concentrate on learning the…

机器学习 · 计算机科学 2019-11-28 Liantao Ma , Chaohe Zhang , Yasha Wang , Wenjie Ruan , Jiantao Wang , Wen Tang , Xinyu Ma , Xin Gao , Junyi Gao

Electronic health records (EHR's) are only a first step in capturing and utilizing health-related data - the problem is turning that data into useful information. Models produced via data mining and predictive analysis profile inherited…

数据库 · 计算机科学 2011-12-08 Casey Bennett , Thomas Doub

Improving the precision of heart diseases detection has been investigated by many researchers in the literature. Such improvement induced by the overwhelming health care expenditures and erroneous diagnosis. As a result, various…

计算机与社会 · 计算机科学 2018-03-29 Israa Ahmed Zriqat , Ahmad Mousa Altamimi , Mohammad Azzeh

Analysis of longitudinal Electronic Health Record (EHR) data is an important goal for precision medicine. Difficulty in applying Machine Learning (ML) methods, either predictive or unsupervised, stems in part from the heterogeneity and…

Pragmatic trials increasingly define outcomes using real-world data such as electronic health records, where assessments are collected during routine care rather than at fixed timepoints. Consequently, these uncontrolled assessments may be…

The sequence of visits and procedures performed by the patient in the health system, also known as the patient's pathway or trajectory, can reveal important information about the clinical treatment adopted and the health service provided.…

Understanding the spread of any disease is a highly complex and interdisciplinary exercise as biological, social, geographic, economic, and medical factors may shape the way a disease moves through a population and options for its eventual…

种群与进化 · 定量生物学 2016-12-14 Aristides Moustakas

Increasingly, researchers have suggested the benefits of temporal analysis to improve our understanding of the learning process. Sequential pattern mining (SPM), as a pattern recognition technique, has the potential to reveal the temporal…

机器学习 · 计算机科学 2023-05-02 Yingbin Zhang , Luc Paquette

Traditional machine learning methods face two main challenges in dealing with healthcare predictive analytics tasks. First, the high-dimensional nature of healthcare data needs labor-intensive and time-consuming processes to select an…

机器学习 · 计算机科学 2022-09-16 Mohammad Amin Morid , Olivia R. Liu Sheng , Joseph Dunbar

Multiple adverse health conditions co-occurring in a patient are typically associated with poor prognosis and increased office or hospital visits. Developing methods to identify patterns of co-occurring conditions can assist in diagnosis.…

计算与语言 · 计算机科学 2017-11-30 Moumita Bhattacharya , Claudine Jurkovitz , Hagit Shatkay

In today's world, healthcare is the most important factor affecting human life. Due to heavy work load it is not possible for personal healthcare. The proposed system acts as a preventive measure for determining whether a person is fit or…

The goal of personalized decision making is to map a unit's characteristics to an action tailored to maximize the expected outcome for that unit. Obtaining high-quality mappings of this type is the goal of the dynamic regime literature. In…

机器学习 · 计算机科学 2018-10-01 Razieh Nabi , Phyllis Kanki , Ilya Shpitser