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Electronic Health Records (EHRs) aggregate diverse information at the patient level, holding a trajectory representative of the evolution of the patient health status throughout time. Although this information provides context and can be…

机器学习 · 计算机科学 2022-09-12 João Figueira Silva , Sérgio Matos

In heterogeneous disorders like Parkinson's disease (PD), differentiating the affected population into subgroups plays a key role in future research. Discovering subgroups can lead to improved treatments through more powerful enrichment of…

统计方法学 · 统计学 2023-08-08 Elliot Burghardt , Daniel Sewell , Joseph Cavanaugh

Recent years have seen an increased focus into the tasks of predicting hospital inpatient risk of deterioration and trajectory evolution due to the availability of electronic patient data. A common approach to these problems involves…

机器学习 · 计算机科学 2020-11-18 Henrique Aguiar , Mauro Santos , Peter Watkinson , Tingting Zhu

In this work we addressed the problem of capturing sequential information contained in longitudinal electronic health records (EHRs). Clinical notes, which is a particular type of EHR data, are a rich source of information and practitioners…

计算与语言 · 计算机科学 2020-10-27 Andrey Kormilitzin , Nemanja Vaci , Qiang Liu , Hao Ni , Goran Nenadic , Alejo Nevado-Holgado

Clinical event sequences consist of hundreds of clinical events that represent records of patient care in time. Developing accurate predictive models of such sequences is of a great importance for supporting a variety of models for…

机器学习 · 计算机科学 2023-08-23 Jeong Min Lee , Milos Hauskrecht

In medical practice, treatments are selected based on the expected causal effects on patient outcomes. Here, the gold standard for estimating causal effects are randomized controlled trials; however, such trials are costly and sometimes…

机器学习 · 统计学 2023-01-24 Dennis Frauen , Tobias Hatt , Valentyn Melnychuk , Stefan Feuerriegel

Causal analysis based on non-uniform embedding schemes is an important way to detect the underlying interactions between dynamic systems. However, there are still some obstacles to estimate high-dimensional conditional mutual information…

统计方法学 · 统计学 2020-02-19 Ziyu Jia , Youfang Lin , Zehui Jiao , Yan Ma , Jing Wang

Given data obtained under two sampling conditions, it is often of interest to identify variables that behave differently in one condition than in the other. We introduce a method for differential analysis of second-order behavior called…

统计方法学 · 统计学 2016-02-26 Kelly Bodwin , Kai Zhang , Andrew Nobel

Predicting future system behaviour from past observed behaviour (time series) is fundamental to science and engineering. In computational neuroscience, the prediction of future epileptic seizures from brain activity measurements, using EEG…

We investigate the use of transfer entropy (TE) as a proxy to detect the contact patterns of the population in epidemic processes. We first apply the measure to a classical age-stratified SIR model and observe that the recovered patterns…

物理与社会 · 物理学 2023-06-02 Tiago Martinelli , Alberto Aleta , Francisco A. Rodrigues , Yamir Moreno

As machine learning continues to gain momentum in the neuroscience community, we witness the emergence of novel applications such as diagnostics, characterization, and treatment outcome prediction for psychiatric and neurological disorders,…

Electrophysiological observation plays a major role in epilepsy evaluation. However, human interpretation of brain signals is subjective and prone to misdiagnosis. Automating this process, especially seizure detection relying on scalp-based…

机器学习 · 计算机科学 2018-07-06 David Ahmedt-Aristizabal , Clinton Fookes , Kien Nguyen , Sridha Sridharan

Large observational clinical datasets become increasingly available for mining associations between various disease traits and administered therapy. These datasets can be considered as representations of the landscape of all possible…

Epidemic analyses increasingly rely on heterogeneous datasets, many of which are sensitive and require strong privacy protection. Although differential privacy (DP) has become a standard in machine learning and data sharing, its adoption in…

This paper presents a reproducible and process-aware pipeline for predictive monitoring of clinical pathways. The approach integrates data lifting, temporal reconstruction, event log construction, prefix-based representations, and…

机器学习 · 计算机科学 2026-05-13 Pasquale Ardimento , Mario Luca Bernardi , Marta Cimitile , Samuele Latorre

This paper presents a novel approach to simulating electronic health records (EHRs) using diffusion probabilistic models (DPMs). Specifically, we demonstrate the effectiveness of DPMs in synthesising longitudinal EHRs that capture…

机器学习 · 计算机科学 2023-03-23 Nicholas I-Hsien Kuo , Louisa Jorm , Sebastiano Barbieri

In recent years, applications of data mining methods are become more popular in many fields of medical diagnosis and evaluations. The data mining methods are appropriate tools for discovering and extracting of available knowledge in medical…

计算工程、金融与科学 · 计算机科学 2013-12-10 Peyman Mohammadi , Abdolreza Hatamlou , Mohammad Masdari

In recent years, healthcare professionals are increasingly emphasizing on personalized and evidence-based patient care through the exploration of prognostic pathways. To study this, structured clinical variables from Electronic Health…

计算与语言 · 计算机科学 2025-09-16 Sudeshna Jana , Tirthankar Dasgupta , Lipika Dey

Pandemic outbreaks such as COVID-19 occur unexpectedly, and need immediate action due to their potential devastating consequences on global health. Point-of-care routine assessments such as electrocardiogram (ECG), can be used to develop…

信号处理 · 电气工程与系统科学 2023-01-12 Weijie Sun , Sunil Vasu Kalmady , Nariman Sepehrvand , Luan Manh Chu , Zihan Wang , Amir Salimi , Abram Hindle , Russell Greiner , Padma Kaul

Estimating the Individual Treatment Effect from observational data, defined as the difference between outcomes with and without treatment or intervention, while observing just one of both, is a challenging problems in causal learning. In…

机器学习 · 计算机科学 2020-05-07 Céline Beji , Michaël Bon , Florian Yger , Jamal Atif