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Diffusion magnetic resonance imaging (dMRI) and tractography provide means to study the anatomical structures within the white matter of the brain. When studying tractography data across subjects, it is usually necessary to align, i.e. to…

机器学习 · 统计学 2016-02-01 Thien Bao Nguyen , Emanuele Olivetti , Paolo Avesani

Tractograms are virtual representations of the white matter fibers of the brain. They are of primary interest for tasks like presurgical planning, and investigation of neuroplasticity or brain disorders. Each tractogram is composed of…

神经元与认知 · 定量生物学 2020-07-10 Pietro Astolfi , Ruben Verhagen , Laurent Petit , Emanuele Olivetti , Jonathan Masci , Davide Boscaini , Paolo Avesani

White matter structures composed of myelinated axons in the living human brain are primarily studied by diffusion-weighted MRI (dMRI). These long-range projections are typically characterized in a two-step process: dMRI is used to estimate…

White matter tractography is an advanced neuroimaging technique that reconstructs the 3D white matter pathways of the brain from diffusion MRI data. It can be framed as a pathfinding problem aiming to infer neural fiber trajectories from…

计算机视觉与模式识别 · 计算机科学 2025-09-23 Itzik Waizman , Yakov Gusakov , Itay Benou , Tammy Riklin Raviv

While the major white matter tracts are of great interest to numerous studies in neuroscience and medicine, their manual dissection in larger cohorts from diffusion MRI tractograms is time-consuming, requires expert knowledge and is hard to…

计算机视觉与模式识别 · 计算机科学 2018-06-15 Jakob Wasserthal , Peter F. Neher , Klaus H. Maier-Hein

Diffusion MRI tractography technique enables non-invasive visualization of the white matter pathways in the brain. It plays a crucial role in neuroscience and clinical fields by facilitating the study of brain connectivity and neurological…

计算机视觉与模式识别 · 计算机科学 2025-03-06 Yiqiong Yang , Yitian Yuan , Baoxing Ren , Ye Wu , Yanqiu Feng , Xinyuan Zhang

Diffusion magnetic resonance imaging (dMRI) data allow to reconstruct the 3D pathways of axons within the white matter of the brain as a tractography. The analysis of tractographies has drawn attention from the machine learning and pattern…

机器学习 · 统计学 2015-04-03 Emanuele Olivetti , Thien Bao Nguyen , Paolo Avesani

One of the main issues of the current tractography methods is their high false-positive rate. Tractogram filtering is an option to remove false-positive streamlines from tractography data in a post-processing step. In this paper, we train a…

计算机视觉与模式识别 · 计算机科学 2023-07-13 Daniel Jörgens , Pierre-Marc Jodoin , Maxime Descoteaux , Rodrigo Moreno

In the present work, we use information theory to understand the empirical convergence rate of tractography, a widely-used approach to reconstruct anatomical fiber pathways in the living brain. Based on diffusion MRI data, tractography is…

定量方法 · 定量生物学 2018-06-13 Daniel Moyer , Paul M. Thompson , Greg Ver Steeg

We propose a novel and efficient algorithm to model high-level topological structures of neuronal fibers. Tractography constructs complex neuronal fibers in three dimensions that exhibit the geometry of white matter pathways in the brain.…

计算机视觉与模式识别 · 计算机科学 2021-08-04 S. Shailja , Angela Zhang , B. S. Manjunath

The state-of-the-art method for automatically segmenting white matter bundles in diffusion-weighted MRI is tractography in conjunction with streamline cluster selection. This process involves long chains of processing steps which are not…

计算机视觉与模式识别 · 计算机科学 2017-03-08 Jakob Wasserthal , Peter F. Neher , Fabian Isensee , Klaus H. Maier-Hein

While the major white matter tracts are of great interest to numerous studies in neuroscience and medicine, their manual dissection in larger cohorts from diffusion MRI tractograms is time-consuming, requires expert knowledge and is hard to…

计算机视觉与模式识别 · 计算机科学 2019-09-26 Jakob Wasserthal , Peter Neher , Dusan Hirjak , Klaus H. Maier-Hein

Fiber tractography on diffusion imaging data offers rich potential for describing white matter pathways in the human brain, but characterizing the spatial organization in these large and complex data sets remains a challenge. We show that…

统计方法学 · 统计学 2015-06-18 Brian P. Kent , Alessandro Rinaldo , Fang-Cheng Yeh , Timothy Verstynen

Tractography has become an indispensable part of brain connectivity studies. However, it is currently facing problems with reliability. In particular, a substantial amount of nerve fiber reconstructions (streamlines) in tractograms produced…

计算机视觉与模式识别 · 计算机科学 2023-07-25 Antonia Hain , Daniel Jörgens , Rodrigo Moreno

As tractography datasets continue to grow in size, there is a need for improved visualization methods that can capture structural patterns occurring in large tractography datasets. Transparency is an increasingly important aspect of finding…

图形学 · 计算机科学 2023-08-17 Besm Osman , Mestiez Pereira , Huub van de Wetering , Maxime Chamberland

Deep learning approaches for diffusion MRI have so far focused primarily on voxel-based segmentation of lesions or white-matter fiber tracts. A drawback of representing tracts as volumetric labels, rather than sets of streamlines, is that…

图像与视频处理 · 电气工程与系统科学 2020-09-10 Christian Ewert , David Kügler , Anastasia Yendiki , Martin Reuter

White matter bundle segmentation is crucial for studying brain structural connectivity, neurosurgical planning, and neurological disorders. White Matter Segmentation remains challenging due to structural similarity in streamlines, subject…

计算机视觉与模式识别 · 计算机科学 2025-02-24 Anoushkrit Goel , Simroop Singh , Ankita Joshi , Ranjeet Ranjan Jha , Chirag Ahuja , Aditya Nigam , Arnav Bhavsar

Diffusion MRI tractography enables in vivo reconstruction of white matter (WM) pathways. Two key tasks in tractography analysis include: 1) tractogram registration that aligns streamlines across individuals, and 2) streamline clustering…

计算机视觉与模式识别 · 计算机科学 2026-03-12 Yijie Li , Xi Zhu , Junyi Wang , Ye Wu , Lauren J. O'Donnell , Fan Zhang

Tractography algorithms are used extensively to delineate white matter structures, by operating on the voxel-wise information generated through the application of diffusion tensor imaging (DTI) or other models to diffusion weighted (DW)…

定量方法 · 定量生物学 2024-03-05 Richard G. Carson , Alexander Leemans

Tractography traces the peak directions extracted from fiber orientation distribution (FOD) suffering from ambiguous spatial correspondences between diffusion directions and fiber geometry, which is prone to producing erroneous tracks while…

计算机视觉与模式识别 · 计算机科学 2024-08-20 Yuanjing Feng , Lei Xie , Jingqiang Wang , Qiyuan Tian , Jianzhong He , Qingrun Zeng , Fei Gao
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