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This perspective will overview an emerging paradigm for self-organized soft materials, {\it geometrically-frustrated assemblies}, where interactions between self-assembling elements (e.g. particles, macromolecules, proteins) favor local…

软凝聚态物质 · 物理学 2016-09-20 Gregory M. Grason

The self-assembly of particles into organized structures is a key feature of living organisms and a major engineering challenge. While it may proceed through the binding of perfectly matched, puzzle-pieces-like particles, many other…

软凝聚态物质 · 物理学 2024-04-08 Hugo Le Roy , M. Mert Terzi , Martin lenz

Geometric frustration offers a pathway to soft matter self-assembly with controllable finite sizes. While the understanding of frustration in soft matter assembly derives almost exclusively from continuum elastic descriptions, a current…

软凝聚态物质 · 物理学 2023-08-08 Douglas M. Hall , Mark J. Stevens , Gregory M. Grason

Geometric frustration arises whenever the constituents of a physical assembly locally favor an arrangement that cannot be realized globally. Recently, such frustrated assemblies were shown to exhibit filamentation, size limitation, large…

软凝聚态物质 · 物理学 2021-12-15 Snir Meiri , Efi Efrati

Proteins can combine into functional elements in living cells or self-assemble into unwanted structures in a number of diseases. The resulting aggregates often display filamentous morphologies across a large range of protein shapes and…

软凝聚态物质 · 物理学 2026-05-18 Elena N. Govorun , Martin Lenz

Polymer-grafted nanoparticles are versatile building blocks that self-assemble into a rich diversity of mesostructures. Coarse-grained molecular simulations have commonly accompanied experiments by resolving structure formation pathways and…

软凝聚态物质 · 物理学 2025-09-30 Federico Tomazic , Aswathy Muttathukattil , Afshin Nabiyan , Felix Schacher , Michael Engel

Geometric frustration is a fundamental concept in various areas of physics, and its role in self-assembly processes has recently been recognized as a source of intricate self-limited structures. Here we present an analytic theory of the…

软凝聚态物质 · 物理学 2025-01-30 Nan Cheng , Kai Sun , Xiaoming Mao

Molecules provide the ultimate language in terms of which physiology and pathology must be understood. Myriads of proteins participate in elaborate networks of interactions and perform chemical activities coordinating the life of cells. To…

生物大分子 · 定量生物学 2025-02-10 R. Gonzalo Parra , Elizabeth A. Komives , Peter G. Wolynes , Diego U. Ferreiro

In living cells, proteins self-assemble into large functional structures based on specific interactions between molecularly complex patches. Due to this complexity, protein self-assembly results from a competition between a large number of…

软凝聚态物质 · 物理学 2024-12-10 Lara Koehler , Pierre Ronceray , Martin Lenz

Self-organized complex structures in nature, e.g. viral capsids, hierarchical biopolymers, and bacterial flagella, offer efficiency, adaptability, robustness, and multi-functionality. Can we program the self-assembly of three-dimensional…

软凝聚态物质 · 物理学 2022-01-11 Francesco Serafin , Jun Lu , Nicholas Kotov , Kai Sun , Xiaoming Mao

Geometrically frustrated solids with non-Euclidean reference metric are ubiquitous in biology and are becoming increasingly relevant in technological applications. Often they acquire a targeted con- figuration of incompatibility through…

软凝聚态物质 · 物理学 2017-08-02 Giuseppe Zurlo , Lev Truskinovsky

Geometrically frustrated assemblies where building blocks misfit have been shown to generate intriguing phenomena from self-limited growth, fiber formation, to structural complexity. We introduce a graph theory formulation of geometrically…

软凝聚态物质 · 物理学 2024-07-26 José M. Ortiz-Tavárez , Zhen Yang , Nicholas Kotov , Xiaoming Mao

Understanding protein self-assembly is important for many biological and industrial processes. Proteins can self-assemble into crystals, filaments, gels, and other amorphous aggregates. The final forms include virus capsids and condensed…

软凝聚态物质 · 物理学 2016-04-15 Jennifer J. McManus , Patrick Charbonneau , Emanuela Zaccarelli , Neer Asherie

Assembling parts into an object is a combinatorial problem that arises in a variety of contexts in the real world and involves numerous applications in science and engineering. Previous related work tackles limited cases with identical unit…

计算机视觉与模式识别 · 计算机科学 2022-06-22 Jinhwi Lee , Jungtaek Kim , Hyunsoo Chung , Jaesik Park , Minsu Cho

The functionality of proteins is related to their structure in the native state. Protein structures are made up of emergent building blocks of helices and almost planar sheets. A simple coarse-grained geometrical model of a flexible tube…

Geometrical frustration in thin sheets is ubiquitous across scales in biology and becomes increasingly relevant in technology. Previous research identified the origin of the frustration as the violation of Gauss's \emph{Theorema Egregium}.…

软凝聚态物质 · 物理学 2021-02-16 Emmanuel Siéfert , Ido Levin , Eran Sharon

Geometric frustration appears in a broad range of systems, generally emerging as disordered ground configurations, thereby impeding understanding of the phenomenon's underlying mechanics. We report on a continuum system featuring locally…

应用物理 · 物理学 2021-06-04 Janav P. Udani , Andres F. Arrieta

Chirality frustrates and shapes the assembly of flexible filaments in rope-like, twisted bundles and fibers by introducing gradients of both filament shape (i.e. curvature) and packing throughout the structure. Previous models of chiral…

软凝聚态物质 · 物理学 2016-12-08 Douglas M. Hall , Gregory M. Grason

The protein folding problem must ultimately be solved on all length scales from the atomic up through a hierarchy of complicated structures. By analyzing the stability of the folding process using physics and mathematics, this paper shows…

生物物理 · 物理学 2015-05-28 Walter Simmons , Joel L. Weiner

We use computer simulations and simple theoretical models to analyze the morphologies that result when rod-like particles end-attach onto a curved surface, creating a finite-thickness monolayer aligned with the surface normal. This geometry…

软凝聚态物质 · 物理学 2016-07-01 Naiyin Yu , Abhijit Ghosh , Michael F. Hagan
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