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Electronic Health Record (EHR) systems provide critical, rich and valuable information at high frequency. One of the most exciting applications of EHR data is in developing a real-time mortality warning system with tools from survival…

机器学习 · 计算机科学 2021-11-12 Zhale Nowroozilarki , Arash Pakbin , James Royalty , Donald K. K. Lee , Bobak J. Mortazavi

The ability to perform accurate prognosis of patients is crucial for proactive clinical decision making, informed resource management and personalised care. Existing outcome prediction models suffer from a low recall of infrequent positive…

Antimicrobial Resistance represents a significant challenge in the Intensive Care Unit (ICU), where patients are at heightened risk of Multidrug-Resistant (MDR) infections-pathogens resistant to multiple antimicrobial agents. This study…

Prognosis on the occurrence of relapses in individuals with Relapsing-Remitting Multiple Sclerosis (RRMS), the most common subtype of Multiple Sclerosis (MS), could support individualized decisions and disease management and could be…

In healthcare, patient risk stratification models are often learned using time-series data extracted from electronic health records. When extracting data for a clinical prediction task, several formulations exist, depending on how one…

机器学习 · 计算机科学 2018-12-03 Eli Sherman , Hitinder Gurm , Ulysses Balis , Scott Owens , Jenna Wiens

We present a scalable end-to-end classifier that uses streaming physiological and medication data to accurately predict the onset of sepsis, a life-threatening complication from infections that has high mortality and morbidity. Our proposed…

机器学习 · 统计学 2017-06-14 Joseph Futoma , Sanjay Hariharan , Katherine Heller

In this paper, we are presenting a novel method and system for neuropsychological performance testing that can establish a link between cognition and emotion. It comprises a portable device used to interact with a cloud service which stores…

神经与进化计算 · 计算机科学 2022-12-13 Frederic Jumelle , Kelvin So , Didan Deng

Background: Subgroup analyses are frequently conducted in randomized clinical trials to assess evidence of heterogeneous treatment effect across patient subpopulations. Although randomization balances covariates within subgroups in…

统计方法学 · 统计学 2021-05-27 Siyun Yang , Fan Li , Laine E. Thomas , Fan Li

Leveraging external or historical data to improve the efficiency of randomized clinical trials without introducing bias or inflating the Type I error rate remains challenging. Recent work on externally trained prognostic scores, such as…

统计方法学 · 统计学 2026-05-28 Junyi Zhou , Qing Liu , May Mo , Amy Xia

Purpose: Health recommenders act as important decision support systems, aiding patients and medical professionals in taking actions that lead to patients' well-being. These systems extract the information which may be of particular…

机器学习 · 计算机科学 2024-07-02 Abhishek Dey , Debayan Goswami , Rahul Roy , Susmita Ghosh , Yu Shrike Zhang , Jonathan H. Chan

Hospitals lack automated systems to harness the growing volume of heterogeneous clinical and operational data to effectively forecast critical events. Early identification of patients at risk for deterioration is essential not only for…

The identification of biomarkers with high predictive accuracy is a crucial task in medical research, as it can aid clinicians in making early decisions, thereby reducing morbidity and mortality in high-risk populations. Time-dependent…

统计方法学 · 统计学 2025-10-22 María Xosé Rodríguez-Álvarez , Vanda Inácio

Heart attack remain one of the greatest contributors to mortality in the United States and globally. Patients admitted to the intensive care unit (ICU) with diagnosed heart attack (myocardial infarction or MI) are at higher risk of death.…

机器学习 · 计算机科学 2023-05-11 Munib Mesinovic , Peter Watkinson , Tingting Zhu

Cardiovascular disease (CVDs) is a rapidly rising global concern due to unhealthy diets, lack of physical activity, and other factors. According to the World Health Organization (WHO), primary risk factors include elevated blood pressure,…

人工智能 · 计算机科学 2024-09-25 Shashi Shekhar Kumar , Anurag Harsh , Ritesh Chandra , Sonali Agarwal

Objective: realtime monitoring of invasive ventilation (iV) in intensive care units (ICUs) plays a crucial role in ensuring prompt interventions and better patient outcomes. However, conventional methods often overlook valuable insights…

计算与语言 · 计算机科学 2024-10-08 Arash Pakbin , Aaron Su , Donald K. K. Lee , Bobak J. Mortazavi

Early prediction of patients at risk of clinical deterioration can help physicians intervene and alter their clinical course towards better outcomes. In addition to the accuracy requirement, early warning systems must make the predictions…

机器学习 · 计算机科学 2021-02-16 Ibrahim Hammoud , Prateek Prasanna , IV Ramakrishnan , Adam Singer , Mark Henry , Henry Thode

The pressure of ever-increasing patient demand and budget restrictions make hospital bed management a daily challenge for clinical staff. Most critical is the efficient allocation of resource-heavy Intensive Care Unit (ICU) beds to the…

机器学习 · 计算机科学 2021-02-25 Emma Rocheteau , Pietro Liò , Stephanie Hyland

Paralytic Ileus (PI) patients are at high risk of death when admitted to the Intensive care unit (ICU), with mortality as high as 40\%. There is minimal research concerning PI patient mortality prediction. There is a need for more accurate…

机器学习 · 计算机科学 2021-08-04 Maryam Pishgar , Martha Razo , Julian Theis , Houshang Darabi

Within the intensive care unit (ICU), a wealth of patient data, including clinical measurements and clinical notes, is readily available. This data is a valuable resource for comprehending patient health and informing medical decisions, but…

机器学习 · 计算机科学 2023-12-13 Ryan King , Tianbao Yang , Bobak Mortazavi

Currently, many critical care indices are repetitively assessed and recorded by overburdened nurses, e.g. physical function or facial pain expressions of nonverbal patients. In addition, many essential information on patients and their…