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Breast cancer screening policies attempt to achieve timely diagnosis by the regular screening of apparently healthy women. Various clinical decisions are needed to manage the screening process; those include: selecting the screening tests…

机器学习 · 计算机科学 2016-02-02 Ahmed M. Alaa , Kyeong H. Moon , William Hsu , Mihaela van der Schaar

Background and Objective. With minor differences, most national colorectal cancer (CRC) screening programs in Europe consist of one-size-fits-all aged-based strategies. This paper provides a decision analysis-based approach to personalized…

应用统计 · 统计学 2025-03-07 Daniel Corrales , David Ríos Insua , Marino J. González

Patient triage plays a crucial role in healthcare, ensuring timely and appropriate care based on the urgency of patient conditions. Traditional triage methods heavily rely on human judgment, which can be subjective and prone to errors.…

机器学习 · 计算机科学 2023-10-11 Pietro Hiram Guzzi , Annamaria De Filippo , Pierangelo Veltri

The development of molecular diagnostic tools to achieve individualized medicine requires identifying predictive biomarkers associated with subgroups of individuals who might receive beneficial or harmful effects from different available…

统计方法学 · 统计学 2020-01-20 Shonosuke Sugasawa , Hisashi Noma

Many diseases display heterogeneity in clinical features and their progression, indicative of the existence of disease subtypes. Extracting patterns of disease variable progression for subtypes has tremendous application in medicine, for…

定量方法 · 定量生物学 2020-08-04 Sanjukta Krishnagopal

Proactive monitoring of one's health could avoid serious diseases as well as better maintain the individual's well-being. In today's IoT world, there has been numerous wearable technological devices to monitor/measure different health…

计算机与社会 · 计算机科学 2016-12-05 Shubhi Asthana , Ray Strong , Aly Megahed

Background Clinical trials are essential to advancing cancer treatments, yet fewer than 10% of adults with cancer enroll in trials, and many studies fail to meet accrual targets. Artificial intelligence (AI) could improve identification of…

We introduce profile matching, a multivariate matching method for randomized experiments and observational studies that finds the largest possible unweighted samples across multiple treatment groups that are balanced relative to a covariate…

统计方法学 · 统计学 2022-07-07 Eric R. Cohn , Jose R. Zubizarreta

Prior to seeking professional medical care it is increasingly common for patients to use online resources such as automated symptom checkers. Many such systems attempt to provide a differential diagnosis based on the symptoms elucidated…

人工智能 · 计算机科学 2016-06-08 Katherine Middleton , Mobasher Butt , Nils Hammerla , Steven Hamblin , Karan Mehta , Ali Parsa

There are various algorithms and methodologies used for automated screening of cervical cancer by segmenting and classifying cervical cancer cells into different categories. This study presents a critical review of different research papers…

机器学习 · 计算机科学 2018-11-05 Yasha Singh , Dhruv Srivastava , P. S. Chandranand , Dr. Surinder Singh

Studies have shown that the traces people leave when browsing the internet may indicate the onset of diseases such as cancer. Here we show that the adaptive engines of advertising systems in conjunction with clinically verified…

计算机与社会 · 计算机科学 2018-08-09 Elad Yom-Tov

Motivation: Uncovering the genomic causes of cancer, known as cancer driver genes, is a fundamental task in biomedical research. Cancer driver genes drive the development and progression of cancer, thus identifying cancer driver genes and…

基因组学 · 定量生物学 2020-07-03 Vu Viet Hoang Pham , Lin Liu , Cameron Bracken , Gregory Goodall , Jiuyong Li , Thuc Duy Le

Over the last decades, many prognostic models based on artificial intelligence techniques have been used to provide detailed predictions in healthcare. Unfortunately, the real-world observational data used to train and validate these models…

机器学习 · 计算机科学 2023-11-21 Alice Bernasconi , Alessio Zanga , Peter J. F. Lucas , Marco Scutari , Fabio Stella

In many clinical trials, individuals in different subgroups have experience differential treatment effects. This leads to individualized differences in treatment benefit. In this article, we introduce the general concept of predictive…

统计方法学 · 统计学 2018-07-11 Debashis Ghosh , Youngjoo Cho

Conventional medical cancer screening methods are costly, labor-intensive, and extremely difficult to scale. Although AI can improve cancer detection, most systems rely on complex or specialized medical data, making them impractical for…

机器学习 · 计算机科学 2026-04-29 Petr Philonenko , Vladimir Kokh , Pavel Blinov

Early screening for cancer has proven to improve the survival rate and spare patients from intensive and costly treatments due to late diagnosis. Cancer screening in the healthy population involves an initial risk stratification step to…

This paper presents a framework for incentivising colorectal cancer (CRC) screening programs from the perspective of policymakers and under the assumption that the citizens participating in the program have misaligned objectives. To do so,…

应用统计 · 统计学 2025-09-08 Daniel Corrales , David Rios Insua

We suggest that deep learning can be used for pre-screening cancer by analyzing demographic and anthropometric information of patients, as well as biological markers obtained from routine blood samples and relative risks obtained from…

机器学习 · 统计学 2023-02-07 Rolando Gonzales Martinez , Daan-Max van Dongen

Modern bio-technologies have produced a vast amount of high-throughput data with the number of predictors far greater than the sample size. In order to identify more novel biomarkers and understand biological mechanisms, it is vital to…

机器学习 · 统计学 2018-05-18 Kevin He , Jian Kang , Hyokyoung Grace Hong , Ji Zhu , Yanming Li , Huazhen Lin , Han Xu , Yi Li

Background and Objective: Only about 14 % of eligible EU citizens finally participate in colorectal cancer (CRC) screening programs despite it being the third most common type of cancer worldwide. The development of CRC risk models can…

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