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Rare transitions between long-lived metastable states underlie a great variety of physical, chemical and biological processes. Our quantitative understanding of reactive mechanisms has been driven forward by the insights of transition state…

We consider the application of Kramers theory to the microscopic calculation of rates of conformational transitions of macromolecules. The main difficulty in such an approach is to locate the transition state in a huge configuration space.…

生物大分子 · 定量生物学 2008-09-02 Marcello Sega , Pietro Faccioli , Francesco Pederiva , Henri Orland

The dynamics of active particles is of interest at many levels and is the focus of theoretical and experimental research. There have been many attempts to describe the dynamics of particles affected by random active forces in terms of an…

统计力学 · 物理学 2020-01-08 Dan Wexler , Nir S. Gov , Kim Ø. Rasmussen , Golan Bel

Activation processes govern noise-induced switching between long-lived states. In an equilibrium double well, the thermally activated switching rate exhibits a prefactor with a nonmonotonic dependence on environmental coupling, a…

介观与纳米尺度物理 · 物理学 2026-04-22 Daniel K. J. Boneß , Gabriel Margiani , Wolfgang Belzig , Alexander Eichler , Oded Zilberberg

The time evolution of the thermally activated decay rates is considered. This evolution is of particular importance for the recent nanoscale experiments discussed in the literature, where the potential barrier is relatively low (or the…

统计力学 · 物理学 2021-04-21 Maria Chushnyakova , Igor Gontchar , Natalya Khmyrova

The reactive process of barrier escaping from the metastable potential well is studied together with the extension of Kramers' rate formula to the fractional case. Characteristic quantities are computed for an thimbleful of insight into the…

化学物理 · 物理学 2015-02-24 Chun-Yang Wang

We investigate the escape rate of an overdamped, self-propelled spherical Brownian particle on a surface from a metastable potential well. Within a modeling in terms of a 1D constant speed of the particle's active dynamics we consider the…

软凝聚态物质 · 物理学 2016-10-12 Alexander Geiseler , Peter Hänggi , Gerhard Schmid

Many processes in chemistry, physics, and biology involve rare events in which the system escapes from a metastable state by surmounting an activation barrier. Examples range from chemical reactions, protein folding, and nucleation events…

化学物理 · 物理学 2020-10-07 Niels Zijlstra , Daniel Nettels , Rohit Satija , Dmitrii E. Makarov , Benjamin Schuler

A one-dimensional run-and-tumble particle (RTP) switches randomly between a left and right moving state of constant speed $v$. This type of motion arises in a wide range of applications in cell biology, including the unbiased growth and…

统计力学 · 物理学 2021-02-23 Paul C Bressloff

We explore the dependence of the thermally activated barrier crossing rate on various model parameters for a dimer that undergoes a Brownian motion on a piecewise linear bistable potential employing the method of adiabatic elimination of…

统计力学 · 物理学 2014-07-15 Mesfin Asfaw

Kramers' theory frames chemical reaction rates in solution as reactants overcoming a barrier in the presence of friction and noise. For weak coupling to the solution, the reaction rate is limited by the rate at which the solution can…

统计力学 · 物理学 2015-12-09 Kirill A. Velizhanin , Subin Sahu , Chih-Chun Chien , Yonatan Dubi , Michael Zwolak

We consider the rate of transition for a particle between two metastable states coupled to a thermal environment for various magnitudes of the coupling strength, using the recently proposed infrequent metadynamics approach (Tiwary and…

软凝聚态物质 · 物理学 2016-05-04 Pratyush Tiwary , B. J. Berne

We analyze the behavior of a Brownian particle moving in a double-well potential. The escape probability of this particle over the potential barrier from a metastable state toward another state is known as the Kramers problem. In this work…

混沌动力学 · 物理学 2009-11-13 A. O. Bolivar

The magnetization reversal time of ferromagnetic nanoparticles is investigated in the very low damping regime. The energy-controlled diffusion equation rooted in a generalization of the Kramers escape rate theory for point Brownian…

统计力学 · 物理学 2014-04-07 William T. Coffey , Yuri P. Kalmykov , Serguey V. Titov

Energy dissipation rate is an important parameter for nearly every experiment on turbulent flow. Mathematically precise relationships between energy dissipation rate and other measurable statistics for the case of anisotropic turbulence are…

流体动力学 · 物理学 2008-02-28 Reginald J. Hill

We theoretically study the trapping time distribution and the efficiency of the excitation energy transport in dendritic systems. Trapping of excitations, created at the periphery of the dendrimer, on a trap located at its core, is used as…

材料科学 · 物理学 2007-05-23 Dirk-Jan Heijs , Victor A. Malyshev , Jasper Knoester

We perform free-fall experiments with a charge-neutral, optically levitated nanoparticle. This is achieved using an optical tweezer that can be rapidly toggled on and off and vertically displaced, enabling the particle to be released and…

The escape rate of a Brownian particle over a potential barrier is accurately described by the Kramers theory. A quantitative theory explicitly taking the activity of Brownian particles into account has been lacking due to the inherently…

软凝聚态物质 · 物理学 2017-02-01 A. Sharma , R. Wittmann , J. M. Brader

The length-scale dependence of the dynamic entropy is studied in a molecular dynamics simulation of a binary Lennard-Jones liquid above the mode-coupling critical temperature $T_c$. A number of methods exist for estimating the entropy of…

软凝聚态物质 · 物理学 2009-10-31 Paolo Allegrini , Jack F. Douglas , Sharon C. Glotzer

The process of activation out a one-dimensional potential is investigated systematically in zero and nonzero temperature conditions. The features of the potential are traced through statistical escape out of its wells whose depths are tuned…

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