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Inferring a binary connectivity graph from resting-state fMRI data for a single subject requires making several methodological choices and assumptions that can significantly affect the results. In this study, we investigate the robustness…

统计方法学 · 统计学 2025-03-20 Alice Chevaux , Ali Fahkar , Kévin Polisano , Irène Gannaz , Sophie Achard

Network control theory has recently emerged as a promising approach for understanding brain function and dynamics. By operationalizing notions of control theory for brain networks, it offers a fundamental explanation for how brain dynamics…

定量方法 · 定量生物学 2020-03-20 Shikuang Deng , Shi Gu

This paper studies the problem of selecting input nodes (leaders) to make networks strong structurally controllable despite misbehaving nodes and edges. We utilize a graph-based characterization of network strong structural controllability…

系统与控制 · 电气工程与系统科学 2023-03-07 Waseem Abbas

In recent years, network analyses have been used to evaluate brain reorganization following stroke. However, many studies have often focused on single topological scales, leading to an incomplete model of how focal brain lesions affect…

Functional Connectivity (FC) matrices measure the regional interactions in the brain and have been widely used in neurological brain disease classification. However, a FC matrix is neither a natural image which contains shape and texture…

医学物理 · 物理学 2020-01-10 Xiaodan Xing , Qingfeng Li , Hao Wei , Minqing Zhang , Yiqiang Zhan , Xiang Sean Zhou , Zhong Xue , Feng Shi

A key question in modern neuroscience is how cognitive changes in a human brain can be quantified and captured by functional connectomes (FC) . A systematic approach to measure pairwise functional distance at different brain states is…

神经元与认知 · 定量生物学 2018-09-26 Enrico Amico , Alex Arenas , Joaquin Goni

Emerging brain network studies suggest that interactions between various distributed neuronal populations may be characterized by an organized complex topological structure. Many brain diseases are associated with altered topological…

神经元与认知 · 定量生物学 2016-03-24 Shuo Chen , F. DuBois Bowman , Yishi Xing

The distributed nature of the neural substrate, and the difficulty of establishing necessity from correlative data, combine to render the mapping of brain function a far harder task than it seems. Methods capable of combining connective…

We investigate the influence of indirect connections, interregional distance and collective effects on the large-scale functional networks of the human cortex. We study topologies of empirically derived resting state networks (RSNs),…

神经元与认知 · 定量生物学 2013-02-18 Vesna Vuksanović , Philipp Hövel

Functional connectivity (FC) is one of the most common inputs to fMRI-based predictive models, due to a combination of its simplicity and robustness. However, there may be a lack of theoretical models for the generation of FC. In this work,…

神经元与认知 · 定量生物学 2023-05-19 Anton Orlichenko , Gang Qu , Ziyu Zhou , Zhengming Ding , Yu-Ping Wang

Structural and functional neuroimaging modalities provide complementary windows into brain organization: structural imaging characterizes neural tissue anatomy and microstructure, while functional imaging captures dynamic patterns of neural…

统计方法学 · 统计学 2026-03-24 Sakul Mahat , Sharmistha Guha , Jessica Bernard

Brain networks from functional MRI have advanced our understanding of cortical activity and its disruption in neurodegenerative disorders. Recent work has increasingly focused on dynamic (time-varying) brain networks that capture both…

神经元与认知 · 定量生物学 2026-04-14 Nicolas Rubido , Venia Batziou , Marwan Fuad , Vesna Vuksanovic

Resting-state functional MRI (rs-fMRI) is widely used to noninvasively study human brain networks. Network functional connectivity is often estimated by calculating the timeseries correlation between blood-oxygen-level dependent (BOLD)…

定量方法 · 定量生物学 2017-01-25 Nan Xu , R. Nathan Spreng , Peter C. Doerschuk

Brain-computer interfaces (BCIs) enable users to interact with the external world using brain activity. Despite their potential in neuroscience and industry, BCI performance remains inconsistent in noninvasive applications, often…

神经元与认知 · 定量生物学 2024-07-17 Juliana Gonzalez-Astudillo , Fabrizio De Vico Fallani

We present a didactic introduction to spectral Dynamic Causal Modelling (DCM), a Bayesian state-space modelling approach used to infer effective connectivity from non-invasive neuroimaging data. Spectral DCM is currently the most widely…

神经元与认知 · 定量生物学 2023-09-07 Leonardo Novelli , Karl Friston , Adeel Razi

With recent advancements in non-invasive techniques for measuring brain activity, such as magnetic resonance imaging (MRI), the study of structural and functional brain networks through graph signal processing (GSP) has gained notable…

机器学习 · 计算机科学 2025-11-13 Martín Schmidt , Sara Silva , Federico Larroca , Gonzalo Mateos , Pablo Musé

Coronary heart disease (CHD) arises from complex interactions among uncontrollable factors, controllable lifestyle factors, and clinical indicators, where relationships are often uncertain. Fuzzy subgraph connectivity (FSC) provides a…

人工智能 · 计算机科学 2025-09-23 Shanookha Ali , Nitha Niralda P C

Brain connectomics is a developing field in neurosciences which strives to understand cognitive processes and psychiatric diseases through the analysis of interactions between brain regions. However, in the high-dimensional, low-sample, and…

应用统计 · 统计学 2019-11-15 Claire Donnat , Leonardo Tozzi , Susan Holmes

Multi-site studies are becoming important to increase statistical power, enhance generalizability, and to improve the likelihood of pooling relevant subgroups together activities. Even with harmonized imaging sequences, site-dependent…

神经元与认知 · 定量生物学 2019-09-11 Sumra Bari , Enrico Amico , Nicole Vike , Thomas M. Talavage , Joaquín Goñi

Diverse cognitive processes set different demands on locally segregated and globally integrated brain activity. However, it remains unclear how resting brains configure their functional organization to balance the demands on network…

神经元与认知 · 定量生物学 2022-04-25 Rong Wang , Mianxin Liu , Xinhong Cheng , Ying Wu , Andrea Hildebrandt , Changsong Zhou
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