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Subject motion in whole-body dynamic PET introduces inter-frame mismatch and seriously impacts parametric imaging. Traditional non-rigid registration methods are generally computationally intense and time-consuming. Deep learning approaches…

图像与视频处理 · 电气工程与系统科学 2022-06-29 Xueqi Guo , Bo Zhou , David Pigg , Bruce Spottiswoode , Michael E. Casey , Chi Liu , Nicha C. Dvornek

The aim of this paper is to discuss potential advances in PET kinetic models and direct reconstruction of kinetic parameters. As a prominent example we focus on a typical task in perfusion imaging and derive a system of…

最优化与控制 · 数学 2014-11-20 Louise Reips , Martin Burger , Ralf Engbers

This paper addresses the problem of recovering tracer kinetic parameters from multi-region measurement data in quantitative PET imaging using the reversible two tissue compartment model. Its main result is an extension of our previous work…

最优化与控制 · 数学 2025-04-15 Martin Holler , Erion Morina , Georg Schramm

Fourier ptychography microscopy(FP) is a recently developed computational imaging approach for microscopic super-resolution imaging. By turning on each light-emitting-diode (LED) located on different position on the LED array sequentially…

光学 · 物理学 2022-02-22 Delong Yang , Shaohui Zhang , Chuanjian Zheng , Guocheng Zhou , Lei Cao , Yao Hu , Qun Hao

Compartmental models based on tracer mass balance are extensively used in clinical and pre-clinical nuclear medicine in order to obtain quantitative information on tracer metabolism in the biological tissue. This paper is the first of a…

定量方法 · 定量生物学 2018-08-21 Fabrice Delbary , Sara Garbarino , Valentina Vivaldi

Positron emission tomography (PET) is widely used to assess metabolic activity, but its application is limited by the availability of radiotracers. 18F-labeled fluorodeoxyglucose (18F-FDG) is the most commonly used tracer but shows limited…

图像与视频处理 · 电气工程与系统科学 2025-06-24 Fang Chen , Weifeng Zhang , Xingyu Ai , BingXuan Li , An Li , Qiegen Liu

Several diseases of parkinsonian syndromes present similar symptoms at early stage and no objective widely used diagnostic methods have been approved until now. Positron emission tomography (PET) with $^{18}$F-FDG was shown to be able to…

The Task Group 211 report of the American Association of Physicists in Medicine (AAPM) reviewed static segmentation techniques in nuclear positronemission tomography (PET) imaging used in nuclear medicine. These methods, when applied to a…

医学物理 · 物理学 2023-06-29 Philippe Laporte , Claire Cohalan , Jean-François Carrier

Neurological Positron Emission Tomography (PET) is a critical imaging modality for diagnosing and studying neurodegenerative diseases like Alzheimer's disease. However, the inherent low spatial resolution of PET images poses significant…

医学物理 · 物理学 2025-02-24 Matthew Tivnan , Quanzheng Li

Sequential whole-body 18F-Fluorodeoxyglucose (FDG) positron emission tomography (PET) scans are regarded as the imaging modality of choice for the assessment of treatment response in the lymphomas because they detect treatment response when…

图像与视频处理 · 电气工程与系统科学 2021-06-10 Kai-Chieh Liang , Lei Bi , Ashnil Kumar , Michael Fulham , Jinman Kim

This paper develops a method of biologically guided deep learning for post-radiation FDG-PET image outcome prediction based on pre-radiation images and radiotherapy dose information. Based on the classic reaction-diffusion mechanism, a…

Standard Patlak plot is widely used to describe FDG kinetics for dynamic PET imaging. Whole-body Patlak parametric imaging remains constrained due to the need for a full-time input function. Here, we demonstrate the Relative Patlak (RP)…

Patlak model is widely used in 18F-FDG dynamic positron emission tomography (PET) imaging, where the estimated parametric images reveal important biochemical and physiology information. Because of better noise modeling and more information…

医学物理 · 物理学 2020-09-15 Nuobei Xie , Kuang Gong , Ning Guo , Zhixing Qin , Jianan Cui , Zhifang Wu , Huafeng Liu , Quanzheng Li

Recent studies suggest that combined analysis of Magnetic resonance imaging~(MRI) that measures brain atrophy and positron emission tomography~(PET) that quantifies hypo-metabolism provides improved accuracy in diagnosing Alzheimer's…

计算机视觉与模式识别 · 计算机科学 2018-07-31 Apoorva Sikka , Skand Vishwanath Peri , Deepti. R. Bathula

An image or volume of interest in positron emission tomography (PET) is reconstructed from pairs of gamma rays emitted from a radioactive substance. Many image reconstruction methods are based on estimation of pixels or voxels on some…

信号处理 · 电气工程与系统科学 2019-06-18 Azra Tafro , Damir Seršić , Ana Sović Kržić

We developed a positron emission tomography (PET) system for multiple-isotope imaging. Our PET system, named multiple-isotope PET (MI-PET), can distinguish between different tracer nuclides using coincidence measurement of prompt…

Combining dual-energy computed tomography (DECT) with positron emission tomography (PET) offers many potential clinical applications but typically requires expensive hardware upgrades or increases radiation doses on PET/CT scanners due to…

医学物理 · 物理学 2024-06-21 Siqi Li , Yansong Zhu , Benjamin A. Spencer , Guobao Wang

Our aim was to enhance visual quality and quantitative accuracy of dynamic positron emission tomography (PET)uptake images by improved image reconstruction, using sophisticated sparse penalty models that incorporate both 2D spatial+1D…

计算机视觉与模式识别 · 计算机科学 2019-06-17 Ida Häggström , Yizun Lin , Si Li , Andrzej Krol , Yuesheng Xu , C. Ross Schmidtlein

Dynamic positron emission tomography (PET) reconstruction often presents high noise due to the use of short duration frames to describe the kinetics of the radiotracer. Here we introduce a new method to calculate a kernel matrix to be used…

医学物理 · 物理学 2026-01-01 Alan Miranda , Steven Staelens

Fluorodeoxyglucose positron emission tomography (FDG-PET) imaging based 3D topographic brain glucose metabolism patterns from normal controls (NC) and individuals with dementia of Alzheimer's type (DAT) are used to train a novel multi-scale…