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Network-based analyses of high-throughput genomics data provide a holistic, systems-level understanding of various biological mechanisms for a common population. However, when estimating multiple networks across heterogeneous…

The emergence of novel pathogens and zoonotic diseases like the SARS-CoV-2 have underlined the need for developing novel diagnosis and intervention pipelines that can learn rapidly from small amounts of labeled data. Combined with…

Pathologists find tedious to examine the status of the sentinel lymph node on a large number of pathological scans. The examination process of such lymph node which encompasses metastasized cancer cells is histopathologically organized.…

计算机视觉与模式识别 · 计算机科学 2019-06-25 Amit Kumar Jaiswal , Ivan Panshin , Dimitrij Shulkin , Nagender Aneja , Samuel Abramov

Quantitatively predicting phenotype variables by the expression changes in a set of candidate genes is of great interest in molecular biology but it is also a challenging task for several reasons. First, the collected biological…

应用统计 · 统计学 2017-07-21 Emilie Devijver , Mélina Gallopin , Emeline Perthame

Prognostic task is of great importance as it closely related to the survival analysis of patients, the optimization of treatment plans and the allocation of resources. The existing prognostic models have shown promising results on specific…

图像与视频处理 · 电气工程与系统科学 2025-01-14 Binyu Zhang , Shichao Li , Junpeng Jian , Zhu Meng , Limei Guo , Zhicheng Zhao

Semi-supervised node classification on graph-structured data has many applications such as fraud detection, fake account and review detection, user's private attribute inference in social networks, and community detection. Various methods…

机器学习 · 计算机科学 2020-12-29 Binghui Wang , Jinyuan Jia , Neil Zhenqiang Gong

In this note, we examine the problem of identifying the interaction geometry among a known number of agents, adopting a consensus-type algorithm for their coordination. The proposed identification process is facilitated by introducing…

最优化与控制 · 数学 2015-03-19 Marzieh Nabi-Abdolyousefi , Mehran Mesbahi

Previously, image interpretation in radiology relied heavily on manual methods. However, manual classification of brain tumor medical images is time-consuming and labor-intensive. Even with shallow convolutional neural network models, the…

计算机视觉与模式识别 · 计算机科学 2025-12-04 Yufeng Li , Wenchao Zhao , Bo Dang , Weimin Wang

The task of data integration for multi-omics data has emerged as a powerful strategy to unravel the complex biological underpinnings of cancer. Recent advancements in graph neural networks (GNNs) offer an effective framework to model…

机器学习 · 计算机科学 2025-06-24 Payam Zohari , Mostafa Haghir Chehreghani

Graph neural networks (GNNs) achieve remarkable success in graph-based semi-supervised node classification, leveraging the information from neighboring nodes to improve the representation learning of target node. The success of GNNs at node…

机器学习 · 计算机科学 2020-07-28 Bingbing Xu , Junjie Huang , Liang Hou , Huawei Shen , Jinhua Gao , Xueqi Cheng

Repurposing existing drugs to treat new diseases is a cost-effective alternative to de novo drug development, but there are millions of potential drug-disease combinations to be considered with only a small fraction being viable. In silico…

定量方法 · 定量生物学 2025-10-24 Austin Polanco , M. E. J. Newman

Nucleus segmentation is a challenging task due to the crowded distribution and blurry boundaries of nuclei. Recent approaches represent nuclei by means of polygons to differentiate between touching and overlapping nuclei and have…

计算机视觉与模式识别 · 计算机科学 2023-03-17 Shengcong Chen , Changxing Ding , Minfeng Liu , Jun Cheng , Dacheng Tao

We used the Ladder Network [Rasmus et al. (2015)] to perform Hyperspectral Image Classification in a semi-supervised setting. The Ladder Network distinguishes itself from other semi-supervised methods by jointly optimizing a supervised and…

计算机视觉与模式识别 · 计算机科学 2018-12-05 Julian Büchel , Okan Ersoy

Network representation learning has aroused widespread interests in recent years. While most of the existing methods deal with edges as pairwise relationships, only a few studies have been proposed for hyper-networks to capture more…

社会与信息网络 · 计算机科学 2019-10-23 Jie Huang , Xin Liu , Yangqiu Song

In this paper the application of uncertainty modeling to convolutional neural networks is evaluated. A novel method for adjusting the network's predictions based on uncertainty information is introduced. This allows the network to be either…

计算机视觉与模式识别 · 计算机科学 2016-12-23 Rene Grzeszick , Sebastian Sudholt , Gernot A. Fink

Despite deep convolutional neural networks boost the performance of image classification and segmentation in digital pathology analysis, they are usually weak in interpretability for clinical applications or require heavy annotations to…

计算机视觉与模式识别 · 计算机科学 2020-02-10 Yongxiang Huang , Albert C. S. Chung

When multitudes of features can plausibly be associated with a response, both privacy considerations and model parsimony suggest grouping them to increase the predictive power of a regression model. Specifically, the identification of…

统计方法学 · 统计学 2024-05-07 Brandon Woosuk Park , Anand N. Vidyashankar , Tucker S. McElroy

Melanoma is the most malignant skin tumor and usually cancerates from normal moles, which is difficult to distinguish benign from malignant in the early stage. Therefore, many machine learning methods are trying to make auxiliary…

图像与视频处理 · 电气工程与系统科学 2022-04-22 Jiaqi Xue , Chentian Ma , Li Li , Xuan Wen

In this article, we propose a topological model to encode partial equivariance in neural networks. To this end, we introduce a class of operators, called P-GENEOs, that change data expressed by measurements, respecting the action of certain…

机器学习 · 统计学 2023-08-28 Lucia Ferrari , Patrizio Frosini , Nicola Quercioli , Francesca Tombari

In this paper, we propose an automatic brain tumor segmentation approach (e.g., PixelNet) using a pixel-level convolutional neural network (CNN). The model extracts feature from multiple convolutional layers and concatenate them to form a…

图像与视频处理 · 电气工程与系统科学 2022-04-26 Mobarakol Islam , Hongliang Ren