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This study addresses critical gaps in automated lymphoma segmentation from PET/CT images, focusing on issues often overlooked in existing literature. While deep learning has been applied for lymphoma lesion segmentation, few studies…

Partially-observed network data collected by link-tracing based sampling methods is often being studied to obtain the characteristics of a large complex network. However, little attention has been paid to sampling from directed networks…

社会与信息网络 · 计算机科学 2014-05-28 Mostafa Salehi , Hamid R. Rabiee

Precision medicine tailored to individual patients has gained significant attention in recent times. Machine learning techniques are now employed to process personalized data from various sources, including images, genetics, and…

机器学习 · 计算机科学 2023-11-27 Jie Lian , Xufang Luo , Caihua Shan , Dongqi Han , Varut Vardhanabhuti , Dongsheng Li

Network tomography is a crucial problem in network monitoring, where the observable path performance metric values are used to infer the unobserved ones, making it essential for tasks such as route selection, fault diagnosis, and traffic…

机器学习 · 计算机科学 2025-02-25 Yuntong Hu , Junxiang Wang , Liang Zhao

Networks are ubiquitous structure that describes complex relationships between different entities in the real world. As a critical component of prediction task over nodes in networks, learning the feature representation of nodes has become…

机器学习 · 计算机科学 2018-09-10 Hansheng Xue , Jiajie Peng , Xuequn Shang

This paper studies semi-supervised graph classification, which is an important problem with various applications in social network analysis and bioinformatics. This problem is typically solved by using graph neural networks (GNNs), which…

机器学习 · 计算机科学 2022-05-24 Wei Ju , Junwei Yang , Meng Qu , Weiping Song , Jianhao Shen , Ming Zhang

Heterogeneity is a fundamental characteristic of cancer. To accommodate heterogeneity, subgroup identification has been extensively studied and broadly categorized into unsupervised and supervised analysis. Compared to unsupervised…

统计方法学 · 统计学 2026-02-25 Xing Qin , Xu Liu , Shuangge Ma , Mengyun Wu

We present a physically-inspired model and an efficient algorithm to infer hierarchical rankings of nodes in directed networks. It assigns real-valued ranks to nodes rather than simply ordinal ranks, and it formalizes the assumption that…

物理与社会 · 物理学 2018-06-14 Caterina De Bacco , Daniel B. Larremore , Cristopher Moore

Despite considerable progress in genome- and proteome-based high-throughput screening methods and in rational drug design, the increase in approved drugs in the past decade did not match the increase of drug development costs. Network…

分子网络 · 定量生物学 2013-05-14 Peter Csermely , Tamas Korcsmaros , Huba J. M. Kiss , Gabor London , Ruth Nussinov

We introduce a new threshold model of social networks, in which the nodes influenced by their neighbours can adopt one out of several alternatives. We characterize the graphs for which adoption of a product by the whole network is possible…

社会与信息网络 · 计算机科学 2015-03-19 Krzysztof R. Apt , Evangelos Markakis

We present a new inference method based on approximate Bayesian computation for estimating parameters governing an entire network based on link-traced samples of that network. To do this, we first take summary statistics from an observed…

统计计算 · 统计学 2017-01-17 Jack Davis , Steven K. Thompson

Tumour heterogeneity in breast cancer poses challenges in predicting outcome and response to therapy. Spatial transcriptomics technologies may address these challenges, as they provide a wealth of information about gene expression at the…

图像与视频处理 · 电气工程与系统科学 2023-09-19 Md Mamunur Rahaman , Ewan K. A. Millar , Erik Meijering

A key challenge in medical decision making is learning treatment policies for patients with limited observational data. This challenge is particularly evident in personalized healthcare decision-making, where models need to take into…

机器学习 · 计算机科学 2024-03-01 Vrishabh Patil , Kara Hoppe , Yonatan Mintz

Recent applications of deep convolutional neural networks in medical imaging raise concerns about their interpretability. While most explainable deep learning applications use post hoc methods (such as GradCAM) to generate feature…

计算机视觉与模式识别 · 计算机科学 2023-04-17 Yuanyuan Wei , Roger Tam , Xiaoying Tang

Bipartite networks manifest as a stream of edges that represent transactions, e.g., purchases by retail customers. Many machine learning applications employ neighborhood-based measures to characterize the similarity among the nodes, such as…

社会与信息网络 · 计算机科学 2018-05-09 Nesreen K. Ahmed , Nick Duffield , Liangzhen Xia

Tie strength prediction, sometimes named weight prediction, is vital in exploring the diversity of connectivity pattern emerged in networks. Due to the fundamental significance, it has drawn much attention in the field of network analysis…

社会与信息网络 · 计算机科学 2020-01-16 Zhen Liu , Hu li , Chao Wang

Early and accurate detection through Pap smear analysis is critical to improving patient outcomes and reducing mortality of Cervical cancer. State-of-the-art (SOTA) Convolutional Neural Networks (CNNs) require substantial computational…

组织与器官 · 定量生物学 2025-09-23 Saifuddin Sagor , Md Taimur Ahad , Faruk Ahmed , Rokonozzaman Ayon , Sanzida Parvin

Recently, there has been a resurgence of interest in rigorous algorithms for the inference of cancer progression from genomic data. The motivations are manifold: (i) growing NGS and single cell data from cancer patients, (ii) need for novel…

机器学习 · 计算机科学 2016-02-25 Daniele Ramazzotti

Cellular phenotypes are determined by the dynamical activity of networks of co-regulated genes. Elucidating such networks is crucial for the understanding of normal cell physiology as well as for the dissection of complex pathologic…

分子网络 · 定量生物学 2007-05-23 Kai Wang , Nilanjana Banerjee , Adam Margolin , Ilya Nemenman , Katia Basso , Riccardo Favera , Andrea Califano

Disease phenotyping algorithms process observational clinical data to identify patients with specific diseases. Supervised phenotyping methods require significant quantities of expert-labeled data, while unsupervised methods may learn…

机器学习 · 计算机科学 2019-03-27 Victor Rodriguez , Adler Perotte