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A complex system comprises multiple interacting entities whose interdependencies form a unified whole, exhibiting emergent behaviours not present in individual components. Examples include the human brain, living cells, soft matter, Earth's…

Nonparametric estimation of the mean and covariance functions is ubiquitous in functional data analysis and local linear smoothing techniques are most frequently used. Zhang and Wang (2016) explored different types of asymptotic properties…

统计理论 · 数学 2025-01-28 Shaojun Guo , Dong Li , Xinghao Qiao , Yizhu Wang

Complex systems are characterized by a huge number of degrees of freedom often interacting in a non-linear manner. In many cases macroscopic states, however, can be characterized by a small number of order parameters that obey stochastic…

数据分析、统计与概率 · 物理学 2012-02-20 David Kleinhans

Integrating high-dimensional biological data into data-driven mechanistic modeling requires rigorous practical identifiability to ensure interpretability and generalizability. However, coordinate identifiability analysis often suffers from…

定量方法 · 定量生物学 2026-02-25 Shun Wang , Wenrui Hao

Neural activity patterns related to behavior occur at many scales in time and space from the atomic and molecular to the whole brain. Here we explore the feasibility of interpreting neurophysiological data in the context of many-body…

其他定量生物学 · 定量生物学 2009-11-11 Walter J. Freeman , Giuseppe Vitiello

An Electroencephalogram (EEG) is a non-invasive exam that records the brain's electrical activity. This is used to help diagnose conditions such as different brain problems. EEG signals are taken for epilepsy detection, and with Discrete…

机器学习 · 计算机科学 2024-05-28 Rabel Guharoy , Nanda Dulal Jana , Suparna Biswas , Lalit Garg

The increasing frequency and severity of climate related disasters have intensified the need for real time monitoring, early warning, and informed decision-making. Earth Observation (EO), powered by satellite data and Machine Learning (ML),…

计算机视觉与模式识别 · 计算机科学 2026-05-12 Stella Girtsou , Konstantinos Alexis , Giorgos Giannopoulos , Charalambos Kontoes

Complex, oscillatory data arises from a large variety of biological, physical, and social systems. However, the inherent oscillation and ubiquitous noise pose great challenges to current methodology such as linear and nonlinear time series…

混沌动力学 · 物理学 2008-09-19 J. Zhang , K. Zhang , J. Feng , J. Sun , X. Xu , M. Small

The statistical problem of parameter estimation in partially observed hypoelliptic diffusion processes is naturally occurring in many applications. However, due to the noise structure, where the noise components of the different coordinates…

统计方法学 · 统计学 2018-11-13 Susanne Ditlevsen , Adeline Samson

Objective: A clinical decision support tool that automatically interprets EEGs can reduce time to diagnosis and enhance real-time applications such as ICU monitoring. Clinicians have indicated that a sensitivity of 95% with a specificity…

Biological oscillations are periodic changes in various signaling processes crucial for the proper functioning of living organisms. These oscillations are modeled by ordinary differential equations, with coefficient variations leading to…

机器学习 · 计算机科学 2024-12-04 Heng Rao , Yu Gu , Jason Zipeng Zhang , Ge Yu , Yang Cao , Minghan Chen

We develop here a stochastic framework for modeling and segmenting transient spindle-like oscillatory bursts in electroencephalogram (EEG) signals. At the modeling level, individual spindles are represented as path realizations of a…

神经元与认知 · 定量生物学 2025-12-13 C. Sun , D. Fettahoglu , D. Holcman

We consider statistical inference in factor analysis for ergodic and non-ergodic diffusion processes from discrete observations. Factor model based on high frequency time series data has been mainly discussed in the field of high…

统计理论 · 数学 2022-02-04 Shogo Kusano , Masayuki Uchida

In neuroscience, researchers typically conduct experiments under multiple conditions to acquire neural responses in the form of high-dimensional spike train datasets. Analysing high-dimensional spike data is a challenging statistical…

机器学习 · 计算机科学 2024-10-28 Yididiya Y. Nadew , Xuhui Fan , Christopher J. Quinn

Statistical inference on histograms and frequency counts plays a central role in categorical data analysis. Moving beyond classical methods that directly analyze labeled frequencies, we introduce a framework that models the multiset of…

统计理论 · 数学 2025-11-10 Yun Ma , Pengkun Yang

In this paper, we study inference for high-dimensional data characterized by small sample sizes relative to the dimension of the data. In particular, we provide an infinite-dimensional framework to study statistical models that involve…

统计理论 · 数学 2010-02-25 Jim Kuelbs , Anand N. Vidyashankar

The analysis of chaotic signals with time-frequency methods is considered. For this purpose, two new transformations are presented which consist in the decomposition of a signal onto an orthogonal set of respectively linear and hyperbolic…

混沌动力学 · 物理学 2010-07-28 Benjamin Ricaud , Francoise Briolle , F. Clairet

Mining time-frequency features is critical for time series forecasting. Existing research has predominantly focused on modeling low-frequency patterns, where most time series energy is concentrated. The overlooking of mid to high frequency…

机器学习 · 计算机科学 2026-03-11 Boya Zhang , Shuaijie Yin , Huiwen Zhu , Xing He

The method of instrumental variables provides a fundamental and practical tool for causal inference in many empirical studies where unmeasured confounding between the treatments and the outcome is present. Modern data such as the genetical…

统计方法学 · 统计学 2022-10-28 Ziang Niu , Yuwen Gu , Wei Li

In this paper, we evaluate various deep learning frameworks for detecting respiratory anomalies from input audio recordings. To this end, we firstly transform audio respiratory cycles collected from patients into spectrograms where both…

声音 · 计算机科学 2022-01-11 Lam Pham , Dat Ngo , Truong Hoang , Alexander Schindler , Ian McLoughlin