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Biofilms are ubiquitous macro-colonies of bacteria that develop at various interfaces (solid-liquid, solid-gas or liquid-gas). The formation of biofilms starts with the attachment of individual bacteria to an interface, where they…

生物物理 · 物理学 2016-11-03 Sarah Trinschek , Karin John , Uwe Thiele

Bacteria invade surfaces by forming dense colonies encased in a polymer matrix. Successful settlement of founder bacteria, early microcolony development and later macroscopic spreading of these biofilms on surfaces rely on complex physical…

软凝聚态物质 · 物理学 2025-08-27 Anthony Pietz , Karin John , Uwe Thiele

From multicellular tissues to bacterial colonies, three dimensional cellular structures arise through the interaction of cellular activities and mechanical forces. Simple bacterial communities provide model systems for analyzing such…

软凝聚态物质 · 物理学 2024-01-11 Ana Carpio , Elena Cebrian , David R. Espeso , Perfecto Vidal

Soft surfaces, spanning vastly different environmental and biomedical settings, are frequently colonised by surface-associated bacteria. Yet, how soft surfaces govern bacterial dynamics and their self-organisation into colonies remains…

生物物理 · 物理学 2025-12-29 Garima Rani , G. H. Philipp Nguyen , René Wittmann , Hartmut Löwen , Anupam Sengupta

The ability of bacteria to colonize and grow on different surfaces is an essential process for biofilm development and depends on complex biomechanical interactions between the biofilm and the underlying substrate. Changes in the physical…

生物物理 · 物理学 2021-03-16 Merrill Asp , Minh Tri Ho Thanh , Arvind Gopinath , Alison E. Patteson

Biofilms are bacterial aggregates that grow on moist surfaces. Thin homogeneous biofilms naturally formed on the walls of conducts may serve as biosensors, providing information on the status of microsystems (MEMS) without disrupting them.…

软凝聚态物质 · 物理学 2024-01-17 Ana Carpio , Baldvin Einarsson , David R. Espeso

The formation of bacterial biofilms on solid surfaces within a fluid starts when bacteria attach to the substrate. Understanding environmental factors affecting the attachment and the early stages of the biofilm development as well as the…

应用物理 · 物理学 2019-10-30 Sung-Ha Hong , Jean-Baptiste Gorce , Horst Punzmann , Nicolas Francois , Michael Shats , Hua Xia

Bacterial biofilms are usually assumed to originate from individual cells deposited on a surface. However, many biofilm-forming bacteria tend to aggregate in the planktonic phase so that it is possible that many natural and infectious…

We propose a computational framework to study the growth and spread of bacterial biofilms on interfaces, as well as the action of antibiotics on them. Bacterial membranes are represented by boundaries immersed in a fluid matrix and subject…

细胞行为 · 定量生物学 2022-01-11 Ana Carpio , Rafael Gonzalez-Albaladejo

Free boundaries of biofilms advancing on surfaces evolve according to conservation laws coupled with systems of partial differential equations for velocities, pressures and chemicals affecting cell behavior. Thin film approximations lead to…

偏微分方程分析 · 数学 2024-03-18 Ana Carpio , Gema Duro

In this paper we study kinetics of spreading of thin liquid films on solid interfaces. We present an overview of current experimental picture and discuss available theoretical approaches and their limitations. We report some new…

凝聚态物理 · 物理学 2007-05-23 S. F. Burlatsky , A. M. Cazabat , M. Moreau , G. Oshanin , S. Villette

Biofilms are bacterial aggregates encased in a self-produced polymeric matrix which attach to moist surfaces and are extremely resistant to chemicals and antibiotics. Recent experiments show that their structure is defined by the interplay…

软凝聚态物质 · 物理学 2024-01-17 Ana Carpio , Elena Cebrian , Perfecto Vidal

Biofilms are antibiotic-resistant bacterial aggregates that grow on moist surfaces and can trigger hospital-acquired infections. They provide a classical example in biology where the dynamics of cellular communities may be observed and…

生物物理 · 物理学 2015-02-24 D. R. Espeso , A. Carpio , B. Einarsson

Bacteria organize in a variety of collective states, from swarming, which has been attributed to rapid surface exploration, to biofilms, which are highly dense immobile communities attributed to stress resistance. It has been suggested that…

We present a study of the spreading of liquid droplets on a solid substrate at very small scales. We focus on the regime where effective wetting energy (binding potential) and surface tension effects significantly influence steady and…

流体动力学 · 物理学 2017-02-15 Hanyu Yin , David N. Sibley , Uwe Thiele , Andrew J. Archer

Formation of bacterial colonies as biofilm on the surface/interface of various objects has the potential to impact not only human health and disease but also energy and environmental considerations. Biofilms can be regarded as soft…

流体动力学 · 物理学 2015-09-15 Pallab Barai , Aloke Kumar , Partha P. Mukherjee

Two phase solid-fluid mixture models are ubiquitous in biological applications. For instance, models for growth of tissues and biofilms combine time dependent and quasi-stationary boundary value problems set in domains whose boundary moves…

偏微分方程分析 · 数学 2024-01-17 Ana Carpio , Gema Duro

The bacterium {\em Bacilus subtilis} frequently forms biofilms at the interface between the culture medium and the air. We develop a mathematical model that couples a description of bacteria as individual discrete objects to the standard…

细胞行为 · 定量生物学 2015-12-16 Maxime Ardré , Hervé Henry , Carine Douarche , Mathis Plapp

The spreading of bacterial colonies at solid-air interfaces is determined by the physico-chemical properties of the involved interfaces. The production of surfactant molecules by bacteria is a widespread strategy that allows the colony to…

生物物理 · 物理学 2018-07-24 Sarah Trinschek , Karin John , Uwe Thiele

Biofilms inhabit a range of environments, such as dental plaques or soil micropores, often characterized by intricate, non-even surfaces. However, the impact of surface irregularities on the population dynamics of biofilms remains elusive…

种群与进化 · 定量生物学 2023-08-31 Witold Postek , Klaudia Staskiewicz , Elin Lilja , Bartlomiej Waclaw
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