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Fast and sensitive detector arrays enable image scanning microscopy (ISM), overcoming the trade-off between spatial resolution and signal-to-noise ratio (SNR) typical of confocal microscopy. However, current ISM approaches cannot provide…

In this paper, we consider the MUltiple SIgnal Classification (MUSIC) algorithm for identifying the locations of small electromagnetic inhomogeneities surrounded by random scatterers. For this purpose, we rigorously analyze the structure of…

数值分析 · 数学 2016-02-05 Won-Kwang Park

Birdsong often contains large amounts of rapid frequency modulation (FM). It is believed that the use or otherwise of FM is adaptive to the acoustic environment, and also that there are specific social uses of FM such as trills in…

声音 · 计算机科学 2015-09-22 Dan Stowell , Mark D. Plumbley

We present an ultra-fast, precise, parameter-free method, which we term Deep-STORM, for obtaining super-resolution images from stochastically-blinking emitters, such as fluorescent molecules used for localization microscopy. Deep-STORM uses…

光学 · 物理学 2018-05-03 Elias Nehme , Lucien E. Weiss , Tomer Michaeli , Yoav Shechtman

Accurate biomedical image classification under low-resource conditions remains challenging due to limited annotations, subtle inter-class visual differences, and complex disease semantics. While vision--language models offer a promising…

计算机视觉与模式识别 · 计算机科学 2026-04-28 Xiaoliu Luo , Minxue Xiao , Ting Xie , Mengzhu Wang , Huiqing Qi , Joey Tianyi Zhou , Taiping Zhang , Xu Wang

High-speed multiplex imaging of fluorescent probes is limited by a combination of spectral resolution, sensitivity, high cost and low light throughput of detectors, and filters. In this work, we present a hyperspectral detection system…

Recently, super-resolution ultrasound imaging with ultrasound localization microscopy (ULM) has received much attention. However, ULM relies on low concentrations of microbubbles in the blood vessels, ultimately resulting in long…

Multimodal multilabel classification (MMC) is a challenging task that aims to design a learning algorithm to handle two data sources, the image and text, and learn a comprehensive semantic feature presentation across the modalities. In this…

计算机视觉与模式识别 · 计算机科学 2024-06-25 Yanming Guo

Single Molecule Localization Microscopy (SMLM) enables the acquisition of high-resolution images by alternating between activation of a sparse subset of fluorescent molecules present in a sample and localization. In this work, the…

图像与视频处理 · 电气工程与系统科学 2018-12-17 Arne Bechensteen , Laure Blanc-Féraud , Gilles Aubert

Super-resolution structured illumination microscopy (SR-SIM) is a widely used technique for enhancing the resolution of fluorescence imaging beyond the diffraction limit. Most existing SR-SIM methods rely on Moir\'e effect-based physical…

光学 · 物理学 2025-02-27 Junzheng Peng , Jiahao Xian , Xi Lin , Manhong Yao , Shiping Li , Jingang Zhong

Nonlinear structured illumination microscopy (nSIM) is an effective approach for super-resolution wide-field fluorescence microscopy with a theoretically unlimited resolution. In nSIM, carefully designed, highly-contrasted illumination…

Super-resolution is a fundamental task in imaging, where the goal is to extract fine-grained structure from coarse-grained measurements. Here we are interested in a popular mathematical abstraction of this problem that has been widely…

信息论 · 计算机科学 2015-04-30 Ankur Moitra

This paper concerns mathematical formulation of well-known MUltiple SIgnal Classification (MUSIC)-type imaging functional in the inverse scattering problem by an open sound-hard arc. Based on the physical factorization of so-called…

数值分析 · 数学 2018-01-09 Won-Kwang Park

Non-invasive detection of microvascular alterations in deep tissues in vivo provides critical information for clinical diagnosis and evaluation of a broad-spectrum of pathologies. Recently, the emergence of super-resolution ultrasound…

Multispectral imaging provides valuable information on tissue composition such as hemoglobin oxygen saturation. However, the real-time application of this technique in interventional medicine can be challenging due to the long acquisition…

Super-resolution imaging is vital for optical applications, such as high capacity information transmission, real-time bio-molecular imaging and nanolithography. Technology and method of super-resolution imaging have attracted much…

光学 · 物理学 2022-10-19 Yangyang Zhou , Huanyang Chen

Fluorescence microscopy is indispensable in nanoscience and biological sciences. The versatility of labeling target structures with fluorescent dyes permits to visualize structure and function at a subcellular resolution with a wide field…

Structured illumination microscopy (SIM) achieves superresolution in fluorescence imaging through patterned illumination and computational image reconstruction, yet current methods require bulky, costly modulation optics and high-precision…

光学 · 物理学 2024-04-15 Tamal Roy , Peter T. Brown , Douglas P. Shepherd , Lisa V. Poulikakos

Ultrafast ultrasound localization microscopy (ULM), which has shown promising results in microvascular imaging, overcomes the typical trade-off between resolution and penetration depth. Combining ultrasound contrast agents and high frame…

信号处理 · 电气工程与系统科学 2024-07-02 A. N. Madhavanunni , Niya Mariam Benoy , Mahesh Raveendranatha Panicker , Himanshu Shekhar

Automated interpretation of ultrasound imaging of the heart (echocardiograms) could improve the detection and treatment of aortic stenosis (AS), a deadly heart disease. However, existing deep learning pipelines for assessing AS from…

计算机视觉与模式识别 · 计算机科学 2024-03-12 Zhe Huang , Xiaowei Yu , Benjamin S. Wessler , Michael C. Hughes