相关论文: Transfer String Kernel for Cross-Context DNA-Prote…

In recent years, pre-trained large language models have achieved remarkable success across diverse tasks. Besides the pivotal role of self-supervised pre-training, their effectiveness in downstream applications also depends critically on…

Transcription factor proteins bind specific DNA sequences to control the expression of genes. They contain DNA binding domains which belong to several super-families, each with a specific mechanism of DNA binding. The total number of…

Double-strand DNA breaks (DSBs) are a form of DNA damage that can cause abnormal chromosomal rearrangements. Recent technologies based on high-throughput experiments have obvious high costs and technical challenges.Therefore, we design a…

Cellular nuclei recognition serves as a fundamental and essential step in the workflow of digital pathology. However, with disparate source organs and staining procedures among histology image clusters, the scanned tiles inherently conform…

Current transfer learning methods for high-dimensional linear regression assume feature alignment across domains, restricting their applicability to semantically matched features. In many real-world scenarios, however, distinct features in…

Transfer learning methods, and in particular domain adaptation, help exploit labeled data in one domain to improve the performance of a certain task in another domain. However, it is still not clear what factors affect the success of domain…

Search engines operate under a strict time constraint as a fast response is paramount to user satisfaction. Thus, neural re-ranking models have a limited time-budget to re-rank documents. Given the same amount of time, a faster re-ranking…

In this paper, we introduce a new idea for unsupervised domain adaptation via a remold of Prototypical Networks, which learn an embedding space and perform classification via a remold of the distances to the prototype of each class.…

This paper proposes a novel batch normalization strategy for test-time adaptation. Recent test-time adaptation methods heavily rely on the modified batch normalization, i.e., transductive batch normalization (TBN), which calculates the mean…

Graph neural networks (GNNs) have achieved superior performance on node classification tasks in the last few years. Commonly, this is framed in a transductive semi-supervised learning setup wherein the entire graph, including the target…

The popular methods for semi-supervised semantic segmentation mostly adopt a unitary network model using convolutional neural networks (CNNs) and enforce consistency of the model's predictions over perturbations applied to the inputs or…

Deep neural network (DNN) models have recently obtained state-of-the-art prediction accuracy for the transcription factor binding (TFBS) site classification task. However, it remains unclear how these approaches identify meaningful DNA…

Tensor Network (TN) Kernel Machines speed up model learning by representing parameters as low-rank TNs, reducing computation and memory use. However, most TN-based Kernel methods are deterministic and ignore parameter uncertainty. Further,…

Analysis of large-scale sequential data has been one of the most crucial tasks in areas such as bioinformatics, text, and audio mining. Existing string kernels, however, either (i) rely on local features of short substructures in the…

Hyperspectral image (HSI) classification presents inherent challenges due to high spectral dimensionality, significant domain shifts, and limited availability of labeled data. To address these issues, we propose a novel Active Transfer…

We study theoretical ``design principles'' for transcription factor-DNA interaction in bacteria, focusing particularly on the statistical interaction of the transcription factors (TF's) with the genomic background (i.e., the genome without…

Multivariate time series prediction has applications in a wide variety of domains and is considered to be a very challenging task, especially when the variables have correlations and exhibit complex temporal patterns, such as seasonality…

Clinical measurements collected over time are naturally represented as multivariate time series (MTS), which often contain missing data. An autoencoder can learn low dimensional vectorial representations of MTS that preserve important data…

To make DNA a suitable medium for archival data storage, it is essential to consider the decay process of the strands observed in DNA storage systems. This paper studies the decay process as a probabilistic noisy torn paper channel (TPC),…

The regulation of a gene depends on the binding of transcription factors to specific sites located in the regulatory region of the gene. The generation of these binding sites and of cooperativity between them are essential building blocks…