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The spatial location of cells within tissues and organs is crucial for the manifestation of their specific functions.Spatial transcriptomics technology enables comprehensive measurement of the gene expression patterns in tissues while…

定量方法 · 定量生物学 2024-07-12 Shuailin Xue , Fangfang Zhu , Changmiao Wang , Wenwen Min

In this paper, we propose a class of high-efficiency deep joint source-channel coding methods that can closely adapt to the source distribution under the nonlinear transform, it can be collected under the name nonlinear transform…

信息论 · 计算机科学 2022-11-03 Jincheng Dai , Sixian Wang , Kailin Tan , Zhongwei Si , Xiaoqi Qin , Kai Niu , Ping Zhang

Transfer learning for deep neural networks is the process of first training a base network on a source dataset, and then transferring the learned features (the network's weights) to a second network to be trained on a target dataset. This…

Treebank translation is a promising method for cross-lingual transfer of syntactic dependency knowledge. The basic idea is to map dependency arcs from a source treebank to its target translation according to word alignments. This method,…

计算与语言 · 计算机科学 2019-09-06 Zhang Meishan , Zhang Yue , Fu Guohong

Spatial transcriptomics (ST) has emerged as an advanced technology that provides spatial context to gene expression. Recently, deep learning-based methods have shown the capability to predict gene expression from WSI data using ST data.…

机器学习 · 计算机科学 2024-12-10 Mingcheng Qu , Yuncong Wu , Donglin Di , Anyang Su , Tonghua Su , Yang Song , Lei Fan

Accurate forecasting of recovery rates (RR) is central to credit risk management and regulatory capital determination. In many loan portfolios, however, RR modeling is constrained by data scarcity arising from infrequent default events.…

风险管理 · 定量金融 2026-04-24 Christopher Gerling , Hanqiu Peng , Ying Chen , Stefan Lessmann

Kernel methods are powerful tools in machine learning. They have to be computationally efficient. In this paper, we present a novel Geometric-based approach to compute efficiently the string subsequence kernel (SSK). Our main idea is that…

机器学习 · 计算机科学 2015-03-02 Slimane Bellaouar , Hadda Cherroun , Djelloul Ziadi

Deep text matching approaches have been widely studied for many applications including question answering and information retrieval systems. To deal with a domain that has insufficient labeled data, these approaches can be used in a…

信息检索 · 计算机科学 2019-01-01 Chen Qu , Feng Ji , Minghui Qiu , Liu Yang , Zhiyu Min , Haiqing Chen , Jun Huang , W. Bruce Croft

The identification of transcription factor binding sites (TFBSs) on genomic DNA is of crucial importance for understanding and predicting regulatory elements in gene networks. TFBS motifs are commonly described by Position Weight Matrices…

基因组学 · 定量生物学 2015-04-28 Marc Santolini , Thierry Mora , Vincent Hakim

Predicting clinical outcomes to anti-cancer drugs on a personalized basis is challenging in cancer treatment due to the heterogeneity of tumors. Traditional computational efforts have been made to model the effect of drug response on…

机器学习 · 计算机科学 2022-07-12 Jie Gao , Jing Hu , Wanqing Sun , Yili Shen , Xiaonan Zhang , Xiaomin Fang , Fan Wang , Guodong Zhao

Spatial transcriptomics is a technology that captures gene expression levels at different spatial locations, widely used in tumor microenvironment analysis and molecular profiling of histopathology, providing valuable insights into…

计算机视觉与模式识别 · 计算机科学 2025-06-11 Junzhuo Liu , Markus Eckstein , Zhixiang Wang , Friedrich Feuerhake , Dorit Merhof

Multivariate time series forecasting in graph-structured domains is critical for real-world applications, yet existing spatiotemporal models often suffer from performance degradation under data scarcity and cross-domain shifts. We address…

机器学习 · 计算机科学 2026-02-05 Zihao Jing , Yuxi Long , Ganlin Feng

Transfer learning is crucial in training deep neural networks on new target tasks. Current transfer learning methods always assume at least one of (i) source and target task label spaces overlap, (ii) source datasets are available, and…

机器学习 · 计算机科学 2025-02-21 Shin'ya Yamaguchi , Sekitoshi Kanai , Atsutoshi Kumagai , Daiki Chijiwa , Hisashi Kashima

We present a novel framework for kernel learning with sequential data of any kind, such as time series, sequences of graphs, or strings. Our approach is based on signature features which can be seen as an ordered variant of sample…

机器学习 · 统计学 2016-02-01 Franz J Király , Harald Oberhauser

As one of the fundamental tasks in computer vision, semantic segmentation plays an important role in real world applications. Although numerous deep learning models have made notable progress on several mainstream datasets with the rapid…

计算机视觉与模式识别 · 计算机科学 2020-10-06 Bin Zhang , Shengjie Zhao , Rongqing Zhang

We propose a novel text-to-speech (TTS) framework centered around a neural transducer. Our approach divides the whole TTS pipeline into semantic-level sequence-to-sequence (seq2seq) modeling and fine-grained acoustic modeling stages,…

音频与语音处理 · 电气工程与系统科学 2024-10-28 Minchan Kim , Myeonghun Jeong , Byoung Jin Choi , Semin Kim , Joun Yeop Lee , Nam Soo Kim

Spatial transcriptomics (ST) provides essential spatial context by mapping gene expression within tissue, enabling detailed study of cellular heterogeneity and tissue organization. However, aligning ST data with histology images poses…

Long-range contextual information is essential for achieving high-performance semantic segmentation. Previous feature re-weighting methods demonstrate that using global context for re-weighting feature channels can effectively improve the…

计算机视觉与模式识别 · 计算机科学 2020-08-27 Jianbo Liu , Junjun He , Jimmy S. Ren , Yu Qiao , Hongsheng Li

Post-translational modifications (PTMs) profoundly expand the complexity and functionality of the proteome, regulating protein attributes and interactions that are crucial for biological processes. Accurately predicting PTM sites and their…

机器学习 · 计算机科学 2024-11-05 Cheng Tan , Zhenxiao Cao , Zhangyang Gao , Lirong Wu , Siyuan Li , Yufei Huang , Jun Xia , Bozhen Hu , Stan Z. Li

Semantic segmentation of various tissue and nuclei types in histology images is fundamental to many downstream tasks in the area of computational pathology (CPath). In recent years, Deep Learning (DL) methods have been shown to perform well…

计算机视觉与模式识别 · 计算机科学 2023-02-14 Raja Muhammad Saad Bashir , Talha Qaiser , Shan E Ahmed Raza , Nasir M. Rajpoot