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Human learning is a complex process in which future behavior is altered via the reorganization of brain activity and connectivity. It remains unknown whether activity and connectivity differentially reorganize during learning, and, if so,…

Functional MRI (fMRI) and diffusion MRI (dMRI) are non-invasive imaging modalities that allow in-vivo analysis of a patient's brain network (known as a connectome). Use of these technologies has enabled faster and better diagnoses and…

机器学习 · 计算机科学 2016-12-06 Colin J Brown , Ghassan Hamarneh

Diffusion Tensor Imaging (DTI) is an effective tool for the analysis of structural brain connectivity in normal development and in a broad range of brain disorders. However efforts to derive inherent characteristics of structural brain…

计算工程、金融与科学 · 计算机科学 2018-02-14 Yu Jin , Joseph F. JaJa , Rong Chen , Edward H. Herskovits

The segregation of brain fiber tractography data into distinct and anatomically meaningful clusters can help to comprehend the complex brain structure and early investigation and management of various neural disorders. We propose a novel…

计算机视觉与模式识别 · 计算机科学 2017-10-17 Tushar Gupta , Shreyas Malakarjun Patil , Mukkaram Tailor , Daksh Thapar , Aditya Nigam

Neural network oscillations are a fundamental mechanism for cognition, perception and consciousness. Consequently, perturbations of network activity play an important role in the pathophysiology of brain disorders. When structural…

神经元与认知 · 定量生物学 2016-04-29 Timothée Proix , Fabrice Bartolomei , Maxime Guye , Viktor K. Jirsa

Functional connectivity (FC) refers to the investigation of interactions between brain regions to understand integration of neural activity in several regions. FC is often estimated using functional magnetic resonance images (fMRI). There…

应用统计 · 统计学 2023-01-24 Nathan Tung , Jerome Sanes , Eli Upfal , Ani Eloyan

One of the most well-established tools for modeling the brain as a complex system is the functional connectivity network, which examines the correlations between pairs of interacting brain regions. While powerful, the network model is…

信息论 · 计算机科学 2022-06-15 Thomas F. Varley , Maria Pope , Joshua Faskowitz , Olaf Sporns

This paper presents a spike-based model which employs neurons with functionally distinct dendritic compartments for classifying high dimensional binary patterns. The synaptic inputs arriving on each dendritic subunit are nonlinearly…

神经与进化计算 · 计算机科学 2014-11-26 Shaista Hussain , Shih-Chii Liu , Arindam Basu

Autism spectrum disorder (ASD) is a neurodevelopmental condition impacting high-level cognitive processing and social behavior. Recognizing the distributed nature of brain function, neuroscientists are exploiting the connectome to aid with…

神经元与认知 · 定量生物学 2019-09-26 Ai Wern Chung , Markus D. Schirmer

The human brain can be considered as complex networks, composed of various regions that continuously exchange their information with each other, forming the brain network graph, from which nodes and edges are extracted using resting-state…

机器学习 · 计算机科学 2025-02-19 Parnian Jalali , Mehran Safayani

This paper represents a contribution to the study of the brain functional connectivity from the perspective of complex networks theory. More specifically, we apply graph theoretical analyses to provide evidence of the modular structure of…

神经元与认知 · 定量生物学 2016-09-06 Giampiero Bardella , Angelo Bifone , Andrea Gabrielli , Alessandro Gozzi , Tiziano Squartini

We propose a framework for constructing combinatorial complexes (CCs) from fMRI time series data that captures both pairwise and higher-order neural interactions through information-theoretic measures, bridging topological deep learning and…

神经元与认知 · 定量生物学 2026-01-06 Valentina Sánchez , Çiçek Güven , Koen Haak , Theodore Papamarkou , Gonzalo Nápoles , Marie Šafář Postma

Brain activity is intrinsically a neural dynamic process constrained by anatomical space. This leads to significant variations in spatial distribution patterns and correlation patterns of neural activity across variable and heterogeneous…

机器学习 · 计算机科学 2026-03-10 Hongjie Jiang , Yifei Tang , Shuqiang Wang

The 3-hinge gyrus (3HG) is a newly defined folding pattern, which is the conjunction of gyri coming from three directions in cortical folding. Many studies demonstrated that 3HGs can be reliable nodes when constructing brain networks or…

计算机视觉与模式识别 · 计算机科学 2025-02-25 Minheng Chen , Chao Cao , Tong Chen , Yan Zhuang , Jing Zhang , Yanjun Lyu , Xiaowei Yu , Lu Zhang , Tianming Liu , Dajiang Zhu

The functional and structural representation of the brain as a complex network is marked by the fact that the comparison of noisy and intrinsically correlated high-dimensional structures between experimental conditions or groups shuns…

神经元与认知 · 定量生物学 2013-10-25 Tommaso Furlanello , Marco Cristoforetti , Cesare Furlanello , Giuseppe Jurman

Understanding the intricate architecture of brain networks and its connection to brain function is essential for deciphering the underlying principles of cognition and disease. While traditional graph-theoretical measures have been widely…

混沌动力学 · 物理学 2025-11-13 Anca Radulescu , Eva Kaslik , Alexandru Fikl , Johan Nakuci , Sarah Muldoon , Michael Anderson

Classification of biological neuron types and networks poses challenges to the full understanding of the brain's organisation and functioning. In this paper, we develop a novel objective classification model of biological neuronal types and…

神经元与认知 · 定量生物学 2020-03-31 Michael Taynnan Barros , Harun Siljak , Peter Mullen , Constantinos Papadias , Jari Hyttinen , Nicola Marchetti

Examining task-free functional connectivity (FC) in the human brain offers insights on how spontaneous integration and segregation of information relate to human cognition, and how this organization may be altered in different conditions,…

Small sample sizes in neuroimaging in general, and in structural connectome (SC) studies in particular limit the development of reliable biomarkers for neurological and psychiatric disorders - such as Alzheimer's disease and schizophrenia -…

The spatial topography of functional brain organization is increasingly recognized to play an important role in cognition and disease. Accounting for individual differences in functional topography is also crucial for accurately…

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