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Understanding the biological and behavioral heterogeneity underlying psychiatric disorders is critical for advancing precision diagnosis, treatment, and prevention. This paper addresses the scientific question of how multimodal data,…

统计方法学 · 统计学 2025-11-10 Yinjun Zhao , Yuanjia Wang , Ying LIu

We propose a novel inverse method that utilizes a set of data to construct a simple equation that governs the stochastic process for which the data have been measured, hence enabling us to reconstruct the stochastic process. As an example,…

统计力学 · 物理学 2007-05-23 J. Peinke , M. Reza Rahimi Tabar , Muhammad Sahimi , F. Ghasemi

We propose a Bayesian approach for model-based clustering of multivariate categorical data where variables are allowed to be associated within clusters and the number of clusters is unknown. The approach uses a two-layer mixture of finite…

统计方法学 · 统计学 2024-07-09 Gertraud Malsiner-Walli , Bettina Grün , Sylvia Frühwirth-Schnatter

In this paper, a methodology for the automated detection and classification of Tuberculosis(TB) is presented. Tuberculosis is a disease caused by mycobacterium which spreads through the air and attacks low immune bodies easily. Our…

人工智能 · 计算机科学 2011-08-05 Asha. T , S. Natarajan , K. N. B. Murthy

During deep sleep and under anaesthesia spontaneous patterns of cortical activation frequently take the form of slow travelling waves. Slow wave sleep is an important cognitive state especially because of its relevance for memory…

计算机视觉与模式识别 · 计算机科学 2024-01-23 Michael Gerstenberger , Dominic Juestel , Silviu Bodea

The goal of cluster analysis in survival data is to identify clusters that are decidedly associated with the survival outcome. Previous research has explored this problem primarily in the medical domain with relatively small datasets, but…

社会与信息网络 · 计算机科学 2017-03-10 S Chandra Mouli , Abhishek Naik , Bruno Ribeiro , Jennifer Neville

Clinical decision support systems (CDSSs) have been widely utilized to support the decisions made by cardiologists when detecting and classifying arrhythmia from electrocardiograms (ECGs). However, forming a CDSS for the arrhythmia…

信号处理 · 电气工程与系统科学 2023-10-16 Yun Kwan Kim , Minji Lee , Kunwook Jo , Hee Seok Song , Seong-Whan Lee

Cardiac arrhythmia is a prevalent and significant cause of morbidity and mortality among cardiac ailments. Early diagnosis is crucial in providing intervention for patients suffering from cardiac arrhythmia. Traditionally, diagnosis is…

信号处理 · 电气工程与系统科学 2020-04-14 Sricharan Vijayarangan , Balamurali Murugesan , Vignesh R , Preejith SP , Jayaraj Joseph , Mohansankar Sivaprakasam

After admission to emergency department (ED), patients with critical illnesses are transferred to intensive care unit (ICU) due to unexpected clinical deterioration occurrence. Identifying such unplanned ICU transfers is urgently needed for…

机器学习 · 计算机科学 2021-02-10 Chun-An Chou , Qingtao Cao , Shao-Jen Weng , Che-Hung Tsai

There is a growing proportion of people with several disease conditions ("multimorbidity"), placing increasing demands on healthcare systems. One hypothesis is that clusters of diseases may arise from shared underlying disease processes…

统计方法学 · 统计学 2025-08-15 Anthony J. Webster

Objective: Epileptic seizures are relatively common in critically-ill children admitted to the pediatric intensive care unit (PICU) and thus serve as an important target for identification and treatment. Most of these seizures have no…

Modern medicine requires generalised approaches to the synthesis and integration of multimodal data, often at different biological scales, that can be applied to a variety of evidence structures, such as complex disease analyses and…

定量方法 · 定量生物学 2019-11-11 Devin Taylor , Simeon Spasov , Pietro Liò

Parkinsons disease (PD) is a debilitating motor system disorder characterized by progressive loss of movement, tremors, and speech slurring. PD is due to the loss of dopamine-producing brain cells, and symptoms only worsen over time, making…

神经元与认知 · 定量生物学 2014-05-07 Pooja Chandrashekar

Machine learning algorithms for seizure detection have shown considerable diagnostic potential, with recent reported accuracies reaching 100%. Yet, only few published algorithms have fully addressed the requirements for successful clinical…

信号处理 · 电气工程与系统科学 2024-08-15 Nina Moutonnet , Steven White , Benjamin P Campbell , Saeid Sanei , Toshihisa Tanaka , Hong Ji , Danilo Mandic , Gregory Scott

Echocardiography is an essential medical technique for diagnosing cardiovascular diseases, but its high operational complexity has led to a shortage of trained professionals. To address this issue, we introduce a novel probe movement…

计算机视觉与模式识别 · 计算机科学 2025-10-13 Haojun Jiang , Teng Wang , Zhenguo Sun , Yulin Wang , Yang Yue , Yu Sun , Ning Jia , Meng Li , Shaqi Luo , Shiji Song , Gao Huang

Here we present DIVE: Data-driven Inference of Vertexwise Evolution. DIVE is an image-based disease progression model with single-vertex resolution, designed to reconstruct long-term patterns of brain pathology from short-term longitudinal…

Many coordination phenomena in Nature are grounded on a synchronisation regime. In the case of brain dynamics, such self-organised process allows the neurons of particular brain regions to behave as a whole and thus directly controlling the…

适应与自组织系统 · 物理学 2018-10-02 Malbor Asllani , Timoteo Carletti

It is well-known that mood and pain interact with each other, however individual-level variability in this relationship has been less well quantified than overall associations between low mood and pain. Here, we leverage the possibilities…

应用统计 · 统计学 2024-01-02 Rajenki Das , Mark Muldoon , Mark Lunt , John McBeth , Belay Birlie Yimer , Thomas House

Individual's general well-being is greatly impacted by mental health conditions including depression and Post-Traumatic Stress Disorder (PTSD), underscoring the importance of early detection and precise diagnosis in order to facilitate…

A BCI user awareness of an error is associated with a cortical signature named error-related potential (ErrP). The incorporation of ErrPs' detection in BCIs can improve BCIs' performance. This work is three-folded. First, we investigate if…

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