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One of the promising methods for the treatment of complex diseases such as cancer is combinational therapy. Due to the combinatorial complexity, machine learning models can be useful in this field, where significant improvements have…

机器学习 · 计算机科学 2020-01-08 Işıksu Ekşioğlu , Mehmet Tan

Despite deep neural network (DNN)'s impressive prediction performance in various domains, it is well known now that a set of DNN models trained with the same model specification and the same data can produce very different prediction…

机器学习 · 计算机科学 2020-08-18 Zhe Chen , Yuyan Wang , Dong Lin , Derek Zhiyuan Cheng , Lichan Hong , Ed H. Chi , Claire Cui

In clinical research, the lack of events of interest often necessitates imbalanced learning. One approach to resolve this obstacle is data integration or sharing, but due to privacy concerns neither is practical. Therefore, there is an…

机器学习 · 计算机科学 2020-09-01 Seok-Ju Hahn , Junghye Lee

In previous articles, we formalized the problem of optimal allocation strategies for a (perfect) vaccine in an infinite-dimensional metapopulation model. The aim of the current paper is to illustrate this theoretical framework with multiple…

最优化与控制 · 数学 2021-12-17 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

We present one-shot federated learning, where a central server learns a global model over a network of federated devices in a single round of communication. Our approach - drawing on ensemble learning and knowledge aggregation - achieves an…

机器学习 · 计算机科学 2019-03-07 Neel Guha , Ameet Talwalkar , Virginia Smith

Many datasets describing contacts in a population suffer from incompleteness due to population sampling and underreporting of contacts. Data-driven simulations of spreading processes using such incomplete data lead to an underestimation of…

物理与社会 · 物理学 2017-09-07 Julie Fournet , Alain Barrat

In this paper, we describe a dataset relating to cellular and physical conditions of patients who are operated upon to remove colorectal tumours. This data provides a unique insight into immunological status at the point of tumour removal,…

机器学习 · 计算机科学 2016-11-15 Chris Roadknight , Uwe Aickelin , John Scholefield , Lindy Durrant

We review vaccine efficacy (VE) estimands for susceptibility in individual randomized trials with natural (unmeasured) exposure, where individual responses are measured as time from vaccination until an event (e.g., disease from the…

统计方法学 · 统计学 2026-01-27 Michael P. Fay , Dean Follmann , Bruce J. Swihart , Lauren E. Dang

Wearing a face mask is one of the adjustments we had to follow to reduce the spread of the coronavirus. Having our faces covered by masks constantly has driven the need to understand and investigate how this behavior affects the recognition…

计算机视觉与模式识别 · 计算机科学 2022-10-11 Mohammed R. Al-Sinan , Aseel F. Haneef , Hamzah Luqman

Machine learning-based Deepfake detection models have achieved impressive results on benchmark datasets, yet their performance often deteriorates significantly when evaluated on out-of-distribution data. In this work, we investigate an…

计算机视觉与模式识别 · 计算机科学 2025-07-09 Haroon Wahab , Hassan Ugail , Lujain Jaleel

Ensemble learning, the machine learning paradigm where multiple algorithms are combined, has exhibited promising perfomance in a variety of tasks. The present work focuses on unsupervised ensemble classification. The term unsupervised…

机器学习 · 计算机科学 2020-12-22 Panagiotis A. Traganitis , Georgios B. Giannakis

Ensemble weather forecasts enable a measure of uncertainty to be attached to each forecast, by computing the ensemble's spread. However, generating an ensemble with a good spread-error relationship is far from trivial, and a wide range of…

大气与海洋物理 · 物理学 2021-01-05 Sebastian Scher , Gabriele Messori

For a long time, public health events, such as disease incidence or vaccination activity, have been monitored to keep track of the health status of the population, allowing to evaluate the effect of public health initiatives and to decide…

信息检索 · 计算机科学 2019-05-03 Niels Dalum Hansen

This paper presents a general and efficient framework for probabilistic inference and learning from arbitrary uncertain information. It exploits the calculation properties of finite mixture models, conjugate families and factorization. Both…

人工智能 · 计算机科学 2011-05-19 M. C. Garrido , P. E. Lopez-de-Teruel , A. Ruiz

If we can lower the number of people needed to vaccinate for a community to be immune against contagious diseases, we can save resources and life. A key to reach such a lower threshold of immunization is to find and vaccinate people who,…

种群与进化 · 定量生物学 2012-10-10 Sungmin Lee , Luis E. C. Rocha , Fredrik Liljeros , Petter Holme

Two observational methods are currently being used to monitor post-deployment vaccine effectiveness: the obvious crude method comparing rate testing positive per head of vaccinated population with that rate per head of unvaccinated…

统计方法学 · 统计学 2023-07-18 Roger F. Sewell

Determining whether vaccine efficacy wanes is important for individual and public decision making. Yet, quantification of waning is a subtle task. The classical approaches cannot be interpreted as measures of declining efficacy unless we…

统计方法学 · 统计学 2026-05-21 Gellért Perényi , Matias Janvin , Mats J. Stensrud

Vaccination is widely recognized as the most effective way of immunization against many infectious diseases. However, unfounded claims about supposed side effects of some vaccines have contributed to spread concern and fear among people,…

物理与社会 · 物理学 2014-12-03 A. D. Medus , C. O. Dorso

Real-world vaccine effectiveness has increasingly been studied using matching-based approaches, particularly in observational cohort studies following the target trial emulation framework. Although matching is appealing in its simplicity,…

统计方法学 · 统计学 2026-04-07 Emily Wu , Elizabeth Rogawski McQuade , Mats Stensrud , Razieh Nabi , David Benkeser

Mutual learning, in which multiple networks learn by sharing their knowledge, improves the performance of each network. However, the performance of ensembles of networks that have undergone mutual learning does not improve significantly…

计算机视觉与模式识别 · 计算机科学 2021-03-30 Naoki Okamoto , Soma Minami , Tsubasa Hirakawa , Takayoshi Yamashita , Hironobu Fujiyoshi