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Quality control in molecular optical sectioning microscopy is indispensable for transforming acquired digital images from qualitative descriptions to quantitative data. Although numerous tools, metrics, and phantoms have been developed,…

In Multiple-Input Multiple-Output (MIMO) systems, Sphere Decoding (SD) can achieve performance equivalent to full search Maximum Likelihood (ML) decoding, with reduced complexity. Several researchers reported techniques that reduce the…

信息论 · 计算机科学 2015-03-13 Boyu Li , Ender Ayanoglu

Scanning transmission X-ray microscopy (STXM) is a nanoscale imaging technique that can utilize several powerful contrast mechanisms for the quantitative mapping of chemical and physical materials properties. Spatial resolutions down to…

We report the development of a multichannel microscopy for whole-slide multiplane, multispectral, and phase imaging. We use trinocular heads to split the beam path into 6 independent channels and employ a camera array for parallel data…

While electron microscopy offers crucial atomic-resolution insights into structure-property relationships, radiation damage severely limits its use on beam-sensitive materials like proteins and 2D materials. To overcome this challenge, we…

计算机视觉与模式识别 · 计算机科学 2025-07-18 Zifei Wang , Zian Mao , Xiaoya He , Xi Huang , Haoran Zhang , Chun Cheng , Shufen Chu , Tingzheng Hou , Xiaoqin Zeng , Yujun Xie

In multi-photon microscopy (MPM), a recent in-vivo fluorescence microscopy system, the task of image restoration can be decomposed into two interlinked inverse problems: firstly, the characterization of the Point Spread Function (PSF) and…

图像与视频处理 · 电气工程与系统科学 2024-11-08 Julien Ajdenbaum , Emilie Chouzenoux , Claire Lefort , Ségolène Martin , Jean-Christophe Pesquet

In this work, we propose a simple transformer-based baseline for multimodal molecular representation learning, integrating three distinct modalities: SMILES strings, 2D graph representations, and 3D conformers of molecules. A key aspect of…

机器学习 · 计算机科学 2024-10-25 Andrei Manolache , Dragos Tantaru , Mathias Niepert

Medical image retrieval is essential for clinical decision-making and translational research, relying on discriminative visual representations. Yet, current methods remain fragmented, relying on separate architectures and training…

计算机视觉与模式识别 · 计算机科学 2025-09-03 Che Liu , Zheng Jiang , Chengyu Fang , Heng Guo , Yan-Jie Zhou , Jiaqi Qu , Le Lu , Minfeng Xu

Multi-contrast MRI methods acquire multiple images with different contrast weightings, which are used for the differentiation of the tissue types or quantitative mapping. However, the scan time needed to acquire multiple contrasts is…

图像与视频处理 · 电气工程与系统科学 2025-02-18 Yan Chen , Jyothi Rikhab Chand , Steven R. Kecskemeti , James H. Holmes , Mathews Jacob

Structured illumination microscopy (SIM) reconstructs a super-resolved image from multiple raw images captured with different illumination patterns; hence, acquisition speed is limited, making it unsuitable for dynamic scenes. We propose a…

光学 · 物理学 2025-06-17 Ruiming Cao , Fanglin Linda Liu , Li-Hao Yeh , Laura Waller

We present an approach for two-dimensional (2D) imaging through a single single-mode or multimode fiber without the need for scanners. A random scattering medium placed next to the distal end of the fiber is used to encode the collected…

光学 · 物理学 2014-11-04 Sylwia M. Maliszewska , Ori Katz , Mathias Fink , Sylvain Gigan

We propose a speed-up method for the in-focus plane detection in digital holographic microscopy that can be applied to a broad class of autofocusing algorithms that involve repetitive propagation of an object wave to various axial locations…

定量方法 · 定量生物学 2023-05-19 Julianna Winnik , Damian Suski , Piotr Zdańkowski , Luiza Stanaszek , Vicente Micó , Maciej Trusiak

3D super-resolution fluorescence microscopy typically requires sophisticated setups, sample preparation, or long measurements. A notable exception, SOFI, only requires recording a sequence of frames and no hardware modifications whatsoever…

光学 · 物理学 2024-03-01 Pawel Szczypkowski , Monika Pawlowska , Radek Lapkiewicz

Non-destructive testing and medical diagnostic techniques using ultrasound has become indispensable in evaluating the state of materials or imaging the internal human body, respectively. To conduct spatially resolved high-quality…

应用物理 · 物理学 2023-07-17 Wei Wang , Jie Hu , Jingjing Liu , Yang Tan , Jing Yang , Bin Liang , Johan Christensen , Jianchun Cheng

In clinical practice, 2D magnetic resonance (MR) sequences are widely adopted. While individual 2D slices can be stacked to form a 3D volume, the relatively large slice spacing can pose challenges for both image visualization and subsequent…

图像与视频处理 · 电气工程与系统科学 2024-06-11 Xin Wang , Zhiyun Song , Yitao Zhu , Sheng Wang , Lichi Zhang , Dinggang Shen , Qian Wang

Single-beam super-resolution microscopy, also known as superlinear microscopy, exploits the nonlinear response of fluorescent probes in confocal microscopy. The technique requires no complex purpose-built system, light field modulation, or…

Image sensors are the backbone of many imaging technologies of great importance to modern sciences, being particularly relevant in biomedicine. An ideal image sensor should be usable through all the electromagnetic spectrum (large…

医学物理 · 物理学 2022-03-16 Juan Aguirre

Three-dimensional segmentation in magnetic resonance images (MRI), which reflects the true shape of the objects, is challenging since high-resolution isotropic MRIs are rare and typical MRIs are anisotropic, with the out-of-plane dimension…

图像与视频处理 · 电气工程与系统科学 2023-03-15 Hanxue Gu , Hongyu He , Roy Colglazier , Jordan Axelrod , Robert French , Maciej A Mazurowski

PURPOSE: Interactive cardiac magnetic resonance imaging is used for fast scan planning and MR guided interventions. However, the requirement for real-time acquisition and near real-time visualization constrains the achievable…

计算机视觉与模式识别 · 计算机科学 2024-09-01 Olivier Jaubert , Javier Montalt-Tordera , Daniel Knight , Pr. Simon Arridge , Jennifer Steeden , Pr. Vivek Muthurangu

One of the main characteristics of optical imaging systems is the spatial resolution, which is restricted by the diffraction limit to approximately half the wavelength of the incident light. Along with the recently developed classical…

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