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A detailed experimental and simulation study of the extraction of a 24 keV He-ion beam from an ECR ion source and the subsequent beam transport through an analyzing magnet is presented. We find that such a slow ion beam is very sensitive to…

加速器物理 · 物理学 2015-06-04 S. Saminathan , J. P. M. Beijers , H. R. Kremers , V. Mironov , J. Mulder , S. Brandenburg

Particle physics simulations are the cornerstone of nuclear engineering applications. Among them radiotherapy (RT) is crucial for society, with 50% of cancer patients receiving radiation treatments. For the most precise targeting of tumors,…

机器学习 · 计算机科学 2021-09-10 Oscar Pastor-Serrano , Zoltán Perkó

Arrays of minibeams of protons and $^{12}$C in tissue-like media were modeled with Geant4 toolkit. A set of beam energies was used in simulations to provide a Spead-out Bragg peak (SOBP) extended by 6 cm in depth for protons as well as for…

医学物理 · 物理学 2024-09-23 I. A. Pshenichnov , U. A. Dmitrieva , S. D. Savenkov , A. O. Svetlichnyi

We model the responses of Tissue-Equivalent Proportional Counters (TEPC) to radiation fields of therapeutic C-12 beams in a water phantom and to quasi-monoenergetic neutrons in a PMMA phantom. Simulations are performed with the Monte Carlo…

医学物理 · 物理学 2013-07-09 Lucas Burigo , Igor Pshenichnov , Igor Mishustin , Marcus Bleicher

Previously reported nanodosimetric measurements of therapeutic-energy carbon ions penetrating simulated tissue have produced results that are incompatible with the predicted mean energy of the carbon ions in the nanodosimeter and previous…

医学物理 · 物理学 2025-10-27 Miriam Schwarze , Gerhard Hilgers , Hans Rabus

In this study, two proton beam delivery designs, passive scattering proton therapy (PSPT) and pencil beam scanning (PBS), were quantitatively compared in terms of dosimetric indices. The GATE Monte Carlo code was used to simulate the proton…

医学物理 · 物理学 2022-09-21 A. Asadi , A. Akhavanallaf , S. A. Hosseini , H. Zaidi

Microdosimetric single event spectra is a significant parameter in radiotherapy, which can be used to evaluate the biological effect of radiation fields. This paper simulated microscopic patterns of energy depositions for mixed radiation…

医学物理 · 物理学 2015-02-03 Chengguo Pang , Junkui Xu , Wuyuan Li , Weiwei Yan , Zeen Yao , Youwu Su

The present work is devoted to develop a computational model using the Gate Monte Carlo software for the simulation of a 6MV photon beam given by Elekta Synergy Platform medical linear accelerator treatment head. The model includes the…

医学物理 · 物理学 2013-09-04 Yahya Tayalati , Samir Didi , Mustafa Zerfaoui , Abdellilah Moussaa

Radiotherapy using very high-energy electron (VHEE) beams generated by a laser-plasma accelerator has garnered significant interest due to its dose distribution capabilities and potential to address limitations of traditional photon-based…

Given that there are 94 clinics and more than 200,000 patients treated worldwide, proton and carbon are the most used heavily charged particles in heavy ion therapy. However, there is a recent increasing trend in using new ion beams. Each…

医学物理 · 物理学 2021-01-26 Fatih Ekinci , Erkan Bostanci , Ozlem Dagli , Mehmet Serdar Guzel

Molecular beam epitaxy (MBE) is an epitaxy method for thin film deposition of single crystals. MBE is widely used in the manufacture of semiconductor devices, including transistors, and it is considered one of the fundamental tools for the…

材料科学 · 物理学 2025-01-03 Ganesh Aryal

The radiation effects induced by Co60 serve as a reference system for the consideration of LET and RBE in normal and tumor tissue dose-effect relations are usually handled by the linear-quadratic model (LQ). This approximation excellently…

医学物理 · 物理学 2018-01-09 Waldemar Ulmer

Carbon ion radiotherapy is known as a less invasive cancer treatment. The radiation quality is an important parameter to evaluate the biological effect and the clinical dose from the measured physical dose. The performance of SOPHIAS…

医学物理 · 物理学 2015-07-31 Akihiko Matsumura

Mandible Osteoradionecrosis (ORN) is one of the most severe adverse events (AEs) for head and neck (H&N) cancer radiotherapy. Previous retrospective investigations on real-world data relied on conventional statistical models that primarily…

During low-energy operations below the regular injection energy in the Relativistic Heavy Ion Collider (RHIC), significant beam lifetime reductions due to the beam-beam interaction in conjunction with large space charge tune shifts have…

加速器物理 · 物理学 2014-10-16 C. Montag , A. Fedotov

Electromagnetic radiation (photons) or particle beam (protons or heavy ions) have similar biological effects, i.e. damage to human cell DNA that eventually leads to cell death if not correctly repaired. The biological effects at the level…

医学物理 · 物理学 2018-04-24 Pierre Scalliet , John Gueulette

A recent experimental observation has shown efficient transport of Mega Ampere of electron currents through aligned carbon nanotube arrays [Phys. Rev Letts. 108, 235005 (2012)]. The result was subsequently interpreted on the basis of…

等离子体物理 · 物理学 2015-09-02 Chandrashekhar Shukla , Amita Das , Kartik Patel

The high-intensity rare-isotope accelerator (RAON) of the Rare Isotope Science Project (RISP) in Daejeon, Korea, has been designed to accelerate multiple-charge-state beams. The ion beams, which are generated by Electron Cyclotron Resonance…

加速器物理 · 物理学 2015-07-29 Hyunchang Jin , Ji-Ho Jang

The Monte Carlo method is widely used in the Gamma Knife dose distribution calculations. In this study, Monte-Carlo simulation with Geant4 was applied to determine Leksell Gamma Knife dose distribution for homogeneous solid water and…

医学物理 · 物理学 2021-01-26 Ozlem Dagli , A. Gunes Tanir , Gokhan Kurt

Radiotherapy with heavy ions, in particular, 12C beams, is one of the most advanced forms of cancer treatment. Sharp dose gradients and high biological effectiveness in the target region make them an ideal tool to treat deep-seated and…