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Treating cancer is one of the most challenging task in medical sciences. Only limited types of cancer treatments are available as their study is still ongoing. The earlier therapies like radiotherapy with x-rays, chemotherapy are associated…

加速器物理 · 物理学 2024-06-06 R. Kanishka

Radioactive ion beams (RIB) are a key focus of current research in nuclear physics. Already long ago it was proposed that they could have applications in cancer therapy. In fact, while charged particle therapy is potentially the most…

Interaction Vertex Imaging (IVI) is used for range monitoring (RM) in carbon ion radiotherapy. The purpose of RM is to measure the Bragg peak (BP) position for each contributing beam, and detect any changes. Currently, there is no consensus…

The effective use of swift ion beams in cancer treatment (known as hadrontherapy) as well as an appropriate protection in manned space missions rely on the accurate understanding of energy delivery to cells damaging their genetic…

For radiation protection and environmental impact assessment purpose, the radioactivity induced by carbon ion of Heavy Ion Medical Machine (HIMM) was studied. Radionuclides in accelerator component, cooling water and air at target area…

仪器与探测器 · 物理学 2013-12-31 Xu Jun-Kui , Su You-Wu , Li Wu-Yuan , Mao Wang , Xia Jia-Wen , Chen Xi-Meng , Yan Wei-Wei , Xu Chong

The cooling storage ring external-target experiment is a large-scale nuclear physics experiment, which aims to study the physics of heavy-ion collisions at low temperatures and high baryon densities. A beam monitor (BM) is placed in the…

Purpose: Retinoblastoma (RB) is the most common eye tumor in childhood and can be treated external radiotherapy. The purpose of this work is to evaluate the adequacy of Monte Carlo simulations and the accuracy of a commercial treatment…

医学物理 · 物理学 2018-09-26 L. Brualla , P. A. Mayorga , A. Flühs , A. M. Lallena , J. Sempau , W. Sauerwein

Radiation therapy is one of the most common cancer treatments, and dose optimization and targeting of radiation are crucial since both cancerous and healthy cells are affected. Different mathematical and computational approaches have been…

生物物理 · 物理学 2025-11-07 Mirko Bagnarol , Gianluca Lattanzi , Jan Åström , Mikko Karttunen

We have determined the depth-dose curve, the penetration range, and the water equivalent ratio (WER), for proton beams of clinical energies in cortical bone, by means of a detailed and accurate simulation that combines molecular dynamics…

医学物理 · 物理学 2024-09-18 Ana María Zamora-Vinaroz , Pablo de Vera , Isabel Abril , Rafael Garcia-Molina

Carbon ion therapy is one of the most advanced forms of radiotherapy, promising improved efficacy against resistant cancers. However, the high precision offered by the carbon ion Bragg peak requires precise knowledge of the beam range…

To develop a machine learning-based framework for accurately modeling the anode heel effect in Monte Carlo simulations of X-ray imaging systems, enabling realistic beam intensity profiles with minimal experimental calibration. Multiple…

医学物理 · 物理学 2026-01-07 Hussein Harb , Didier Benoit , Axel Rannou , Chi-Hieu Pham , Valentin Tissot , Bahaa Nasr , Julien Bert

A broad-beam-delivery system for heavy-charged-particle radiotherapy often employs multiple collimators and a range-compensating filter, which potentially offer complex beam customization. In treatment planning, it is however difficult for…

医学物理 · 物理学 2012-01-11 Nobuyuki Kanematsu

Aims. Determination of K- and L-shell cross sections of the carbon atom and ions using the modified relativistic binary encounter Bethe (MRBEB) method, a simple analytical scheme based on one atomic parameter that allows determining…

We present MONAS (MicrOdosimetry-based modelliNg for relative biological effectiveness (RBE) ASsessment) toolkit. MONAS is a TOPAS Monte Carlo extension, that combines simulations of microdosimetric distributions with radiobiological…

Purpose: To describe the dosimetric commissioning and quality assurance (QA) of the actively scanned proton and carbon ion beams at the Italian National Center for Oncological Hadrontherapy. Methods: The laterally integrated…

The K130 Room Temperature Cyclotron (RTC) at the Variable Energy Cyclotron Centre (VECC), Kolkata has delivered a variety of ion beams for experimental programs with stable performance since the 1970s. The extracted beams are transported to…

加速器物理 · 物理学 2026-03-30 Arup Ratan Jana , Animesh Goswami , Malay Kanti Dey

The diverse near-Earth radiation environment due to cosmic rays and solar radiation has direct impact on human civilization. In the present and upcoming era of increasing air transfer, it is important to have precise idea of radiation dose…

医学物理 · 物理学 2021-12-16 Abhijit Roy , Ritabrata Sarkar , Choonsik Lee

The use of very high energy electron (VHEE) beams for radiotherapy has been actively studied for over two decades due to their advantageous dose distribution, deep penetration depth and great potential of ultra-high dose-rate irradiation.…

医学物理 · 物理学 2026-04-30 Bing Zhou , Zhiyuan Guo , Yang Wan , Shuang Liu , Jianfei Hua , Wei Lu

In order to investigate the longitudinal beam dynamics during the adiabatic capture and acceleration processes of the CRing in HIAF project, a simulation of both processes above is carried out with $U^{34+}$ ions. The ions will be captured…

加速器物理 · 物理学 2014-10-14 Peng Shang , Da-yu Yin , Jia-wen Xia , Jian-cheng Yang , Guo-feng Qu , Wen-heng Zheng , Zhong-shan Li , Shuang Ruan

A model for beam customization with collimators and a range-compensating filter based on the phase-space theory for beam transport is presented for dose distribution calculation in treatment planning of radiotherapy with protons and heavier…

医学物理 · 物理学 2008-05-27 Nobuyuki Kanematsu , Shunsuke Yonai , Azusa Ishizaki , Masami Torikoshi