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The heartbeat is mediated between cardiac cells by waves of electrical depolarisation. During cardiac arrhythmias, electrical activity was found to be organised in scroll waves which rotate around a dynamical filament curve. In this thesis,…

生物物理 · 物理学 2015-11-13 Hans J. F. M. Dierckx

Scroll waves are three-dimensional excitation patterns that rotate around a central filament curve; they occur in many physical, biological and chemical systems. We explicitly derive the equations of motion for scroll wave filaments in…

软凝聚态物质 · 物理学 2014-08-20 Hans Dierckx , Henri Verschelde

Three-dimensional excitable systems can create nonlinear scroll waves that rotate around one-dimensional phase singularities. Recent theoretical work predicts that these filaments drift along step-like height variations. Here we test this…

斑图形成与孤子 · 物理学 2015-03-19 Hua Ke , Zhihui Zhang , Oliver Steinbock

A scroll wave in a sufficiently thin layer of an excitable medium with negative filament tension can be stable nevertheless due to filament rigidity. Above a certain critical thickness of the medium, such scroll wave will have a tendency to…

斑图形成与孤子 · 物理学 2015-06-05 Hans Dierckx , Henri Verschelde , Ozgur Selsil , Vadim Biktashev

In many oscillatory or excitable systems, dynamical patterns emerge which are stationary or periodic up in a moving frame of reference. Examples include traveling waves or spiral waves in chemical systems or cardiac tissue. We present a…

斑图形成与孤子 · 物理学 2019-03-06 Hans Dierckx , Alexander V. Panfilov , Henri Verschelde , Vadim N. Biktashev , Irina V. Biktasheva

Quiescent filaments are usually affected by internal and/or external perturbations triggering oscillations of different kinds. In particular, external large-scale coronal waves can perturb remote quiescent filaments leading to…

Abnormal electrical activity from the boundaries of ischemic cardiac tissue is recognized as one of the major causes in generation of ischemia-reperfusion arrhythmias. Here we present theoretical analysis of the waves of electrical activity…

组织与器官 · 定量生物学 2015-05-19 Vadim N. Biktashev , Irina V. Biktasheva , Narine A. Sarvazyan

Three-dimensional excitable systems can selforganize vortex patterns that rotate around one-dimensional phase singularities called filaments. In experiments with the Belousov-Zhabotinsky reaction and numerical simulations, we pin these…

斑图形成与孤子 · 物理学 2015-04-08 Hua Ke , Zhihui Zhang , Oliver Steinbock

A scroll wave in a very thin layer of excitable medium is similar to a spiral wave, but its behaviour is affected by the layer geometry. We identify the effect of sharp variations of the layer thickness, which is separate from filament…

斑图形成与孤子 · 物理学 2015-02-13 I. V. Biktasheva , H. Dierckx , V. N. Biktashev

Initially straight slender elastic rods with geometrically constrained ends buckle and form stable two-dimensional shapes when compressed by bringing the ends together. It is also known that beyond a critical value of the pre-stress,…

斑图形成与孤子 · 物理学 2021-02-03 Soheil Fatehiboroujeni , Arvind Gopinath , Sachin Goyal

Turbulence of scroll waves is a sort of spatio-temporal chaos that exists in three-dimensional excitable media. Cardiac tissue and the Belousov-Zhabotinsky reaction are examples of such media. In cardiac tissue, chaotic behaviour is…

斑图形成与孤子 · 物理学 2009-11-13 S. W. Morgan , I. V. Biktasheva , V. N. Biktashev

I present the numerical computation of speed and direction of the drift of a spiral wave in an excitable medium in the presence of an electric field. In contrast to earlier results, the drift speed presents a strong variation close to the…

软凝聚态物质 · 物理学 2007-05-23 Herve Henry

We study a simple two-dimensional model for motion of an elastic filament subject to internally generated stresses and show that wave-like propagating shapes which can propel the filament can be induced by a self-organized mechanism via a…

软凝聚态物质 · 物理学 2019-08-17 S. Camalet , F. Julicher , J. Prost

Cardiac tissue and the Belousov-Zhabotinsky reaction provide two notable examples of excitable media that support scroll waves, in which a filament core is the source of spiral waves of excitation. Here we consider a novel topological…

Excitable media are ubiquitous in nature, and in such systems the local excitation tends to self-organize in traveling waves, or in rotating spiral-shaped patterns in two or three spatial dimensions. Examples include waves during a pandemic…

The breakup of rotating scroll waves in three-dimensional excitable media has been linked to important biological processes. The known mechanisms for this transition almost exclusively involve the dynamics of the scroll filament, i.e., the…

斑图形成与孤子 · 物理学 2011-09-29 S. Sridhar , Anitna Ghosh , Sitabhra Sinha

Nonlinear waves of the reaction-diffusion (RD) type occur in many biophysical systems, including the heart, where they initiate cardiac contraction. Such waves can form vortices called scroll waves, which result in the onset of…

生物物理 · 物理学 2016-12-21 R. Majumder , R Pandit , A. V. Panfilov

We investigate stability and dynamics of higher-order solitary waves in quadratic media, which have a central peak and one or more surrounding rings. We show existence of two qualitatively different behaviours. For positive phase mismatch…

patt-sol · 物理学 2007-05-23 Dmitry V. Skryabin , William J. Firth

Fibroblast-myocyte coupling can modulate electrical-wave dynamics in cardiac tissue. In diseased hearts, the distribution of fibroblasts is heterogeneous, so there can be gradients in the fibroblast density (henceforth we call this GFD)…

生物物理 · 物理学 2017-01-04 Soling Zimik , Rahul Pandit

Rotating spiral and scroll waves (vortices) are investigated in the FitzHugh-Nagumo model of excitable media. The focus is on a parameter region in which there exists bistability between alternative stable vortices with distinct periods.…

斑图形成与孤子 · 物理学 2015-05-19 Andrew J. Foulkes , Dwight Barkley , Vadim N. Biktashev , Irina V. Biktasheva
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