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In the boundary layer of multicomponent fluid mixtures, the species-specific mass flux in the wall-normal direction is determined by the combination of turbulent-diffusiophoretic diffusion due to composition gradients, and diffusion due to…

流体动力学 · 物理学 2018-08-10 Sverre G. Johnsen

Neural encoding is a field in neuroscience that focuses on characterizing how information from stimuli is encoded in the spiking activity of neurons. When more than one stimulus is present, a theory known as multiplexing posits that neurons…

统计方法学 · 统计学 2025-03-12 Nicholas Marco , Jennifer M. Groh , Surya T. Tokdar

Within cells, vesicles and proteins are actively transported several micrometers along the cytoskeletal filaments. The transport along microtubules is propelled by dynein and kinesin motors, which carry the cargo in opposite directions.…

生物物理 · 物理学 2020-05-20 Robin Jose , Ludger Santen

Biofilament-motor protein complexes are ubiquitous in biology and drive the transport of cargo vital for many fundamental cellular processes. As they move, motor proteins exert compressive forces on the filaments to which they are attached,…

生物物理 · 物理学 2024-06-12 Bethany Clarke , Yongyun Hwang , Eric Keaveny

Molecular motion through pores plays a crucial role in various natural and industrial processes. One of the most fascinating features of biological channel-facilitated transport is a stochastic gating process, when the channels dynamically…

化学物理 · 物理学 2018-12-20 Aram Davtyan , Anatoly B. Kolomeisky

We consider the dynamics of a bio-filament under the collective drive of motor proteins. They are attached irreversibly to a substrate and undergo stochastic attachment-detachment with the filament to produce a directed force on it. We…

软凝聚态物质 · 物理学 2023-05-12 Chitrak Karan , Debasish Chaudhuri

Multivalent cargo that can interact with substrates via multiple interaction sites exhibit shared characteristics despite being found in different systems at different length-scales. Here, a general analytical model has been developed that…

亚细胞过程 · 定量生物学 2021-11-16 Lewis Scott Mosby , Anne Straube , Marco Polin

Using a simple theoretical model of a nanoscale asymmetric particle/molecule with asymmetric structure or/and asymmetric charge distribution, here using a charge dipole as an example, we show that there is unidirectional transportation…

介观与纳米尺度物理 · 物理学 2013-08-20 Yusong Tu , Nan Sheng , Rongzheng Wan , Haiping Fang

Using a nonperturbative classical model for ionic motion through one-dimensional (1D) solids, we explore how thermal lattice vibrations affect ionic transport properties. Based on analytic and numerical calculations, we find that the mean…

介观与纳米尺度物理 · 物理学 2023-09-27 Harshitra Mahalingam , Ben Andrew Olsen , Aleksandr Rodin

Shearing granular materials induces non-affine displacements. Such non-affine displacements have been studied extensively, and are known to correlate with plasticity and other mechanical features of amorphous packings. A well known example…

软凝聚态物质 · 物理学 2020-12-15 Dong Wang , Joshua A. Dijksman , Jonathan Bares , Jie Ren , Hu Zheng

Heat dissipation is ubiquitous in living systems, which constantly convert distinct forms of energy into each other. The transport of thermal energy in liquids and even within proteins is well understood but kinetic energy transfer across a…

软凝聚态物质 · 物理学 2026-01-07 Brandon Neff , Matthias Heyden

In recent literature there has been a lot of interest in the phenomena of noise induced transport in the absence of an average bias occurring in spatially periodic systems far from equilibrium. One of the main motivations in this area is to…

生物物理 · 物理学 2007-05-23 Raishma Krishnan , A. M. Jayannavar

The transport of individual entities through interconnected structures is a process of practical relevance both in biology and technology. Examples are given by diffusive dynamics of molecules in porous structures. In soft environments,…

软凝聚态物质 · 物理学 2026-02-09 Jakob Mihatsch , Andreas M. Menzel

Single kinesin molecular motors can processively move along a microtubule (MT) a few micrometers on average before dissociating. However, cellular length scales over which transport occurs are several hundred microns and more. Why seemingly…

亚细胞过程 · 定量生物学 2019-08-21 Keshav B. Patel , Shengtan Mao , M. Gregory Forest , Samuel K. Lai , Jay M. Newby

We analyze experimental observations of microtubules undergoing small fluctuations about a "balance point" when mixed in solution of two different kinesin motor proteins, KLP61F and Ncd. It has been proposed that the microtubule movement is…

细胞行为 · 定量生物学 2013-07-24 J. M. Deutsch , Ian P. Lewis

Mechanochemical coupling was studied for two different types of myosin motors in cells: myosin V, which carries cargo over long distances by as a single molecule; and myosin II, which generates a contracting force in cooperation with other…

亚细胞过程 · 定量生物学 2009-11-13 Masatoshi Nishikawa , Hiroaki Takagi , Atsuko H. Iwane , Toshio Yanagida

Cytoplasmic dynein exhibits a directional processive movement on microtubule filaments and is known to move in steps of varying length based on the number of ATP molecules bound to it and the load that it carries. It is experimentally…

生物物理 · 物理学 2014-08-22 S. Sumathy , S. V. M. Satyanarayana

We study the model of a molecular switch comprised of a molecule with a soft vibrational degree of freedom coupled to metallic leads. In the presence of strong electron-ion interaction, different charge states of the molecule correspond to…

介观与纳米尺度物理 · 物理学 2008-12-18 Fabio Pistolesi , Yaroslav M. Blanter , Ivar Martin

Microscopic biological systems operate far from equilibrium, are subject to strong fluctuations, and are composed of many coupled components with interactions varying in nature and strength. Researchers are actively investigating the…

统计力学 · 物理学 2023-12-25 Emma Lathouwers , David A. Sivak

Diffusive transport of particles or, more generally, small objects is a ubiquitous feature of physical and chemical reaction systems. In configurations containing confining walls or constrictions transport is controlled both by the…

统计力学 · 物理学 2009-01-22 P. Sekhar Burada , Peter Hanggi , Fabio Marchesoni , Gerhard Schmid , Peter Talkner
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