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We study the problem of causal discovery through targeted interventions. Starting from few observational measurements, we follow a Bayesian active learning approach to perform those experiments which, in expectation with respect to the…

机器学习 · 统计学 2019-10-10 Julius von Kügelgen , Paul K Rubenstein , Bernhard Schölkopf , Adrian Weller

A major shortcoming of medical practice is the lack of an objective measure of conscious level. Impairment of consciousness is common, e.g. following brain injury and seizures, which can also interfere with sensory processing and volitional…

神经元与认知 · 定量生物学 2025-12-24 Alexis Pomares Pastor , Ines Ribeiro Violante , Gregory Scott

Identifying what aspects of brain activity are responsible for conscious perception remains one of the most challenging problems in science. While progress has been made through psychophysical studies employing EEG and fMRI, research would…

神经元与认知 · 定量生物学 2025-07-14 Daniel K. Freeman , Brian Odegaard , Seung-Schik Yoo , Matthias Michel

Active policy search combines the trial-and-error methodology from policy search with Bayesian optimization to actively find the optimal policy. First, policy search is a type of reinforcement learning which has become very popular for…

机器人学 · 计算机科学 2024-02-13 Ruben Martinez-Cantin

We propose an efficient transfer Bayesian optimization method, which finds the maximum of an expensive-to-evaluate black-box function by using data on related optimization tasks. Our method uses auxiliary information that represents the…

机器学习 · 统计学 2019-09-18 Tomoharu Iwata , Takuma Otsuka

This study focuses on Multi-Channel Transcranial Electrical Stimulation, a non-invasive brain method for stimulating neuronal activity under the influence of low-intensity currents. We introduce mathematical formulation for finding a…

最优化与控制 · 数学 2022-06-06 Fernando Galaz Prieto , Atena Rezaei , Maryam Samavaki , Sampsa Pursiainen

Functional magnetic resonance imaging (fMRI) enables indirect detection of brain activity changes via the blood-oxygen-level-dependent (BOLD) signal. Conventional analysis methods mainly rely on the real-valued magnitude of these signals.…

统计方法学 · 统计学 2023-10-31 Zhengxin Wang , Daniel B. Rowe , Xinyi Li , D. Andrew Brown

Objective: Numerical modeling of electric fields induced by transcranial alternating current stimulation (tACS) is currently a part of the standard procedure to predict and understand neural response. Quasi-static approximation for electric…

Understanding how external stimuli are encoded in distributed neural activity is of significant interest in clinical and basic neuroscience. To address this need, it is essential to develop analytical tools capable of handling limited data…

机器学习 · 计算机科学 2024-09-11 Navid Ziaei , Reza Saadatifard , Ali Yousefi , Behzad Nazari , Sydney S. Cash , Angelique C. Paulk

Analysis of brain imaging scans is critical to understanding the way the human brain functions, which can be leveraged to treat injuries and conditions that affect the quality of life for a significant portion of the human population. In…

统计方法学 · 统计学 2022-03-02 Daniel Spencer , David Bolin , Mary Beth Nebel , Amanda Mejia

Electroencephalography (EEG)-based P300 brain-computer interfaces (BCIs) enable communication without physical movement by detecting stimulus-evoked neural responses. Accurate and efficient decoding remains challenging due to high…

统计方法学 · 统计学 2026-03-02 Guoxuan Ma , Yuan Zhong , Moyan Li , Yuxiao Nie , Jian Kang

Procrastination represents one of the most prevalent behavioral problems associated with individual health and societal productivity. Despite its high prevalence and substantial impact on daily functioning, its underlying neurocognitive…

Accurate neuronavigation is critical for effective transcranial magnetic stimulation (TMS), as stimulation outcomes depend directly on precise coil placement. Existing neuronavigation systems are often costly, complex, and prone to tracking…

人机交互 · 计算机科学 2026-01-26 Xuyi Hu , Ke Ma , Siwei Liu , Per Ola Kristensson , Stefan Goetz

We present a real-time visualization system for Transcranial Magnetic Stimulation (TMS), a non-invasive neuromodulation technique for treating various brain disorders and mental health diseases. Our solution targets the current challenges…

信号处理 · 电气工程与系统科学 2024-03-14 Loraine Franke , Tae Young Park , Jie Luo , Yogesh Rathi , Steve Pieper , Lipeng Ning , Daniel Haehn

The main objective of the electrical stimulation of the brain is to generate action potentials from the application of electromagnetic fields. Among the available techniques, transcranial electrical stimulation (TES) represents a popular…

医学物理 · 物理学 2015-11-09 Carlos G. Tarazona , Carlos E. Guerra , Laura Chávez , Sebastián Andrade

Neurodevelopmental disorders such as Fragile X Syndrome (FXS) and Autism Spectrum Disorder (ASD) are characterized by disrupted cortical oscillatory activity, particularly in the alpha and gamma frequency bands. These abnormalities are…

神经元与认知 · 定量生物学 2025-11-14 Zag ElSayed , Grace Westerkamp , Jack Yanchen Liu , Ernest Pedapati

Transcranial ultrasonic stimulation (TUS) is rapidly gaining traction for non-invasive human neuromodulation, with a pressing need to establish protocols that maximise neuromodulatory efficacy. In this review, we aggregate and examine…

生物物理 · 物理学 2024-07-04 Tulika Nandi , Benjamin R. Kop , Kim Butts Pauly , Charlotte J. Stagg , Lennart Verhagen

Bayesian adaptive designs enable flexible clinical trials by adapting features based on accumulating data. Among these, Bayesian Response-Adaptive Randomization (BRAR) skews patient allocation towards more promising treatments based on…

统计方法学 · 统计学 2025-12-05 Daniel Kaddaj , Stef Baas , Edwin Y. N. Tang , David S. Robertson , Lukas Pin , Sofía S. Villar

Detecting shared neural activity from functional magnetic resonance imaging (fMRI) across individuals exposed to the same stimulus can reveal synchronous brain responses, functional roles of regions, and potential clinical biomarkers.…

应用统计 · 统计学 2026-04-24 Spencer Wadsworth , Nabin Koirala , Nicole Landi , Ofer Harel

Research on transcranial magnetic stimulation (TMS) combined with encephalography feedback (EEG-TMS) has shown that the phase of the sensorimotor mu rhythm is predictive of corticospinal excitability. Thus, if the subject-specific optimal…

神经元与认知 · 定量生物学 2024-10-10 Miriam Kirchhoff , Dania Humaidan , Ulf Ziemann