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Whether, when, and how causal interactions between neurons can be meaningfully studied from observations of neural activity alone are vital questions in neural data analysis. Here we aim to better outline the concept of functional…

神经元与认知 · 定量生物学 2023-12-05 Ian H. Stevenson

Maximum entropy methods provide a principled path connecting measurements of neural activity directly to statistical physics models, and this approach has been successful for populations of $N\sim 100$ neurons. As $N$ increases in new…

生物物理 · 物理学 2023-10-18 Christopher W. Lynn , Qiwei Yu , Rich Pang , William Bialek , Stephanie E. Palmer

Plasticity is one of the most important properties of the nervous system, which enables animals to adjust their behavior to the ever-changing external environment. Changes in synaptic efficacy between neurons constitute one of the major…

神经元与认知 · 定量生物学 2018-01-23 Taishi Iwasaki , Hideitsu Hino , Masami Tatsuno , Shotaro Akaho , Noboru Murata

Learning causal relationships from time series data is an important but challenging problem. Existing synthetic datasets often contain hidden artifacts that can be exploited by causal discovery methods, reducing their usefulness for…

机器学习 · 计算机科学 2026-03-23 Xiaoyu He , Petr Ryšavý , Jakub Mareček

Ultrasound imaging is caught between the quest for the highest image quality, and the necessity for clinical usability. Our contribution is two-fold: First, we propose a novel fully convolutional neural network for ultrasound…

计算机视觉与模式识别 · 计算机科学 2019-04-10 Walter Simson , Rüdiger Göbl , Magdalini Paschali , Markus Krönke , Klemens Scheidhauer , Wolfgang Weber , Nassir Navab

Big science initiatives are trying to reconstruct and model the brain by attempting to simulate brain tissue at larger scales and with increasingly more biological detail than previously thought possible. The exponential growth of parallel…

性能 · 计算机科学 2020-06-25 Francesco Cremonesi , Georg Hager , Gerhard Wellein , Felix Schürmann

We study pairwise Ising models for describing the statistics of multi-neuron spike trains, using data from a simulated cortical network. We explore efficient ways of finding the optimal couplings in these models and examine their…

定量方法 · 定量生物学 2009-05-21 Yasser Roudi , Joanna Tyrcha , John Hertz

Accurate compensation of brain deformation is a critical challenge for reliable image-guided neurosurgery, as surgical manipulation and tumor resection induce tissue motion that misaligns preoperative planning images with intraoperative…

Learning-based methods have demonstrated remarkable performance in solving inverse problems, particularly in image reconstruction tasks. Despite their success, these approaches often lack theoretical guarantees, which are crucial in…

数值分析 · 数学 2025-10-21 Clemens Arndt , Judith Nickel

We investigate the state space reconstruction from multiple time series derived from continuous and discrete systems and propose a method for building embedding vectors progressively using information measure criteria regarding past,…

混沌动力学 · 物理学 2015-05-19 Ioannis Vlachos , Dimitris Kugiumtzis

Learning to optimize the area under the receiver operating characteristics curve (AUC) performance for imbalanced data has attracted much attention in recent years. Although there have been several methods of AUC optimization, scaling up…

机器学习 · 计算机科学 2024-10-28 Chao Wang , Kai Wu , Jing Liu

The brain is a complex system comprising a myriad of interacting elements, posing significant challenges in understanding its structure, function, and dynamics. Network science has emerged as a powerful tool for studying such intricate…

The bulk of the research effort on brain connectivity revolves around statistical associations among brain regions, which do not directly relate to the causal mechanisms governing brain dynamics. Here we propose the multiscale causal…

机器学习 · 计算机科学 2024-03-21 Gabriele D'Acunto , Francesco Bonchi , Gianmarco De Francisci Morales , Giovanni Petri

For the last decade, convolutional neural networks (CNNs) have vastly superseded their predecessors in nearly all vision tasks in artificial intelligence, including object recognition. However, despite abundant advancements, they continue…

计算机视觉与模式识别 · 计算机科学 2023-02-09 Brandon RichardWebster , Justin Dulay , Anthony DiFalco , Elisabetta Caldesi , Walter J. Scheirer

Autism is one of the most important neurological disorders which leads to problems in a person's social interactions. Improvement of brain imaging technologies and techniques help us to build brain structural and functional networks.…

机器学习 · 计算机科学 2021-03-26 Mohammad Amin , Farshad Safaei

Perceptions and actions, thoughts and memories result from coordinated activity in hundreds or even thousands of neurons in the brain. It is an old dream of the physics community to provide a statistical mechanics description for these and…

无序系统与神经网络 · 物理学 2024-09-04 Leenoy Meshulam , William Bialek

Autoregressive models are ubiquitous tools for the analysis of time series in many domains such as computational neuroscience and biomedical engineering. In these domains, data is, for example, collected from measurements of brain activity.…

信号处理 · 电气工程与系统科学 2023-05-02 Jonas F. Haderlein , Andre D. H. Peterson , Anthony N. Burkitt , Iven M. Y. Mareels , David B. Grayden

Recent advances in experimental neuroscience allow, for the first time, non-invasive studies of the white matter tracts in the human central nervous system, thus making available cutting-edge brain anatomical data describing these global…

定量方法 · 定量生物学 2008-11-06 Jonathan J. Crofts , Desmond J. Higham

Coherence is a widely used measure to assess linear relationships between time series. However, it fails to capture nonlinear dependencies. To overcome this limitation, this paper introduces the notion of residual spectral density as a…

统计理论 · 数学 2024-05-21 Yuichi Goto , Xuze Zhang , Benjamin Kedem , Shuo Chen

Our goal is to model and measure functional and effective (directional) connectivity in multichannel brain physiological signals (e.g., electroencephalograms, local field potentials). The difficulties from analyzing these data mainly come…

应用统计 · 统计学 2017-12-04 Lechuan Hu , Norbert Fortin , Hernando Ombao