相关论文: Evaluating hospital infection control measures for…
Bacterial infections are responsible for high mortality worldwide. Antimicrobial resistance underlying the infection, and multifaceted patient's clinical status can hamper the correct choice of antibiotic treatment. Randomized clinical…
Staphylococcus aureus responsible for nosocomial infections is a significant threat to the public health. The increasing resistance of S.aureus to various antibiotics has drawn it to a prime focus for research on designing an appropriate…
Healthcare-associated infections (HAIs) remain a public health problem. Previous work showed intensive care unit (ICU) population structure impacts methicillin-resistant Staphylococcus aureus (MRSA) rates. Unexplored in that work was the…
Emergent antibiotic-resistant bacterial infections are an increasingly significant source of morbidity and mortality. Antibiotic-resistant organisms have a natural reservoir in hospitals, and recent estimates suggest that almost 2 million…
Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterium that leads to severe infections in hospitalized patients. Previous epidemiological research has focused on MRSA transmission, but few studies have examined the influence of…
The US Centers for Disease Control and Prevention (CDC), in 2019, designated Methicillin-resistant Staphylococcus aureus (MRSA) as a serious antimicrobial resistance threat. The risk of acquiring MRSA and suffering life-threatening…
Whole genome sequencing of pathogens from multiple hosts in an epidemic offers the potential to investigate who infected whom with unparalleled resolution, potentially yielding important insights into disease dynamics and the impact of…
Methicillin-resistant Staphylococcus aureus (MRSA) is a significant contributor to the growing concern of antibiotic resistant bacteria, especially given its stubborn persistence in hospitals and other health care facility settings. In…
Methicillin-resistant Staphylococcus aureus (MRSA) is a type of bacteria resistant to certain antibiotics, making it difficult to prevent MRSA infections. Among decades of efforts to conquer infectious diseases caused by MRSA, many studies…
Nosocomial infections have important consequences for patients and hospital staff: they worsen patient outcomes and their management stresses already overburdened health systems. Accurate judgements of whether an infection is nosocomial…
Methicillin-resistant Staphylococcus aureus (MRSA) is a difficult-to-treat infection that only in the European Union affects about 150,000 patients and causes extra costs of 380 million Euros annually to the health-care systems. Increasing…
Yet in spite of advances in hospital treatment, hospitals continue to be a breeding ground for several airborne diseases and for diseases that are transmitted through close contacts like SARS, methicillin-resistant Staphylococcus aureus…
We propose and analyze an epidemiological model for vector borne diseases that integrates a multi-stage vector population and several host sub-populations which may be characterized by a variety of compartmental model types: subpopulations…
Nosocomial infection raises a serious public health problem, as implied by the existence of pathogens characteristic to healthcare and hospital-mediated outbreaks of influenza and SARS. We simulate stochastic SIR dynamics on social…
Multi-resistant organisms (MROs), the bacteria that are resistant to a number of different antibiotics, have been very popular around the world in recent years. They are very difficult to treat but highly infectious in humans. MRSA…
In this paper we first introduce the general stochastic epidemic model for the spread of infectious diseases. Then we give methods for inferring model parameters such as the basic reproduction number $R_0$ and vaccination coverage $v_c$…
Stochastic infectious disease models capture uncertainty in public health outcomes and have become increasingly popular in epidemiological practice. However, calibrating these models to observed data is challenging with existing methods for…
Assessing the practical identifiability of epidemic models is essential for determining whether parameters can be meaningfully estimated from observed data. Monte Carlo (MC) methods provide an accessible and intuitive framework; however,…
Multidrug-resistant Enterobacteriaceae (MDR-E) have become a major public health threat in many European countries. While traditional infection control strategies primarily target the containment of intra-hospital transmission, there is…
We investigate how key epidemiological parameters shape both seasonal epidemics and the persistence of dengue transmission. Our findings confirm known mechanistic drivers of epidemic variability and introduce a ranking of parameter…