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Nested error regression models are useful tools for analysis of grouped data, especially in the case of small area estimation. This paper suggests a nested error regression model using uncertain random effects in which the random effect in…

统计方法学 · 统计学 2017-02-28 Shonosuke Sugasawa , Tatsuya Kubokawa

Microbiome `omics approaches can reveal intriguing relationships between the human microbiome and certain disease states. Along with the identification of specific bacteria taxa associated with diseases, recent scientific advancements…

应用统计 · 统计学 2019-10-07 Shuang Jiang , Guanghua Xiao , Andrew Y. Koh , Qiwei Li , Xiaowei Zhan

The advances of next-generation sequencing technology have accelerated study of the microbiome and stimulated the high throughput profiling of metagenomes. The large volume of sequenced data has encouraged the rise of various studies for…

统计方法学 · 统计学 2019-04-30 Qiwei Li , Shuang Jiang , Andrew Y. Koh , Guanghua Xiao , Xiaowei Zhan

We focus on the problem of uncertainty informed allocation of medical resources (vaccines) to heterogeneous populations for managing epidemic spread. We tackle two related questions: (1) For a compartmental ordinary differential equation…

最优化与控制 · 数学 2023-07-04 Samarth Gupta , Saurabh Amin

Bayesian response adaptive clinical trials are currently evaluating experimental therapies for several diseases. Adaptive decisions, such as pre-planned variations of the randomization probabilities, attempt to accelerate the development of…

统计方法学 · 统计学 2021-05-25 Marta Bonsaglio , Sandra Fortini , Steffen Ventz , Lorenzo Trippa

It has historically been a challenge to perform Bayesian inference in a design-based survey context. The present paper develops a Bayesian model for sampling inference in the presence of inverse-probability weights. We use a hierarchical…

统计方法学 · 统计学 2020-06-24 Yajuan Si , Natesh S. Pillai , Andrew Gelman

Advances in next-generation sequencing technology have enabled the high-throughput profiling of metagenomes and accelerated the microbiome study. Recently, there has been a rise in quantitative studies that aim to decipher the microbiome…

统计方法学 · 统计学 2023-08-29 Kevin C. Lutz , Michael L. Neugent , Tejasv Bedi , Nicole J. De Nisco , Qiwei Li

Bayesian clustering methods have the widely touted advantage of providing a probabilistic characterization of uncertainty in clustering through the posterior distribution. An amazing variety of priors and likelihoods have been proposed for…

统计方法学 · 统计学 2025-11-21 Garritt L. Page , Andrés F. Barrientos , David B. Dahl , David B. Dunson

The elicitation of an ordinal judgment on multiple alternatives is often required in many psychological and behavioral experiments to investigate preference/choice orientation of a specific population. The Plackett-Luce model is one of the…

统计方法学 · 统计学 2016-10-10 Cristina Mollica , Luca Tardella

The ranking problem is to order a collection of units by some unobserved parameter, based on observations from the associated distribution. This problem arises naturally in a number of contexts, such as business, where we may want to rank…

统计方法学 · 统计学 2016-10-28 Toby Kenney , Hao He , Hong Gu

The dynamics of systems biological processes are usually modeled by a system of ordinary differential equations (ODEs) with many unknown parameters that need to be inferred from noisy and sparse measurements. Here, we introduce…

定量方法 · 定量生物学 2022-02-04 Mitchell Daneker , Zhen Zhang , George Em Karniadakis , Lu Lu

Stochastic kinetic models are often used to describe complex biological processes. Typically these models are analytically intractable and have unknown parameters which need to be estimated from observed data. Ideally we would have…

统计计算 · 统计学 2018-03-13 Richard J. Boys , Holly F. Ainsworth , Colin S. Gillespie

Inferring the parameters of ordinary differential equations (ODEs) from noisy observations is an important problem in many scientific fields. Currently, most parameter estimation methods that bypass numerical integration tend to rely on…

统计方法学 · 统计学 2023-10-25 Mingwei Xu , Samuel W. K. Wong , Peijun Sang

We propose a Bayesian test of normality for univariate or multivariate data against alternative nonparametric models characterized by Dirichlet process mixture distributions. The alternative models are based on the principles of embedding…

统计理论 · 数学 2023-04-12 Surya T. Tokdar , Ryan Martin

Bayesian nonparametric methods are a popular choice for analysing survival data due to their ability to flexibly model the distribution of survival times. These methods typically employ a nonparametric prior on the survival function that is…

统计方法学 · 统计学 2022-02-22 Edwin Fong , Brieuc Lehmann

Bacterial growth models are commonly used for the prediction of microbial safety and the shelf life of perishable foods. Growth is affected by several environmental factors such as temperature, acidity level and salt concentration. In this…

应用统计 · 统计学 2014-11-24 A. Paula Palacios , J. Miguel Marín , Emiliano J. Quinto , Michael P. Wiper

Bi-clustering is a useful approach in analyzing biological data when observations come from heterogeneous groups and have a large number of features. We outline a general Bayesian approach in tackling bi-clustering problems in moderate to…

应用统计 · 统计学 2021-02-11 Han Yan , Jiexing Wu , Yang Li , Jun S. Liu

Computer experiments are becoming increasingly important in scientific investigations. In the presence of uncertainty, analysts employ probabilistic sensitivity methods to identify the key-drivers of change in the quantities of interest.…

统计方法学 · 统计学 2024-07-02 Isadora Antoniano-Villalobos , Emanuele Borgonovo , Xuefei Lu

We address the problem of parameter estimation in models of systems biology from noisy observations. The models we consider are characterized by simultaneous deterministic nonlinear differential equations whose parameters are either taken…

机器学习 · 统计学 2017-05-01 Xin Liu , Mahesan Niranjan

We propose new ways to compare two latent distributions when only ordinal data are available and without imposing parametric assumptions on the underlying continuous distributions. First, we contribute identification results. We show how…

计量经济学 · 经济学 2025-01-10 David M. Kaplan , Wei Zhao