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Elementary flux modes (EFMs) are vectors defined from a metabolic reaction network, giving the connections between substrates and products. EFMs-based metabolic flux analysis (MFA) estimates the flux over each EFM from external flux…

最优化与控制 · 数学 2015-04-21 Hildur Æsa Oddsdóttir , Erika Hagrot , Veronique Chotteau , Anders Forsgren

We compare two methods of proving separable reduction theorems in functional analysis -- the method of rich families and the method of elementary submodels. We show that any result proved using rich families holds also when formulated with…

泛函分析 · 数学 2014-04-14 Marek Cuth , Ondrej F. K. Kalenda

Elementary flux modes (EFMs) are pathways through a metabolic reaction network that connect external substrates to products. Using EFMs, a metabolic network can be transformed into its macroscopic counterpart, in which the internal…

最优化与控制 · 数学 2014-10-13 Hildur Æsa Oddsdóttir , Erika Hagrot , Véronique Chotteau , Anders Forsgren

This paper addresses the semantics of weighted argumentation graphs that are bipolar, i.e. contain both attacks and supports for arguments. It builds on previous work by Amgoud, Ben-Naim et. al. We study the various characteristics of…

人工智能 · 计算机科学 2018-09-28 Till Mossakowski , Fabian Neuhaus

Complex biological systems are very robust to genetic and environmental changes at all levels of organization. Many biological functions of Escherichia coli metabolism can be sustained against single-gene or even multiple-gene mutations by…

分子网络 · 定量生物学 2007-08-30 Pan-Jun Kim , Dong-Yup Lee , Tae Yong Kim , Kwang Ho Lee , Hawoong Jeong , Sang Yup Lee , Sunwon Park

The theory of modular deformations is generalized for the category of complex analytic polyhedra which includes germs of complex space as well as any compact complex analytic space. The objective of the theory is a construction of fine…

代数几何 · 数学 2007-05-23 V. P. Palamodov

The heterogeneity of reaction fluxes present in a metabolic network within a single flux state can be exploited to construct the so-called backbone as a reduced version of metabolism. The backbone maintains all significant fluxes producing…

分子网络 · 定量生物学 2016-02-23 Oriol Güell , Francesc Sagués , M. Ángeles Serrano

A recent body of work has demonstrated that Transformer embeddings can be linearly decomposed into well-defined sums of factors, that can in turn be related to specific network inputs or components. There is however still a dearth of work…

计算与语言 · 计算机科学 2023-10-12 Timothee Mickus , Raúl Vázquez

Metabolism displays striking and robust regularities in the forms of modularity and hierarchy, whose composition may be compactly described. This renders metabolic architecture comprehensible as a system, and suggests the order in which…

分子网络 · 定量生物学 2015-06-05 Rogier Braakman , Eric Smith

We give a necessary and sufficient condition for extremality of a supermodular function based on its min-representation by means of (vertices of) the corresponding core polytope. The condition leads to solving a certain simple linear…

组合数学 · 数学 2016-06-28 M. Studený , T. Kroupa

We extend the classical Feferman-Vaught theorem to logic for metric structures. This implies that the reduced powers of elementarily equivalent structures are elementarily equivalent, and therefore they are isomorphic under the Continuum…

逻辑 · 数学 2016-04-06 Saeed Ghasemi

Modular Decomposition focuses on repeatedly identifying a module M (a collection of vertices that shares exactly the same neighbourhood outside of M) and collapsing it into a single vertex. This notion of exactitude of neighbourhood is very…

离散数学 · 计算机科学 2021-01-25 Michel Habib , Lalla Mouatadid , Eric Sopena , Mengchuan Zou

An important problem is to determine under which circumstances a metric on a conformally compact manifold is conformal to a Poincar\'e--Einstein metric. Such conformal rescalings are in general obstructed by conformal invariants of the…

微分几何 · 数学 2021-07-23 Samuel Blitz , A. Rod Gover , Andrew Waldron

The mechanics of a foam typically depends on the bubble geometry, topology, and the material at hand, be it metallic or polymeric, for example. While the foam energy functional for each bubble is typically minimization of surface area for a…

软凝聚态物质 · 物理学 2023-08-25 Kyungeun Kim , Tao Zhang , J. M. Schwarz

It is well-known that every regular language admits a unique minimal deterministic acceptor. Establishing an analogous result for non-deterministic acceptors is significantly more difficult, but nonetheless of great practical importance. To…

形式语言与自动机理论 · 计算机科学 2023-06-16 Stefan Zetzsche , Alexandra Silva , Matteo Sammartino

By "parallelogram geometry" we mean the elementary, "commutative", geometry corresponding to vector addition, and by "trapezoid geometry" a certain "non-commutative deformation" of the former. This text presents an elementary approach via…

历史与综述 · 数学 2013-05-30 Wolfgang Bertram

In this note, we use elementary submodels to prove that a separable monotonically normal compactum can be mapped on a separable metric space via a continuous function whose fibers have cardinality at most 2.

一般拓扑 · 数学 2007-05-23 Todd Eisworth

Conventional particle theories such as the Standard Model have a number of freely adjustable coupling constants and mass parameters, depending on the symmetry algebra of the local gauge group and the representations chosen for the spinor…

广义相对论与量子宇宙学 · 物理学 2015-05-27 Gerard 't Hooft

The geometric and algebraic theory of monomial ideals and multigraded modules is initiated over real-exponent polynomial rings and, more generally, monoid algebras for real polyhedral cones. The main results include the generalization of…

交换代数 · 数学 2025-11-11 Ezra Miller

It is known that no length or time measurements are possible in sub-Planckian regions of spacetime. The Volovich hypothesis postulates that the micro-geometry of spacetime may therefore be assumed to be non-archimedean. In this letter, the…

数学物理 · 物理学 2009-10-20 V. S. Varadarajan , J. Virtanen
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