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Serotonergic, noradrenergic and dopaminergic brainstem (including midbrain) neurons, often exhibit spontaneous and fairly regular spiking with frequencies of order a few Hz, though dopaminergic and noradrenergic neurons only exhibit such…

神经元与认知 · 定量生物学 2017-04-18 Henry C. Tuckwell , Ying Zhou , Nicholas J. Penington

We consider here a single-compartment model of these neurons which is capable of describing many of the known features of spike generation, particularly the slow rhythmic pacemaking activity often observed in these cells in a variety of…

神经元与认知 · 定量生物学 2012-12-06 Henry C. Tuckwell , Nicholas J. Penington

Brain operates at remarkably low signal power. It has been noted that noise may play a constructive role in neural networks and facilitate the subthreshold signaling. The process of spiking pattern excitation at the characteristic neuronal…

神经元与认知 · 定量生物学 2024-08-12 Mariia Sorokina

The spiking activity of single neurons can be well described by a nonlinear integrate-and-fire model that includes somatic adaptation. When exposed to fluctuating inputs sparsely coupled populations of these model neurons exhibit stochastic…

神经元与认知 · 定量生物学 2017-07-20 Moritz Augustin , Josef Ladenbauer , Fabian Baumann , Klaus Obermayer

We propose a biologically inspired model of spiking neurons based on the dynamics of a damped, driven pendulum. Unlike traditional models such as the Leaky Integrate-and-Fire (LIF) neurons, the pendulum neuron incorporates second-order,…

神经与进化计算 · 计算机科学 2025-07-31 Joy Bose

We investigate different dynamical regimes of neuronal network in the CA3 area of the hippocampus. The proposed neuronal circuit includes two fast- and two slowly-spiking cells which are interconnected by means of dynamical synapses. On the…

神经元与认知 · 定量生物学 2015-11-20 Anastasia I. Lavrova , Michael A. Zaks , Lutz Schimansky-Geier

We study a network model of two conductance-based pacemaker neurons of differing natural frequency, coupled with either mutual excitation or inhibition, and receiving shared random inhibitory synaptic input. The networks may phase-lock…

神经元与认知 · 定量生物学 2009-11-13 Ramana Dodla , Charles J. Wilson

At functional scales, cortical behavior results from the complex interplay of a large number of excitable cells operating in noisy environments. Such systems resist to mathematical analysis, and computational neurosciences have largely…

神经元与认知 · 定量生物学 2014-03-05 Mathieu Galtier , Jonathan Touboul

Serotonergic neurons of the dorsal raphe nuclei, with their extensive innervation of nearly the whole brain have important modulatory effects on many cognitive and physiological processes. They play important roles in clinical depression…

神经元与认知 · 定量生物学 2012-12-06 Henry C. Tuckwell

We present a first-order non-homogeneous Markov model for the interspike-interval density of a continuously stimulated spiking neuron. The model allows the conditional interspike-interval density and the stationary interspike-interval…

神经元与认知 · 定量生物学 2012-08-15 J. Tapson , C. Jin , A. van Schaik , R. Etienne-Cummings

Spiking Neural Networks have earned increased recognition in recent years owing to their biological plausibility and event-driven computation. Spiking neurons are the fundamental building components of Spiking Neural Networks. Those neurons…

神经与进化计算 · 计算机科学 2025-06-04 Amr Nabil , T. Nandha Kumar , Haider Abbas F. Almurib

We study the phenomenological model of ensemble of two FitzHugh-Nagumo neuron-like elements with symmetric excitatory couplings. The main advantage of proposed model is the new approach to model of coupling which is implemented by smooth…

A simple model that replicates the dynamics of spiking and spiking-bursting activity of real biological neurons is proposed. The model is a two-dimensional map which contains one fast and one slow variable. The mechanisms behind generation…

混沌动力学 · 物理学 2009-11-07 Nikolai F. Rulkov

A fundamental problem in neuroscience is to characterize the dynamics of spiking from the neurons in a circuit that is involved in learning about a stimulus or a contingency. A key limitation of current methods to analyze neural spiking…

统计方法学 · 统计学 2017-09-29 Yingzhuo Zhang , Noa Malem-Shinitski , Stephen A Allsop , Kay Tye , Demba Ba

Neurons are the central biological objects in understanding how the brain works. The famous Hodgkin-Huxley model, which describes how action potentials of a neuron are initiated and propagated, consists of four coupled nonlinear…

神经元与认知 · 定量生物学 2010-02-01 William Hanan , Dhagash Mehta , Guillaume Moroz , Sepanda Pouryahya

A spiking neuron ``computes'' by transforming a complex dynamical input into a train of action potentials, or spikes. The computation performed by the neuron can be formulated as dimensional reduction, or feature detection, followed by a…

生物物理 · 物理学 2007-05-23 Blaise Aguera y Arcas , Adrienne L. Fairhall , William Bialek

There has been a strong push recently to examine biological scale simulations of neuromorphic algorithms to achieve stronger inference capabilities. This paper presents a set of piecewise linear spiking neuron models, which can reproduce…

机器学习 · 计算机科学 2012-12-18 Hamid Soleimani , Arash Ahmadi , Mohammad Bavandpour

Spikes are the currency in central nervous systems for information transmission and processing. They are also believed to play an essential role in low-power consumption of the biological systems, whose efficiency attracts increasing…

神经与进化计算 · 计算机科学 2020-05-05 Qiang Yu , Shenglan Li , Huajin Tang , Longbiao Wang , Jianwu Dang , Kay Chen Tan

Recurrent neural networks are powerful tools for understanding and modeling computation and representation by populations of neurons. Continuous-variable or "rate" model networks have been analyzed and applied extensively for these…

神经元与认知 · 定量生物学 2016-01-29 Brian DePasquale , Mark M. Churchland , L. F. Abbott

We propose an equivalent circuit model for photonic spike processing laser neurons with an embedded saturable absorber---a simulation model for photonic excitable lasers (SIMPEL). We show that by mapping the laser neuron rate equations into…

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